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The map label for this gene is coaD [H]

Identifier: 145301058

GI number: 145301058

Start: 4516824

End: 4517306

Strand: Direct

Name: coaD [H]

Synonym: ASA_4223

Alternate gene names: 145301058

Gene position: 4516824-4517306 (Clockwise)

Preceding gene: 145301056

Following gene: 145301065

Centisome position: 96.05

GC content: 59.42

Gene sequence:

>483_bases
ATGACCAACAAGGTAATTTATCCCGGCACCTTCGACCCCATCACCAACGGCCATACCGATCTGATAGGTCGTGCCGCCAG
GCTGTTTGATGAAGTGGTCGTCGGGGTAGCCAACAGCCCGAGCAAGCGCCCCTTGTTCGATCTGGCAGAACGTGTCCTGC
TTGCCCGGCAAGTGACGGCCCACCTGCCCAACGTCAAGGTGGTGGGCTTCTCCGGCCTCTTGGTGGACTTTGCCAAAGAG
CAGCAAGCCAACGTGCTGATCCGTGGCTTGCGGGCCGTCTCCGACTTCGAATACGAATTTCAGCTGGCCAACATGAACCG
CCGCCTGATGCCGGAGCTGGAGAGCGTGTTTCTCACCCCTGCCGAAGAGAACTCCTTCATCTCCTCGACCCTGGTGAAGG
AGGTCGCCCTGCATGGCGGTGATATCCGCCAGTTTGTCGACCCGATCGTCGCCAAGGCGATTGCCGCCAAGCAAGGCAAG
TAA

Upstream 100 bases:

>100_bases
CGCGCCAGGTCCCGCACAAAACGGACATCGTCCCGGTCGCGACAAAACATCAACAGACCCTATAATGCGACCAAATTTCC
AGGTTGCAGGAATCAACAGC

Downstream 100 bases:

>100_bases
CAAGCAAACAGGCTACCCGAGGGTAGCCTGTTTAGTGCGGCGCACATGGGCCGCGCTCGCCATTGTCCGCACTGGCAGTC
AGCCCGCCGCGCGACCCAGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTNKVIYPGTFDPITNGHTDLIGRAARLFDEVVVGVANSPSKRPLFDLAERVLLARQVTAHLPNVKVVGFSGLLVDFAKE
QQANVLIRGLRAVSDFEYEFQLANMNRRLMPELESVFLTPAEENSFISSTLVKEVALHGGDIRQFVDPIVAKAIAAKQGK

Sequences:

>Translated_160_residues
MTNKVIYPGTFDPITNGHTDLIGRAARLFDEVVVGVANSPSKRPLFDLAERVLLARQVTAHLPNVKVVGFSGLLVDFAKE
QQANVLIRGLRAVSDFEYEFQLANMNRRLMPELESVFLTPAEENSFISSTLVKEVALHGGDIRQFVDPIVAKAIAAKQGK
>Mature_159_residues
TNKVIYPGTFDPITNGHTDLIGRAARLFDEVVVGVANSPSKRPLFDLAERVLLARQVTAHLPNVKVVGFSGLLVDFAKEQ
QANVLIRGLRAVSDFEYEFQLANMNRRLMPELESVFLTPAEENSFISSTLVKEVALHGGDIRQFVDPIVAKAIAAKQGK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=64.3312101910828, Blast_Score=216, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17605; Mature: 17473

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKVIYPGTFDPITNGHTDLIGRAARLFDEVVVGVANSPSKRPLFDLAERVLLARQVTA
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
HLPNVKVVGFSGLLVDFAKEQQANVLIRGLRAVSDFEYEFQLANMNRRLMPELESVFLTP
HCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCC
AEENSFISSTLVKEVALHGGDIRQFVDPIVAKAIAAKQGK
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNKVIYPGTFDPITNGHTDLIGRAARLFDEVVVGVANSPSKRPLFDLAERVLLARQVTA
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
HLPNVKVVGFSGLLVDFAKEQQANVLIRGLRAVSDFEYEFQLANMNRRLMPELESVFLTP
HCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCC
AEENSFISSTLVKEVALHGGDIRQFVDPIVAKAIAAKQGK
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA