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The map label for this gene is oprD [H]

Identifier: 146282721

GI number: 146282721

Start: 2598481

End: 2599773

Strand: Direct

Name: oprD [H]

Synonym: PST_2380

Alternate gene names: 146282721

Gene position: 2598481-2599773 (Clockwise)

Preceding gene: 146282719

Following gene: 146282722

Centisome position: 56.89

GC content: 55.22

Gene sequence:

>1293_bases
ATGCTCAAGACCCCCATCGCCCGGGGCGTGGCCCTCGCCACTCTGGGAGCAACACTGGCTATCCCAACCATGGCTCAAGC
CGCCTTCATCGAAGACACCAAGGCTGGCCTGGAACTGCGTAACTTCTATTTCAACCGCGACTATCGCAACGAGGGCGGAA
ACACCGCATCTACCGCTAGCGGCCAGTCGAAGTCCGAAGCTTGGGCTCAAGGTTTCCTGCTGCGCGTTGAGTCGGGCTAT
ACCGAGGGCACCGTTGGTTTTGGTGTTGACGCGCTCGGTCTTCTGGGGGTGAAGCTCGATGGCGGCGCCGGCCGCACTGG
CAGCGGTCTGATGCCCGACAACTACGACCACAAAACTCCAGACGATTGGTCAGAGATCGGGTTTGCGGGCAAGGCAAAAG
TATCCGAGACCGTTCTGAAAGTAGGTACTTTGCAGTTCAAAAATCCTGCCATCGGCACTAGCGACAGCCGCCTGCTGCCT
CAGACTATGCAGGGCGCGCAAATCGTCTCCAAAGAAATCAAAGGTCTGACACTTGATGCTGGCTATGCGAACCGCATCAA
CCATCGCGATTCCACCAACAACCAAGTGATGTCTTTGAATACCGGTGGTCGCCGTGGTATTAGCGTTGATGGTGGCACGC
CGAATAATCAATCTGACGACTTCCGCTTCCTGGGCGGCAGCTATCAAGTCACTAAAGATCTTACTGCCACCTATTACTAC
AGCAACCTTGAAGATCTTTATAAGCAGCACACGTACAACCTTGTGCATGTACTGCCGATTGCTGACGGCCAGTCGCTGAA
GACTGATCTGCGGTACTCGCGCTCCAAAGACGACGGCAACACCAACGTTGACAACAAAGCGTTCGGCGCCATGGTTACGT
ACTCGCTGAGCGGCCATAGCTTCGGCCTCGGCTATCAGAAGATGAGCGGCGACACCGGCTTTGCTTATGTTGGCGGCGCG
ACCGATCCGTTCCTGGTCAACTACGTCCAGATCAATGATTTCGCCAACGCTGATGAGAAATCCTGGCAGGCTCGCTACGA
TTTCAACTTCGCTTCCATCGGTATTCCGGGCTTGACCTTCATGACCCGCTACATCACTGGTGACAACTTCGAGCGCGCCA
ACGGCACCGAAGGAAAGGAGTGGGAACGCGACATGGACATCGGTTACACCTTCCAGGAAGGTGCGCTGAAGAACCTGAAC
GTCAAATGGCGTAACGCAACTGCTCGTAACAACTACGGCAACGACATCGACGAAAACCGTCTGATCGTCAGCTACACCAT
TCCGCTGATGTAA

Upstream 100 bases:

>100_bases
GGCGACTAAAGTCTAAAGGTTGAAAAACCTCTGTAATGTTTTATTGCATGGCGCCGTAAAGAGCGACTTCAGAGCATCAT
CCAACGAGGAGAAATAAGAA

Downstream 100 bases:

>100_bases
TTAGCGGCTATAGCACGATCGTGCCGTAGGACAAGAAAACCCGCTTCGGCGGGTTTTCTTTTGGTTATTTTCCAGATTTG
CCATAGCGACGCGCCAATCT

Product: porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MLKTPIARGVALATLGATLAIPTMAQAAFIEDTKAGLELRNFYFNRDYRNEGGNTASTASGQSKSEAWAQGFLLRVESGY
TEGTVGFGVDALGLLGVKLDGGAGRTGSGLMPDNYDHKTPDDWSEIGFAGKAKVSETVLKVGTLQFKNPAIGTSDSRLLP
QTMQGAQIVSKEIKGLTLDAGYANRINHRDSTNNQVMSLNTGGRRGISVDGGTPNNQSDDFRFLGGSYQVTKDLTATYYY
SNLEDLYKQHTYNLVHVLPIADGQSLKTDLRYSRSKDDGNTNVDNKAFGAMVTYSLSGHSFGLGYQKMSGDTGFAYVGGA
TDPFLVNYVQINDFANADEKSWQARYDFNFASIGIPGLTFMTRYITGDNFERANGTEGKEWERDMDIGYTFQEGALKNLN
VKWRNATARNNYGNDIDENRLIVSYTIPLM

