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The map label for this gene is ubiG

Identifier: 146282667

GI number: 146282667

Start: 2537991

End: 2538689

Strand: Direct

Name: ubiG

Synonym: PST_2323

Alternate gene names: 146282667

Gene position: 2537991-2538689 (Clockwise)

Preceding gene: 146282666

Following gene: 146282668

Centisome position: 55.57

GC content: 59.66

Gene sequence:

>699_bases
ATGAGCAACGTCGACCACGCTGAAATCGCCAAATTCGAAGCCCTTGCACATCGCTGGTGGGATCGCGAGAGTGAGTTCAA
GCCACTGCATGAGATCAATCCATTACGGGTCAATTGGATAGACGAGCACATCTCTCTGGCCGGAAAGAAAGTCATCGACA
TCGGCTGCGGTGGCGGCATCCTGAGCGAGGCCATGGCGCAGCGTGGCGCTCAGGTGACTGGCATCGACATGGGCGAGGCT
CCGCTGTCGGTTGCGCGCCTGCACCTTCTCGAATCCGGACTCGAAATCGATTATCGGCAGATCACCGCCGAAGCCATGGC
CGCAGAGGCACCGGAGCAGTTCGACGTGGTCACCTGTCTTGAGATGCTCGAACACGTACCGGACCCGGCCTCCGTCATCC
GGGCCTGCGCCACACTGGTCAAACCGGGCGGCCAGGTGTTCTTCTCCACCATCAACCGCAACCCGAAAGCCTACGCGTTC
GCCATCATCGGCGCGGAGTATGTGTTGCAGCTGCTTCCGCGCGGCACACATGATTTCAAGAAATTCATCCGTCCTTCCGA
GCTCGGCGCCTGGAGCCGTGATGCCGGCTTGGCCGTGAAGGACATCATCGGCCTTACCTATAACCCGCTGACCAAGCACT
ACAAGCTGTCGGCGGACGTCGACGTCAACTACATGGTCCAGACCGTCAAGGAGTCCTGA

Upstream 100 bases:

>100_bases
GCGACCGAATGACCTATGCGCCCTCGCCGCTATCCGAAGCTGGCAACATGAGCGATTGCAGCTCAAGCTTCTTCTTCAAG
CTTTATAAACGGACCAGACC

Downstream 100 bases:

>100_bases
TGCGCCTGCGCGCTGTTCTGTTCGACATGGACGGTACCCTGCTCGATACCGCTCCCGATTTCATCGCCGTGGCGCAGGCC
ATGCGGATTGCGCGCGGCCT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSNVDHAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDEHISLAGKKVIDIGCGGGILSEAMAQRGAQVTGIDMGEA
PLSVARLHLLESGLEIDYRQITAEAMAAEAPEQFDVVTCLEMLEHVPDPASVIRACATLVKPGGQVFFSTINRNPKAYAF
AIIGAEYVLQLLPRGTHDFKKFIRPSELGAWSRDAGLAVKDIIGLTYNPLTKHYKLSADVDVNYMVQTVKES

Sequences:

>Translated_232_residues
MSNVDHAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDEHISLAGKKVIDIGCGGGILSEAMAQRGAQVTGIDMGEA
PLSVARLHLLESGLEIDYRQITAEAMAAEAPEQFDVVTCLEMLEHVPDPASVIRACATLVKPGGQVFFSTINRNPKAYAF
AIIGAEYVLQLLPRGTHDFKKFIRPSELGAWSRDAGLAVKDIIGLTYNPLTKHYKLSADVDVNYMVQTVKES
>Mature_231_residues
SNVDHAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDEHISLAGKKVIDIGCGGGILSEAMAQRGAQVTGIDMGEAP
LSVARLHLLESGLEIDYRQITAEAMAAEAPEQFDVVTCLEMLEHVPDPASVIRACATLVKPGGQVFFSTINRNPKAYAFA
IIGAEYVLQLLPRGTHDFKKFIRPSELGAWSRDAGLAVKDIIGLTYNPLTKHYKLSADVDVNYMVQTVKES

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=245, Percent_Identity=35.1020408163265, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1788564, Length=227, Percent_Identity=62.9955947136564, Blast_Score=308, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI115533050, Length=241, Percent_Identity=32.7800829875519, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324476, Length=257, Percent_Identity=29.9610894941634, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=31.5573770491803, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24585589, Length=265, Percent_Identity=29.811320754717, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_PSEU5 (A4VLX7)

Other databases:

- EMBL:   CP000304
- RefSeq:   YP_001172820.1
- ProteinModelPortal:   A4VLX7
- STRING:   A4VLX7
- GeneID:   5098403
- GenomeReviews:   CP000304_GR
- KEGG:   psa:PST_2323
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   A4VLX7
- ProtClustDB:   PRK05134
- BioCyc:   PSTU379731:PST_2323-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 25655; Mature: 25523

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDHAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDEHISLAGKKVIDIGCGGGI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEHHHHHHHCCCEEEEECCCCHH
LSEAMAQRGAQVTGIDMGEAPLSVARLHLLESGLEIDYRQITAEAMAAEAPEQFDVVTCL
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
EMLEHVPDPASVIRACATLVKPGGQVFFSTINRNPKAYAFAIIGAEYVLQLLPRGTHDFK
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEHHHHHHHHHHCCCCHHHH
KFIRPSELGAWSRDAGLAVKDIIGLTYNPLTKHYKLSADVDVNYMVQTVKES
HHCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
SNVDHAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDEHISLAGKKVIDIGCGGGI
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEHHHHHHHCCCEEEEECCCCHH
LSEAMAQRGAQVTGIDMGEAPLSVARLHLLESGLEIDYRQITAEAMAAEAPEQFDVVTCL
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
EMLEHVPDPASVIRACATLVKPGGQVFFSTINRNPKAYAFAIIGAEYVLQLLPRGTHDFK
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEHHHHHHHHHHCCCCHHHH
KFIRPSELGAWSRDAGLAVKDIIGLTYNPLTKHYKLSADVDVNYMVQTVKES
HHCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA