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The map label for this gene is trxB1 [H]

Identifier: 146282642

GI number: 146282642

Start: 2504966

End: 2505913

Strand: Direct

Name: trxB1 [H]

Synonym: PST_2294

Alternate gene names: 146282642

Gene position: 2504966-2505913 (Clockwise)

Preceding gene: 146282635

Following gene: 146282643

Centisome position: 54.84

GC content: 63.71

Gene sequence:

>948_bases
ATGAGTGAAGTCAAGCATTCGCGTCTGATCATCCTCGGCTCGGGCCCGGCCGGTTATACCGCTGCGGTATACGCTGCCCG
CGCCAACCTGAAGCCACTGATGATCACCGGCATCCAGCCCGGCGGCCAGCTGACCACCACCACCGAGGTCGACAACTGGC
CTGGCGACGTCGAAGGCCTGACCGGCCCGGATCTGATGGTGCGCATGCAGAACCACGCCGAGCGCTTCGACACCGAGATC
GTCTTCGATCACATCCATACCGCCGAGTTGCAGCAGCGCCCGTTCACCTTGCGCGGTGACAGCGGCGTCTACACCTGCGA
TGCGCTGATCATCGCAACAGGCGCTTCGGCGCAGTATCTCGGCCTGCCCTCCGAAGAAGCATTCGCCGGTCGCGGCGTAT
CCGCCTGCGCCACCTGTGACGGCTTCTTCTACCGCAACCAGGTGGTCGCGGTGATCGGTGGCGGCAATACCGCGGTCGAG
GAGGCGCTGTACCTGTCCAACATCGCCAAGGAAGTCCACCTGATCCACCGCCGCGACAAGCTCCGCTCGGAGAAGATCCT
GCAGGACAAGATCATGGACAAGGCGACCAACGGCAACATACGCCTGCACTGGAACCACACCCTCGAGGAAGTGCTCGGCG
ACGCCAGCGGCGTGACCGGCGTTCGCCTCAAGAGCACCCTCACTGGTGAAGAAAACACGCTGGACCTCGCGGGCGTATTC
ATCGCCATCGGCCACAAGCCGAACACCGACCTGTTCCAGGGCCAGCTGGAGATGAAGGATGGCTACCTGAAGATCCGCGG
CGGCGGTGAAGGCGATGCCACCTGCACCAGCATTCCCGGAGTGTTCGCCGCAGGCGATGTGGCCGACCACGTCTATCGCC
AGGCCATCACCTCGGCAGGCGCCGGCTGCATGGCGGCACTGGATGCCGAGAAGTACCTGGACAATTGA

Upstream 100 bases:

>100_bases
TTTTGCCGATGCTTCGGTGTAGCATAAACGCCCGATTTCCCGGCGCGGCTCGACTGGAGCACGCTTCTCTATTTGCAACA
AAGGCTTATGAGGGCTTTTT

Downstream 100 bases:

>100_bases
TCCCAGGCGGGCTTCGGCCCGCCCTCCCCTACCCTGCGTGCCGACATGCTGACCTGGCTAAAGCGCGACGACCTCAGCTT
TCCTCCCCTCGAAACGGCTC

Product: thioredoxin reductase 1

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSEVKHSRLIILGSGPAGYTAAVYAARANLKPLMITGIQPGGQLTTTTEVDNWPGDVEGLTGPDLMVRMQNHAERFDTEI
VFDHIHTAELQQRPFTLRGDSGVYTCDALIIATGASAQYLGLPSEEAFAGRGVSACATCDGFFYRNQVVAVIGGGNTAVE
EALYLSNIAKEVHLIHRRDKLRSEKILQDKIMDKATNGNIRLHWNHTLEEVLGDASGVTGVRLKSTLTGEENTLDLAGVF
IAIGHKPNTDLFQGQLEMKDGYLKIRGGGEGDATCTSIPGVFAAGDVADHVYRQAITSAGAGCMAALDAEKYLDN

Sequences:

>Translated_315_residues
MSEVKHSRLIILGSGPAGYTAAVYAARANLKPLMITGIQPGGQLTTTTEVDNWPGDVEGLTGPDLMVRMQNHAERFDTEI
VFDHIHTAELQQRPFTLRGDSGVYTCDALIIATGASAQYLGLPSEEAFAGRGVSACATCDGFFYRNQVVAVIGGGNTAVE
EALYLSNIAKEVHLIHRRDKLRSEKILQDKIMDKATNGNIRLHWNHTLEEVLGDASGVTGVRLKSTLTGEENTLDLAGVF
IAIGHKPNTDLFQGQLEMKDGYLKIRGGGEGDATCTSIPGVFAAGDVADHVYRQAITSAGAGCMAALDAEKYLDN
>Mature_314_residues
SEVKHSRLIILGSGPAGYTAAVYAARANLKPLMITGIQPGGQLTTTTEVDNWPGDVEGLTGPDLMVRMQNHAERFDTEIV
FDHIHTAELQQRPFTLRGDSGVYTCDALIIATGASAQYLGLPSEEAFAGRGVSACATCDGFFYRNQVVAVIGGGNTAVEE
ALYLSNIAKEVHLIHRRDKLRSEKILQDKIMDKATNGNIRLHWNHTLEEVLGDASGVTGVRLKSTLTGEENTLDLAGVFI
AIGHKPNTDLFQGQLEMKDGYLKIRGGGEGDATCTSIPGVFAAGDVADHVYRQAITSAGAGCMAALDAEKYLDN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=73.6507936507937, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI87081763, Length=301, Percent_Identity=31.5614617940199, Blast_Score=144, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=46.25, Blast_Score=279, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=45.2307692307692, Blast_Score=277, Evalue=2e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33721; Mature: 33590

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVKHSRLIILGSGPAGYTAAVYAARANLKPLMITGIQPGGQLTTTTEVDNWPGDVEGL
CCCCCCCEEEEEECCCCCCHHEEEEHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
TGPDLMVRMQNHAERFDTEIVFDHIHTAELQQRPFTLRGDSGVYTCDALIIATGASAQYL
CCCHHEEEEHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEECCCCEEE
GLPSEEAFAGRGVSACATCDGFFYRNQVVAVIGGGNTAVEEALYLSNIAKEVHLIHRRDK
CCCCCHHHCCCCCCHHHHHCCEEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LRSEKILQDKIMDKATNGNIRLHWNHTLEEVLGDASGVTGVRLKSTLTGEENTLDLAGVF
HHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEE
IAIGHKPNTDLFQGQLEMKDGYLKIRGGGEGDATCTSIPGVFAAGDVADHVYRQAITSAG
EEECCCCCCHHEECEEEECCCEEEEEECCCCCCEEECCCCCEECCHHHHHHHHHHHHHCC
AGCMAALDAEKYLDN
CCCEEECCHHHHHCC
>Mature Secondary Structure 
SEVKHSRLIILGSGPAGYTAAVYAARANLKPLMITGIQPGGQLTTTTEVDNWPGDVEGL
CCCCCCEEEEEECCCCCCHHEEEEHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
TGPDLMVRMQNHAERFDTEIVFDHIHTAELQQRPFTLRGDSGVYTCDALIIATGASAQYL
CCCHHEEEEHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEECCCCEEE
GLPSEEAFAGRGVSACATCDGFFYRNQVVAVIGGGNTAVEEALYLSNIAKEVHLIHRRDK
CCCCCHHHCCCCCCHHHHHCCEEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LRSEKILQDKIMDKATNGNIRLHWNHTLEEVLGDASGVTGVRLKSTLTGEENTLDLAGVF
HHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEE
IAIGHKPNTDLFQGQLEMKDGYLKIRGGGEGDATCTSIPGVFAAGDVADHVYRQAITSAG
EEECCCCCCHHEECEEEECCCEEEEEECCCCCCEEECCCCCEECCHHHHHHHHHHHHHCC
AGCMAALDAEKYLDN
CCCEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]