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The map label for this gene is aglA [H]

Identifier: 145301107

GI number: 145301107

Start: 4574278

End: 4575867

Strand: Direct

Name: aglA [H]

Synonym: ASA_4276

Alternate gene names: 145301107

Gene position: 4574278-4575867 (Clockwise)

Preceding gene: 145301106

Following gene: 145301108

Centisome position: 97.28

GC content: 53.84

Gene sequence:

>1590_bases
ATGCTCAGTCAAATTCAACGCTTTGGCGGAGCAATGTTTACTCCTGTACTACTGTTTCCATTTGCAGGTATGGTAGTGGG
CATTGCAATCATGCTGAAAAATCCCATGTTTGTGGGAGAGGCGCTGGCAAACCCGCAAGGTTTGTTTTTTCAAATAGTAC
ATATTATTGAAGAAGGTGGCTGGACCGTATTCAGAAACATGCCGCTTATATTTGCCATCGGCTTGCCGATTGGGCTGGCA
AATAAGGCGCAGGCACGAGCCTGTCTCTCCGTATTGGTCAGCTTCATGACCTGGAATTATTTCATCAATGCCATGGGGAT
GACCTGGGGCGACTATTTCGGGGTCGATTTCAATCAGGCGGTCGGCGGCGAAAGCGGCCTGGCCATGGTAGCGGGGATCA
AGACGCTGGATACCAGCATCATAGGGGCCATCGTTATCTCGGGTATCGTCACCGCCCTGCACAACCGCCTGTTTGATCGA
CAGCTTCCCGTCTTTCTCGGCATCTTTCAGGGCAGCTCGTTTGTCACCATCATCGCCTTCTTCGTCATGATCCCCTGTGC
CTGGCTGACCCTGCTGGGGTGGCCCAAGGTACAGATGGGTATCGCCTCCCTGCAGGAGTTCATGCTGATTTCGGGCCCGC
TCGGTGTCTGGGTCTACACCTTCCTCGAGCGCATTCTTATCCCGACCGGCCTGCATCACTTTATCTATGGCCCCTTCATC
TTCGGCCCTGCCGCGGTGGAAGGCGGCATCCAGCTCTACTGGGCCCAGCATCTGCAGGAGTTCAGCCAGAGCACGCGTCC
GCTCATCGAGCTGTTCCCCCAGGGTGGCTTCGCCCTGCACGGCAACTCGAAGATTTTCGGTGCCATGGGGATTGCCCTGG
CCATCTACGCCACTGCCGCCCGTGAGAACAAGGCCAAGGTGGCAGGCCTGCTGATCCCAGCGACCCTGACCGCCATGCTG
GTGGGCATCACGGAGCCGCTGGAGTTCACCTTCCTCTTCATCTCGCCTCTGCTGTTTGCCATCCATGCCCTGCTGGCTGC
CACCATGGCCACCGTCATGTACCTGTTCGGCGTCGTCGGCAACATGGGCGGCGGCCTGCTCGACCAGTTCCTGCCGCAAA
ACTGGATCCCCATGTTCCACAACCATGCCAGCATGATGTTTACCCAGATAGCCATAGGCCTGGCGTTCACCGGACTCTGG
TTCCTGATATTCAGAAGCCTCATTCTGAGATTAAATTTAAAAACCCCGGGACGGGAAGACAGCGAAATAAAGCTTTATTC
AAAAGCAGATTATCAGACAGCCAAACAACAGCGGGGTGGTGATATTGCAACTCAAATTATTGAAGCACTCGGCGGCAGCA
AAAATATAAGAAGCCTGAATAATTGTGCCACCCGATTAAGAATATCGCTGATAAATGCCAGCCAGGCTGCGGCAGATGAA
GTTTTCAAACAACTGGGCGCCCATGGAGTGGTTCGTCATGGCGACAGCATTCAAATAATCATAGGTCTGCATGTGCCACA
GGTACGTGAAAATATGGAATCGATAATGAACAACCCCACTCAATCCTCTTCTCTCGTAACGGAGTCATGA

