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The map label for this gene is sat [H]

Identifier: 145300756

GI number: 145300756

Start: 4181007

End: 4181672

Strand: Direct

Name: sat [H]

Synonym: ASA_3895

Alternate gene names: 145300756

Gene position: 4181007-4181672 (Clockwise)

Preceding gene: 145300754

Following gene: 145300757

Centisome position: 88.91

GC content: 61.41

Gene sequence:

>666_bases
GTGTGCCGACAGATTCGAAAGGAGAGCACCTTGCACGGACCCGATCCCGCCAATCCCCACCCCATGAAGGGCTTCCCCCA
GGTGTGCTTTATCAAGAACACCATCAAGGGGCCCAATATCGAGGTGGGTGATTACAGCTATTACGACGACCCGGAAGACT
CGGCAGGCTTTGAGCGCAACGTCCTCTATCACTTCCCCTTCATCGGCGACCGGCTCATCATCGGCAAGTTCTGCGCCATC
GCCCGCGGGGTCAAGTTCATCATGAACGGCGCCAACCACCAGAGCTCCGGCTTCTCCACCTACCCCTTCTTTATCTTCGG
CAATGGCTGGGAGAGCGCAGCCCCCGCACCTGGCACGCTGCCTTACAAGGGGGATACGGTGATTGGCAACGATGTCTGGA
TTGGCTATGACACCCTGATTATGCCGGGCGTCAAGGTCGGCAACGGCGCCATTATCGCCGCCCGCTCCGTCGTCACCGGC
GACGTACCCGACTACGCCATCGTCGGCGGCAACCCAGCCCGGGTGATCCGCTACCGCTTTGACGACGACACCATAGCCCG
CCTCAACGCCCTCGCCTGGTGGAACTGGCCGGTGGAGCAGATCAGCCGGAATCTGCTGTTGATCGGTGGCGGGGAGATAG
CCGCACTGGAAGCTGCGGCCCGATAA

Upstream 100 bases:

>100_bases
CCCGCCCCGGGTCGATGCGCACATGACGACGGGGCGACAAAGGCTGGCGAGTGCACCACCACAAAAAGGTGGCAGACCGT
CATCAACTTCCTTTACGGTA

Downstream 100 bases:

>100_bases
ACACCATCAAGCAGGAAGCCCGATGCAAATCACCACACCCCAAACGCCGCAAGAGGATGAGGTCGAGGCACCGCGGATCG
GCCTGTCAGGCTACAACGTG

Product: streptogramin A acetyltransferase

Products: CoA; acetylmaltose [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MCRQIRKESTLHGPDPANPHPMKGFPQVCFIKNTIKGPNIEVGDYSYYDDPEDSAGFERNVLYHFPFIGDRLIIGKFCAI
ARGVKFIMNGANHQSSGFSTYPFFIFGNGWESAAPAPGTLPYKGDTVIGNDVWIGYDTLIMPGVKVGNGAIIAARSVVTG
DVPDYAIVGGNPARVIRYRFDDDTIARLNALAWWNWPVEQISRNLLLIGGGEIAALEAAAR

Sequences:

>Translated_221_residues
MCRQIRKESTLHGPDPANPHPMKGFPQVCFIKNTIKGPNIEVGDYSYYDDPEDSAGFERNVLYHFPFIGDRLIIGKFCAI
ARGVKFIMNGANHQSSGFSTYPFFIFGNGWESAAPAPGTLPYKGDTVIGNDVWIGYDTLIMPGVKVGNGAIIAARSVVTG
DVPDYAIVGGNPARVIRYRFDDDTIARLNALAWWNWPVEQISRNLLLIGGGEIAALEAAAR
>Mature_221_residues
MCRQIRKESTLHGPDPANPHPMKGFPQVCFIKNTIKGPNIEVGDYSYYDDPEDSAGFERNVLYHFPFIGDRLIIGKFCAI
ARGVKFIMNGANHQSSGFSTYPFFIFGNGWESAAPAPGTLPYKGDTVIGNDVWIGYDTLIMPGVKVGNGAIIAARSVVTG
DVPDYAIVGGNPARVIRYRFDDDTIARLNALAWWNWPVEQISRNLLLIGGGEIAALEAAAR

Specific function: Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=50, Percent_Identity=56, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: 2.3.1.79 [C]

Molecular weight: Translated: 24181; Mature: 24181

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRQIRKESTLHGPDPANPHPMKGFPQVCFIKNTIKGPNIEVGDYSYYDDPEDSAGFERN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCC
VLYHFPFIGDRLIIGKFCAIARGVKFIMNGANHQSSGFSTYPFFIFGNGWESAAPAPGTL
EEEECCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCEECCEEEEECCCCCCCCCCCCC
PYKGDTVIGNDVWIGYDTLIMPGVKVGNGAIIAARSVVTGDVPDYAIVGGNPARVIRYRF
CCCCCEEECCCEEEEEHHEEECCEEECCCEEEEEEEEEECCCCCEEEECCCCEEEEEEEE
DDDTIARLNALAWWNWPVEQISRNLLLIGGGEIAALEAAAR
CCCHHHHHEEEEEECCCHHHCCCCEEEEECCCEEEEEECCC
>Mature Secondary Structure
MCRQIRKESTLHGPDPANPHPMKGFPQVCFIKNTIKGPNIEVGDYSYYDDPEDSAGFERN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCC
VLYHFPFIGDRLIIGKFCAIARGVKFIMNGANHQSSGFSTYPFFIFGNGWESAAPAPGTL
EEEECCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCEECCEEEEECCCCCCCCCCCCC
PYKGDTVIGNDVWIGYDTLIMPGVKVGNGAIIAARSVVTGDVPDYAIVGGNPARVIRYRF
CCCCCEEECCCEEEEEHHEEECCEEECCCEEEEEEEEEECCCCCEEEECCCCEEEEEEEE
DDDTIARLNALAWWNWPVEQISRNLLLIGGGEIAALEAAAR
CCCHHHHHEEEEEECCCHHHCCCCEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: 0.20 {glucose} 0.11 {maltose}

Km value (mM): 0.018 {acetyl-CoA}} 62 {glucose}} 40 {triethanolamine}} 90 {maltose}} [C]

Substrates: Acetyl-CoA; maltose [C]

Specific reaction: Acetyl-CoA + maltose = CoA + acetylmaltose [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8344533; 3149758 [H]