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The map label for this gene is rhtC [H]

Identifier: 145301005

GI number: 145301005

Start: 4450194

End: 4450841

Strand: Direct

Name: rhtC [H]

Synonym: ASA_4159

Alternate gene names: 145301005

Gene position: 4450194-4450841 (Clockwise)

Preceding gene: 145301004

Following gene: 145301007

Centisome position: 94.64

GC content: 65.9

Gene sequence:

>648_bases
ATGTTCACCAGCCTGTTTCTGACCATAGGTCTTATCCACCTGATCGCACTGGCGAGCCCTGGGCCGGACTTCGCGCTGAT
CTTGCGTACCAGCCTGCACAGGCCAACGGCACTGGGGGCGGCGCTCGGCATAGCACTCGCCATCTTGCTGCACGCCACCC
TCAGCCTGACCGGCATCAGCCTGCTGATAGCCGAACATCCCTGGCTCTTCATGGCGGTGAAGGTGGTCGGCGCCCTCTAT
CTGGGTTGGCTCGGTTGGGGGGCGCTCAAGGCCGCCTGGCACAGCTCGGCAACACTGGCCCTCAAGGCTGGCGGAGAGCA
GCAGGGCTGGCGCAAGGGGATAGGGAGCGGGCTTGCCACCAATCTGCTCAATCCCAAGGCGCTGCTGTTCTTCATGGGAC
TGCTGGCGGCCATGGTGACGCCGCAGGTGGACGGGCTGACGCGCGGCCTGCTGGTGCTGGAGCTGTTCCTGCTCTCTCTG
GTCTGGTTCGGCGTGCTGGCCTGGAGCCTCTCCACCCCGCGGGCCCAACGCCTGCTTGGCCGGATCCAGCGTCCACTCAA
TCTGGTCACGGGTCTGCTGTTCGGCGCCGTCAGCCTCTCCATCCTGACCGGCATGGCTGGCGAGGCCTATGCCCTGGTCC
CGCACTGA

Upstream 100 bases:

>100_bases
CCAGCCCGGTCGATGACCGGCAGCAGATGCAATCTTTTACAATCGCCTCCCCGCCCTGATCCCCCATGCTGTCACCTCAT
ACCGTCATCGAGGTTTCACC

Downstream 100 bases:

>100_bases
TCTCCTCCCCCCCCCCATGAAAAAGAGGGATGGCCTGAGCCATCCCTCTTTGCGTTCACACGAATAAAGATCCGCATGAC
AATCTGGTTCACACCGGGCA

Product: amino acid transporter LysE

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MFTSLFLTIGLIHLIALASPGPDFALILRTSLHRPTALGAALGIALAILLHATLSLTGISLLIAEHPWLFMAVKVVGALY
LGWLGWGALKAAWHSSATLALKAGGEQQGWRKGIGSGLATNLLNPKALLFFMGLLAAMVTPQVDGLTRGLLVLELFLLSL
VWFGVLAWSLSTPRAQRLLGRIQRPLNLVTGLLFGAVSLSILTGMAGEAYALVPH

Sequences:

>Translated_215_residues
MFTSLFLTIGLIHLIALASPGPDFALILRTSLHRPTALGAALGIALAILLHATLSLTGISLLIAEHPWLFMAVKVVGALY
LGWLGWGALKAAWHSSATLALKAGGEQQGWRKGIGSGLATNLLNPKALLFFMGLLAAMVTPQVDGLTRGLLVLELFLLSL
VWFGVLAWSLSTPRAQRLLGRIQRPLNLVTGLLFGAVSLSILTGMAGEAYALVPH
>Mature_215_residues
MFTSLFLTIGLIHLIALASPGPDFALILRTSLHRPTALGAALGIALAILLHATLSLTGISLLIAEHPWLFMAVKVVGALY
LGWLGWGALKAAWHSSATLALKAGGEQQGWRKGIGSGLATNLLNPKALLFFMGLLAAMVTPQVDGLTRGLLVLELFLLSL
VWFGVLAWSLSTPRAQRLLGRIQRPLNLVTGLLFGAVSLSILTGMAGEAYALVPH

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=31.5, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786522, Length=201, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22745; Mature: 22745

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTSLFLTIGLIHLIALASPGPDFALILRTSLHRPTALGAALGIALAILLHATLSLTGIS
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLIAEHPWLFMAVKVVGALYLGWLGWGALKAAWHSSATLALKAGGEQQGWRKGIGSGLAT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCHHHH
NLLNPKALLFFMGLLAAMVTPQVDGLTRGLLVLELFLLSLVWFGVLAWSLSTPRAQRLLG
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIQRPLNLVTGLLFGAVSLSILTGMAGEAYALVPH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure
MFTSLFLTIGLIHLIALASPGPDFALILRTSLHRPTALGAALGIALAILLHATLSLTGIS
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLIAEHPWLFMAVKVVGALYLGWLGWGALKAAWHSSATLALKAGGEQQGWRKGIGSGLAT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCHHHH
NLLNPKALLFFMGLLAAMVTPQVDGLTRGLLVLELFLLSLVWFGVLAWSLSTPRAQRLLG
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIQRPLNLVTGLLFGAVSLSILTGMAGEAYALVPH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]