Upstream 100 bases:

>100_bases
CACTTCGAAGTTGAATTCGCGCTTTACCCATTGTTGTTAGGTTCAATTCAGCAACACAGACAACACCCTATCAAAAACTC
TTTTAATAAAGGGACAATAT

Downstream 100 bases:

>100_bases
TCATGAAAAAATTCTCTGTAGTCATCGCCGGCGGCGGCAGCACTTTCACACCGGGTATCGTCCTCATGCTGCTCGAGAAC
CAGCATCGTTTCCCGCTCAA

Product: PTS system alpha-glucoside-specific EIICB component

Products: NA

Alternate protein names: Alpha-glucoside permease IIC component; PTS system alpha-glucoside-specific EIIC component; Alpha-glucoside-specific phosphotransferase enzyme IIB component; PTS system alpha-glucoside-specific EIIB component [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MLSQIQRFGGAMFTPVLLFPFAGMVVGIAIMLKNPMFVGEALANPQGLFFQIVHIIEEGGWTVFRNMPLIFAIGLPIGLA
NKAQARACLSVLVSFMTWNYFINAMGMTWGDYFGVDFNQAVGGESGLAMVAGIKTLDTSIIGAIVISGIVTALHNRLFDR
QLPVFLGIFQGSSFVTIIAFFVMIPCAWLTLLGWPKVQMGIASLQEFMLISGPLGVWVYTFLERILIPTGLHHFIYGPFI
FGPAAVEGGIQLYWAQHLQEFSQSTRPLIELFPQGGFALHGNSKIFGAMGIALAIYATAARENKAKVAGLLIPATLTAML
VGITEPLEFTFLFISPLLFAIHALLAATMATVMYLFGVVGNMGGGLLDQFLPQNWIPMFHNHASMMFTQIAIGLAFTGLW
FLIFRSLILRLNLKTPGREDSEIKLYSKADYQTAKQQRGGDIATQIIEALGGSKNIRSLNNCATRLRISLINASQAAADE
VFKQLGAHGVVRHGDSIQIIIGLHVPQVRENMESIMNNPTQSSSLVTES

Sequences:

>Translated_529_residues
MLSQIQRFGGAMFTPVLLFPFAGMVVGIAIMLKNPMFVGEALANPQGLFFQIVHIIEEGGWTVFRNMPLIFAIGLPIGLA
NKAQARACLSVLVSFMTWNYFINAMGMTWGDYFGVDFNQAVGGESGLAMVAGIKTLDTSIIGAIVISGIVTALHNRLFDR
QLPVFLGIFQGSSFVTIIAFFVMIPCAWLTLLGWPKVQMGIASLQEFMLISGPLGVWVYTFLERILIPTGLHHFIYGPFI
FGPAAVEGGIQLYWAQHLQEFSQSTRPLIELFPQGGFALHGNSKIFGAMGIALAIYATAARENKAKVAGLLIPATLTAML
VGITEPLEFTFLFISPLLFAIHALLAATMATVMYLFGVVGNMGGGLLDQFLPQNWIPMFHNHASMMFTQIAIGLAFTGLW
FLIFRSLILRLNLKTPGREDSEIKLYSKADYQTAKQQRGGDIATQIIEALGGSKNIRSLNNCATRLRISLINASQAAADE
VFKQLGAHGVVRHGDSIQIIIGLHVPQVRENMESIMNNPTQSSSLVTES
>Mature_529_residues
MLSQIQRFGGAMFTPVLLFPFAGMVVGIAIMLKNPMFVGEALANPQGLFFQIVHIIEEGGWTVFRNMPLIFAIGLPIGLA
NKAQARACLSVLVSFMTWNYFINAMGMTWGDYFGVDFNQAVGGESGLAMVAGIKTLDTSIIGAIVISGIVTALHNRLFDR
QLPVFLGIFQGSSFVTIIAFFVMIPCAWLTLLGWPKVQMGIASLQEFMLISGPLGVWVYTFLERILIPTGLHHFIYGPFI
FGPAAVEGGIQLYWAQHLQEFSQSTRPLIELFPQGGFALHGNSKIFGAMGIALAIYATAARENKAKVAGLLIPATLTAML
VGITEPLEFTFLFISPLLFAIHALLAATMATVMYLFGVVGNMGGGLLDQFLPQNWIPMFHNHASMMFTQIAIGLAFTGLW
FLIFRSLILRLNLKTPGREDSEIKLYSKADYQTAKQQRGGDIATQIIEALGGSKNIRSLNNCATRLRISLINASQAAADE
VFKQLGAHGVVRHGDSIQIIIGLHVPQVRENMESIMNNPTQSSSLVTES