Sequences:

>Translated_430_residues
MLKTPIARGVALATLGATLAIPTMAQAAFIEDTKAGLELRNFYFNRDYRNEGGNTASTASGQSKSEAWAQGFLLRVESGY
TEGTVGFGVDALGLLGVKLDGGAGRTGSGLMPDNYDHKTPDDWSEIGFAGKAKVSETVLKVGTLQFKNPAIGTSDSRLLP
QTMQGAQIVSKEIKGLTLDAGYANRINHRDSTNNQVMSLNTGGRRGISVDGGTPNNQSDDFRFLGGSYQVTKDLTATYYY
SNLEDLYKQHTYNLVHVLPIADGQSLKTDLRYSRSKDDGNTNVDNKAFGAMVTYSLSGHSFGLGYQKMSGDTGFAYVGGA
TDPFLVNYVQINDFANADEKSWQARYDFNFASIGIPGLTFMTRYITGDNFERANGTEGKEWERDMDIGYTFQEGALKNLN
VKWRNATARNNYGNDIDENRLIVSYTIPLM
>Mature_430_residues
MLKTPIARGVALATLGATLAIPTMAQAAFIEDTKAGLELRNFYFNRDYRNEGGNTASTASGQSKSEAWAQGFLLRVESGY
TEGTVGFGVDALGLLGVKLDGGAGRTGSGLMPDNYDHKTPDDWSEIGFAGKAKVSETVLKVGTLQFKNPAIGTSDSRLLP
QTMQGAQIVSKEIKGLTLDAGYANRINHRDSTNNQVMSLNTGGRRGISVDGGTPNNQSDDFRFLGGSYQVTKDLTATYYY
SNLEDLYKQHTYNLVHVLPIADGQSLKTDLRYSRSKDDGNTNVDNKAFGAMVTYSLSGHSFGLGYQKMSGDTGFAYVGGA
TDPFLVNYVQINDFANADEKSWQARYDFNFASIGIPGLTFMTRYITGDNFERANGTEGKEWERDMDIGYTFQEGALKNLN
VKWRNATARNNYGNDIDENRLIVSYTIPLM

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 46983; Mature: 46983

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTPIARGVALATLGATLAIPTMAQAAFIEDTKAGLELRNFYFNRDYRNEGGNTASTAS
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHEEECCCHHCCCCCCCCCCC
GQSKSEAWAQGFLLRVESGYTEGTVGFGVDALGLLGVKLDGGAGRTGSGLMPDNYDHKTP
CCCHHHHHHCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCC
DDWSEIGFAGKAKVSETVLKVGTLQFKNPAIGTSDSRLLPQTMQGAQIVSKEIKGLTLDA
CCHHHCCCCCCCHHHHHHHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEC
GYANRINHRDSTNNQVMSLNTGGRRGISVDGGTPNNQSDDFRFLGGSYQVTKDLTATYYY
CCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCEEEECCCEEEECCCEEEEEH
SNLEDLYKQHTYNLVHVLPIADGQSLKTDLRYSRSKDDGNTNVDNKAFGAMVTYSLSGHS
HHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCE
FGLGYQKMSGDTGFAYVGGATDPFLVNYVQINDFANADEKSWQARYDFNFASIGIPGLTF
ECCCHHCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEECCCEEEECCCHHHH
MTRYITGDNFERANGTEGKEWERDMDIGYTFQEGALKNLNVKWRNATARNNYGNDIDENR
HHHHHCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCC
LIVSYTIPLM
EEEEEECCCC
>Mature Secondary Structure
MLKTPIARGVALATLGATLAIPTMAQAAFIEDTKAGLELRNFYFNRDYRNEGGNTASTAS
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHEEECCCHHCCCCCCCCCCC
GQSKSEAWAQGFLLRVESGYTEGTVGFGVDALGLLGVKLDGGAGRTGSGLMPDNYDHKTP
CCCHHHHHHCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCC
DDWSEIGFAGKAKVSETVLKVGTLQFKNPAIGTSDSRLLPQTMQGAQIVSKEIKGLTLDA
CCHHHCCCCCCCHHHHHHHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEC
GYANRINHRDSTNNQVMSLNTGGRRGISVDGGTPNNQSDDFRFLGGSYQVTKDLTATYYY
CCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCEEEECCCEEEECCCEEEEEH
SNLEDLYKQHTYNLVHVLPIADGQSLKTDLRYSRSKDDGNTNVDNKAFGAMVTYSLSGHS
HHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCE
FGLGYQKMSGDTGFAYVGGATDPFLVNYVQINDFANADEKSWQARYDFNFASIGIPGLTF
ECCCHHCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEECCCEEEECCCHHHH
MTRYITGDNFERANGTEGKEWERDMDIGYTFQEGALKNLNVKWRNATARNNYGNDIDENR
HHHHHCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCC
LIVSYTIPLM
EEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]