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The map label for this gene is metA [H]

Identifier: 145300563

GI number: 145300563

Start: 3982642

End: 3983586

Strand: Direct

Name: metA [H]

Synonym: ASA_3695

Alternate gene names: 145300563

Gene position: 3982642-3983586 (Clockwise)

Preceding gene: 145300560

Following gene: 145300565

Centisome position: 84.69

GC content: 59.15

Gene sequence:

>945_bases
ATGCCGATCAAGATCCCGGATCAGTTACCTGCCGCCGAAGTGCTGGGGCAGGAGAACATCTTCGTGATGACGGAATCCAG
GGCCGTCACCCAGAACATCCGCCCATTGCGGGTGTTGATCCTCAACCTGATGCCCAAGAAGATTGAAACCGAGATCCAGC
TGATGCGGATGCTCTCCAACTCGCCGCTGCAGGTGGACGTGGATTTGCTGCGGATCGACGATCGGGAGTCGAAGAACACG
CCTCAGGCCCATCTCGAGAACTTCTATCACGATTTCGAGCAGGTTCGCGGCAACAACTATGACGGCATGATCATCACGGG
GGCACCACTCGGGCTGGTGGAGTTCGAGGAGGTGGTCTATTGGCCGCGCATCGTCGAGATCATAGAGTGGTCCCATCAAC
ACGTGACCTCGACCCTGTTCCTCTGCTGGGCCGTACAGGCGGCGCTCAAGGCCCTGTATGGCATGGAGAAGCAGACGCAT
GGGGAGAAACTGTCCGGTGTCTATCGCCACCATCGCCTCGATGAGAACGAGCCGCTGCTGCGCGGTTTCGACGACGAGTT
CGTCGCGCCTCACTCTCGCTATGCGGCCTTCGACGGGGATCTCATCCGTGCCCACACTGACCTGCAGATCTTTGCCGAGT
CCGAGGAAGCGGGGGTCTACCTGGCGGCCACCAAGGATTGTCGTCAGGTATTTGTCACCGGCCACCCTGAATACGATGTG
CTGACCCTGGATGGAGAGTATCAGCGGGATCTGGCGGCCGGGCTCGACCCCGTCATTCCGGTCAACTACTACCCGAACAA
TGATCCTGCCCTGCCGCCGCGCGCCAGCTGGCGCAGCCACGGCCATCTGTTGTTTTCCAACTGGCTCAACTACTACGTCT
ACCAGCTCACCAGCTATCGGGTGGAAGATATCGGCAAGGTGTTTACCTACCAGCAACCCAAGTAG

Upstream 100 bases:

>100_bases
TGGGGGTGAATACAAAAGGTATCTGATGACAGGCTGGGTGGCTTTGTTATAGGCTTCTGGATGTCCAGACATATTTACCG
ATGCAGTACAGGGAGTAAGC

Downstream 100 bases:

>100_bases
GGCCAGCGGTCAGGGTCAGTCGGCCTGATCCAGCCGCGTGGCCAGGGCATCCAGCCATTGGCGATGCGCCGGCAGGGTGA
AGGCCTTGGGCCTGTGGGCC

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPIKIPDQLPAAEVLGQENIFVMTESRAVTQNIRPLRVLILNLMPKKIETEIQLMRMLSNSPLQVDVDLLRIDDRESKNT
PQAHLENFYHDFEQVRGNNYDGMIITGAPLGLVEFEEVVYWPRIVEIIEWSHQHVTSTLFLCWAVQAALKALYGMEKQTH
GEKLSGVYRHHRLDENEPLLRGFDDEFVAPHSRYAAFDGDLIRAHTDLQIFAESEEAGVYLAATKDCRQVFVTGHPEYDV
LTLDGEYQRDLAAGLDPVIPVNYYPNNDPALPPRASWRSHGHLLFSNWLNYYVYQLTSYRVEDIGKVFTYQQPK

Sequences:

>Translated_314_residues
MPIKIPDQLPAAEVLGQENIFVMTESRAVTQNIRPLRVLILNLMPKKIETEIQLMRMLSNSPLQVDVDLLRIDDRESKNT
PQAHLENFYHDFEQVRGNNYDGMIITGAPLGLVEFEEVVYWPRIVEIIEWSHQHVTSTLFLCWAVQAALKALYGMEKQTH
GEKLSGVYRHHRLDENEPLLRGFDDEFVAPHSRYAAFDGDLIRAHTDLQIFAESEEAGVYLAATKDCRQVFVTGHPEYDV
LTLDGEYQRDLAAGLDPVIPVNYYPNNDPALPPRASWRSHGHLLFSNWLNYYVYQLTSYRVEDIGKVFTYQQPK
>Mature_313_residues
PIKIPDQLPAAEVLGQENIFVMTESRAVTQNIRPLRVLILNLMPKKIETEIQLMRMLSNSPLQVDVDLLRIDDRESKNTP
QAHLENFYHDFEQVRGNNYDGMIITGAPLGLVEFEEVVYWPRIVEIIEWSHQHVTSTLFLCWAVQAALKALYGMEKQTHG
EKLSGVYRHHRLDENEPLLRGFDDEFVAPHSRYAAFDGDLIRAHTDLQIFAESEEAGVYLAATKDCRQVFVTGHPEYDVL
TLDGEYQRDLAAGLDPVIPVNYYPNNDPALPPRASWRSHGHLLFSNWLNYYVYQLTSYRVEDIGKVFTYQQPK

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=299, Percent_Identity=66.8896321070234, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36186; Mature: 36055

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIPDQLPAAEVLGQENIFVMTESRAVTQNIRPLRVLILNLMPKKIETEIQLMRMLSN
CCCCCCCCCCHHHHCCCCCEEEEECCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
SPLQVDVDLLRIDDRESKNTPQAHLENFYHDFEQVRGNNYDGMIITGAPLGLVEFEEVVY
CCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHH
WPRIVEIIEWSHQHVTSTLFLCWAVQAALKALYGMEKQTHGEKLSGVYRHHRLDENEPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCCHH
RGFDDEFVAPHSRYAAFDGDLIRAHTDLQIFAESEEAGVYLAATKDCRQVFVTGHPEYDV
CCCCCCCCCCCCCEEECCCCEEEEECCEEEEEECCCCCEEEEECCCCCEEEEECCCCEEE
LTLDGEYQRDLAAGLDPVIPVNYYPNNDPALPPRASWRSHGHLLFSNWLNYYVYQLTSYR
EEECCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VEDIGKVFTYQQPK
HHHHHHHCCCCCCC
>Mature Secondary Structure 
PIKIPDQLPAAEVLGQENIFVMTESRAVTQNIRPLRVLILNLMPKKIETEIQLMRMLSN
CCCCCCCCCHHHHCCCCCEEEEECCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
SPLQVDVDLLRIDDRESKNTPQAHLENFYHDFEQVRGNNYDGMIITGAPLGLVEFEEVVY
CCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHH
WPRIVEIIEWSHQHVTSTLFLCWAVQAALKALYGMEKQTHGEKLSGVYRHHRLDENEPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCCHH
RGFDDEFVAPHSRYAAFDGDLIRAHTDLQIFAESEEAGVYLAATKDCRQVFVTGHPEYDV
CCCCCCCCCCCCCEEECCCCEEEEECCEEEEEECCCCCEEEEECCCCCEEEEECCCCEEE
LTLDGEYQRDLAAGLDPVIPVNYYPNNDPALPPRASWRSHGHLLFSNWLNYYVYQLTSYR
EEECCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VEDIGKVFTYQQPK
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA