Click here to switch to the map view.

The map label for this gene is hemY [H]

Identifier: 145300739

GI number: 145300739

Start: 4164553

End: 4165716

Strand: Direct

Name: hemY [H]

Synonym: ASA_3878

Alternate gene names: 145300739

Gene position: 4164553-4165716 (Clockwise)

Preceding gene: 145300738

Following gene: 145300742

Centisome position: 88.56

GC content: 63.4

Gene sequence:

>1164_bases
ATGATTCGTCTGATTGTTCTGGTGGCCGTGATGATAGCCGGGCTGATGTTTGGCCCTGAAGCATCCGGCAACAAGGGGTA
TGTGCTGATCGCCCTGGGTAACTACACGGTAGAGTCCTCTGTCACCAGTGCCGTGATCCTGGCCGTGCTGTTCTACGGCG
CCCTGCTTGTCATCGAATGGCTACTGGGCAGGGTATTCGGTCTGCGCCGCAAGACACTGGGCTGGTACGGTTCACGCCGG
CGCCGCAAGGCCAACCAGCAGACGGTGGCAGCGACACTGGCCATGGCCGAAGGTCACTACAGCCAGGCCGAGAAGCTGAT
GCTCAAGGGCGCCAGCAACAGCGATACCCCGCTGCTCAACTACCTGAGTGCCGCCAAGGCCGCCCAGGCCCGTGGCGACG
ACGTGCGCCGGGATCAATACCTGCAAAAAGCGCAGGAGGAGAACCCCAAGGCCGAGCTGGCACTGACCTTGACCCAGACC
CAGCTGCAAATTGAGCAGGGCCAGTACGACACTGCGCTGGCCATGCTGGAATCCGTCTACGCCCTCAACCCGCGCCATCC
CATGGTGCTGGATCAGCTGCGTCAGGTACATCTGGCGCGCGAGGACTGGGCGGCCATCATCGACCTGATCCCCGTGCTGC
ACAAGGTGGGCAAGCTGACCCCCAAACAGGAAGAAGATTTGCTGCATCGGGCCTGGACCGGTCGGCTCAAGGCTGCCAGT
GACGCCCTCGAAACCCTGCGCCCTGTCTGGCAGGGTCTGCCCCGCAAGCTGCGCCAGGATCCGGATCTGCTGGCCGCCTA
CGGCGATCGCCTGCGTGAGCTCGGCGCCGACAGCGAAGCCGCCGAACTCTGGCTGGACGCGCTGCGCAAGCAGGTATCCC
CCCAGTTGCTGGCTCGCCTGCCCAAACTCAAGCTGGAGAGCTACCAGCCGGTGCTGACCCTGTTGCAGAAGATACAGGAT
CAACCGGGTGTCGAGGCAGCCCTGGCCCAGGTCTATCTGCTGGCGGGTCAACTGGACCAAGCCCAGCGCCTGCTGGAACA
GGAAGTGGCGAAGACACCTAGCGCCGCCATGTACCACGCCCTTGGCCAGGTAATGGACAAGCGCCGGCTCACCAACAAGG
CCAACGAGTATTATCGTCAGGCCCTGGCGCTGGCCGACGTCTGA

Upstream 100 bases:

>100_bases
CAGTTCACCTATCCGGATCGCTTCAAGACCCAAGCCATGCTGGAAGAGGTGCTGACCGAGCGCCTGCAACGCATTCTGGC
CAGCAACTGAGGAGGGCACC

Downstream 100 bases:

>100_bases
CCCGGCTGCCACTGACGGATACCACCAAAAAAGAGAGGCCGCGATTGCGGCCTCTCTTTTTTCTGATCTGCTCTGATTTT
ACGCCGCGGCCGGTTTATGC

Product: HemY protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MIRLIVLVAVMIAGLMFGPEASGNKGYVLIALGNYTVESSVTSAVILAVLFYGALLVIEWLLGRVFGLRRKTLGWYGSRR
RRKANQQTVAATLAMAEGHYSQAEKLMLKGASNSDTPLLNYLSAAKAAQARGDDVRRDQYLQKAQEENPKAELALTLTQT
QLQIEQGQYDTALAMLESVYALNPRHPMVLDQLRQVHLAREDWAAIIDLIPVLHKVGKLTPKQEEDLLHRAWTGRLKAAS
DALETLRPVWQGLPRKLRQDPDLLAAYGDRLRELGADSEAAELWLDALRKQVSPQLLARLPKLKLESYQPVLTLLQKIQD
QPGVEAALAQVYLLAGQLDQAQRLLEQEVAKTPSAAMYHALGQVMDKRRLTNKANEYYRQALALADV

Sequences:

>Translated_387_residues
MIRLIVLVAVMIAGLMFGPEASGNKGYVLIALGNYTVESSVTSAVILAVLFYGALLVIEWLLGRVFGLRRKTLGWYGSRR
RRKANQQTVAATLAMAEGHYSQAEKLMLKGASNSDTPLLNYLSAAKAAQARGDDVRRDQYLQKAQEENPKAELALTLTQT
QLQIEQGQYDTALAMLESVYALNPRHPMVLDQLRQVHLAREDWAAIIDLIPVLHKVGKLTPKQEEDLLHRAWTGRLKAAS
DALETLRPVWQGLPRKLRQDPDLLAAYGDRLRELGADSEAAELWLDALRKQVSPQLLARLPKLKLESYQPVLTLLQKIQD
QPGVEAALAQVYLLAGQLDQAQRLLEQEVAKTPSAAMYHALGQVMDKRRLTNKANEYYRQALALADV
>Mature_387_residues
MIRLIVLVAVMIAGLMFGPEASGNKGYVLIALGNYTVESSVTSAVILAVLFYGALLVIEWLLGRVFGLRRKTLGWYGSRR
RRKANQQTVAATLAMAEGHYSQAEKLMLKGASNSDTPLLNYLSAAKAAQARGDDVRRDQYLQKAQEENPKAELALTLTQT
QLQIEQGQYDTALAMLESVYALNPRHPMVLDQLRQVHLAREDWAAIIDLIPVLHKVGKLTPKQEEDLLHRAWTGRLKAAS
DALETLRPVWQGLPRKLRQDPDLLAAYGDRLRELGADSEAAELWLDALRKQVSPQLLARLPKLKLESYQPVLTLLQKIQD
QPGVEAALAQVYLLAGQLDQAQRLLEQEVAKTPSAAMYHALGQVMDKRRLTNKANEYYRQALALADV

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=379, Percent_Identity=32.4538258575198, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 43118; Mature: 43118

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLIVLVAVMIAGLMFGPEASGNKGYVLIALGNYTVESSVTSAVILAVLFYGALLVIEW
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
LLGRVFGLRRKTLGWYGSRRRRKANQQTVAATLAMAEGHYSQAEKLMLKGASNSDTPLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHH
YLSAAKAAQARGDDVRRDQYLQKAQEENPKAELALTLTQTQLQIEQGQYDTALAMLESVY
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHH
ALNPRHPMVLDQLRQVHLAREDWAAIIDLIPVLHKVGKLTPKQEEDLLHRAWTGRLKAAS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHH
DALETLRPVWQGLPRKLRQDPDLLAAYGDRLRELGADSEAAELWLDALRKQVSPQLLARL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHC
PKLKLESYQPVLTLLQKIQDQPGVEAALAQVYLLAGQLDQAQRLLEQEVAKTPSAAMYHA
CHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGQVMDKRRLTNKANEYYRQALALADV
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRLIVLVAVMIAGLMFGPEASGNKGYVLIALGNYTVESSVTSAVILAVLFYGALLVIEW
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
LLGRVFGLRRKTLGWYGSRRRRKANQQTVAATLAMAEGHYSQAEKLMLKGASNSDTPLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHH
YLSAAKAAQARGDDVRRDQYLQKAQEENPKAELALTLTQTQLQIEQGQYDTALAMLESVY
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHH
ALNPRHPMVLDQLRQVHLAREDWAAIIDLIPVLHKVGKLTPKQEEDLLHRAWTGRLKAAS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHH
DALETLRPVWQGLPRKLRQDPDLLAAYGDRLRELGADSEAAELWLDALRKQVSPQLLARL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHC
PKLKLESYQPVLTLLQKIQDQPGVEAALAQVYLLAGQLDQAQRLLEQEVAKTPSAAMYHA
CHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGQVMDKRRLTNKANEYYRQALALADV
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]