Specific function: Involved in the transport and simultaneous phosphorylation at O-6 of the glucosyl moiety of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses. Can also transport maltose, isomaltose and maltitol, phosphorylating at O-6 of their non-reduci

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=523, Percent_Identity=30.4015296367113, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1787908, Length=530, Percent_Identity=32.4528301886792, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1786894, Length=523, Percent_Identity=29.8279158699809, Blast_Score=168, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57715; Mature: 57715

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSQIQRFGGAMFTPVLLFPFAGMVVGIAIMLKNPMFVGEALANPQGLFFQIVHIIEEGG
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCC
WTVFRNMPLIFAIGLPIGLANKAQARACLSVLVSFMTWNYFINAMGMTWGDYFGVDFNQA
EEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VGGESGLAMVAGIKTLDTSIIGAIVISGIVTALHNRLFDRQLPVFLGIFQGSSFVTIIAF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHH
FVMIPCAWLTLLGWPKVQMGIASLQEFMLISGPLGVWVYTFLERILIPTGLHHFIYGPFI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCHH
FGPAAVEGGIQLYWAQHLQEFSQSTRPLIELFPQGGFALHGNSKIFGAMGIALAIYATAA
CCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
RENKAKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAIHALLAATMATVMYLFGVVG
HCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMGGGLLDQFLPQNWIPMFHNHASMMFTQIAIGLAFTGLWFLIFRSLILRLNLKTPGRED
CCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
SEIKLYSKADYQTAKQQRGGDIATQIIEALGGSKNIRSLNNCATRLRISLINASQAAADE
CCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCHHHHHHH
VFKQLGAHGVVRHGDSIQIIIGLHVPQVRENMESIMNNPTQSSSLVTES
HHHHHCCCCEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLSQIQRFGGAMFTPVLLFPFAGMVVGIAIMLKNPMFVGEALANPQGLFFQIVHIIEEGG
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCC
WTVFRNMPLIFAIGLPIGLANKAQARACLSVLVSFMTWNYFINAMGMTWGDYFGVDFNQA
EEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VGGESGLAMVAGIKTLDTSIIGAIVISGIVTALHNRLFDRQLPVFLGIFQGSSFVTIIAF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHH
FVMIPCAWLTLLGWPKVQMGIASLQEFMLISGPLGVWVYTFLERILIPTGLHHFIYGPFI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCHH
FGPAAVEGGIQLYWAQHLQEFSQSTRPLIELFPQGGFALHGNSKIFGAMGIALAIYATAA
CCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
RENKAKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAIHALLAATMATVMYLFGVVG
HCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMGGGLLDQFLPQNWIPMFHNHASMMFTQIAIGLAFTGLWFLIFRSLILRLNLKTPGRED
CCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
SEIKLYSKADYQTAKQQRGGDIATQIIEALGGSKNIRSLNNCATRLRISLINASQAAADE
CCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCHHHHHHH
VFKQLGAHGVVRHGDSIQIIIGLHVPQVRENMESIMNNPTQSSSLVTES
HHHHHCCCCEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11473129; 11322729 [H]