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The map label for this gene is yfiC [C]

Identifier: 145300504

GI number: 145300504

Start: 3925831

End: 3926541

Strand: Direct

Name: yfiC [C]

Synonym: ASA_3636

Alternate gene names: 145300504

Gene position: 3925831-3926541 (Clockwise)

Preceding gene: 145300502

Following gene: 145300505

Centisome position: 83.49

GC content: 56.4

Gene sequence:

>711_bases
ATGGGACGAAACAGCGGCTTTACCTTCAAACAGTTTCACGTCGAGCACGACCGCTGCGCCATGAAAGTCGGCACGGACGG
CATACTGCTGGGCGCCTGGGCACCGGTGGCCGAGACCCGCCGGGTACTAGACATAGGTACCGGTAGCGGCCTGGTTGCAC
TCATGCTGGCCCAACGCAGCAGATCCGACTGCATCATAGATGCGGTAGACCTGGATATGAATGCAGCGACTCAGGCCAGA
GAGAATGTGGCGGCCTCCCCCTGGGAAACCCGGATCAACATCATGGAGGGCGCCATTCAGGATTATCAGGCGACCCCCTA
TGACCTCATCGTCTCCAACCCTCCCTACTTTGGAGCAGGCCAGTCTCTGCGCGACCCTGCCAGGGCACTGGCTCGACATA
CAGGCTCCCTCGACAGCCGGGATCTGCTGGCCGCATGCGATCGCTTGCTGACCCCTGTCGGACAAGTCGCGCTGGTGTTG
CCAACCGCCATGGCCGATGAAATTTTATGCATCTCGGCAGATTATGATCTGCATGGGGTTTGTTATACAGCTGTTATCAA
CAGAGCCGGGAAAGAGGCAAATCGTGTTTTATTGCTACTTGGCAGAGGATTAAACAGGTGTGAGCAGGGTGAGATTGTGA
TCCATTCTGCTGGGGGAGCCTATTCCGACAGATACATCCAACTGACCCACCCCTTCTATTTGAAGATGTAA

Upstream 100 bases:

>100_bases
AGATTATAGGCGATTATGCCGTCGGCTCCTATGGTGACTGTGGCTTAGTCGCTATAATCGCCGACCATTTTGTGTGTAAC
TGGCATATGACGGGGGTCAG

Downstream 100 bases:

>100_bases
ATTTCGTCTTGAACTATTTTTTCACGCCATTATGCTGACTCTCAAACGAGCGCCCGCTCCAGACCAGCTCAAACCACTGG
TTGTGATGAAAAAATACGCG

Product: O-methyltransferase

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MGRNSGFTFKQFHVEHDRCAMKVGTDGILLGAWAPVAETRRVLDIGTGSGLVALMLAQRSRSDCIIDAVDLDMNAATQAR
ENVAASPWETRINIMEGAIQDYQATPYDLIVSNPPYFGAGQSLRDPARALARHTGSLDSRDLLAACDRLLTPVGQVALVL
PTAMADEILCISADYDLHGVCYTAVINRAGKEANRVLLLLGRGLNRCEQGEIVIHSAGGAYSDRYIQLTHPFYLKM

Sequences:

>Translated_236_residues
MGRNSGFTFKQFHVEHDRCAMKVGTDGILLGAWAPVAETRRVLDIGTGSGLVALMLAQRSRSDCIIDAVDLDMNAATQAR
ENVAASPWETRINIMEGAIQDYQATPYDLIVSNPPYFGAGQSLRDPARALARHTGSLDSRDLLAACDRLLTPVGQVALVL
PTAMADEILCISADYDLHGVCYTAVINRAGKEANRVLLLLGRGLNRCEQGEIVIHSAGGAYSDRYIQLTHPFYLKM
>Mature_235_residues
GRNSGFTFKQFHVEHDRCAMKVGTDGILLGAWAPVAETRRVLDIGTGSGLVALMLAQRSRSDCIIDAVDLDMNAATQARE
NVAASPWETRINIMEGAIQDYQATPYDLIVSNPPYFGAGQSLRDPARALARHTGSLDSRDLLAACDRLLTPVGQVALVLP
TAMADEILCISADYDLHGVCYTAVINRAGKEANRVLLLLGRGLNRCEQGEIVIHSAGGAYSDRYIQLTHPFYLKM

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val)

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family

Homologues:

Organism=Escherichia coli, GI87082131, Length=237, Percent_Identity=45.9915611814346, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMN6_AERS4 (A4SRS5)

Other databases:

- EMBL:   CP000644
- RefSeq:   YP_001143345.1
- ProteinModelPortal:   A4SRS5
- STRING:   A4SRS5
- GeneID:   4996186
- GenomeReviews:   CP000644_GR
- KEGG:   asa:ASA_3636
- eggNOG:   COG4123
- HOGENOM:   HBG307609
- OMA:   FKQFHIN
- PhylomeDB:   A4SRS5
- ProtClustDB:   CLSK729005
- BioCyc:   ASAL382245:ASA_3636-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01872
- InterPro:   IPR002052
- InterPro:   IPR007848
- InterPro:   IPR022882

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.55

Molecular weight: Translated: 25649; Mature: 25517

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRNSGFTFKQFHVEHDRCAMKVGTDGILLGAWAPVAETRRVLDIGTGSGLVALMLAQRS
CCCCCCCEEEEEECCCHHEEEEECCCCEEEECCCCHHHCCEEEEECCCCHHHHHHHHHCC
RSDCIIDAVDLDMNAATQARENVAASPWETRINIMEGAIQDYQATPYDLIVSNPPYFGAG
CCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
QSLRDPARALARHTGSLDSRDLLAACDRLLTPVGQVALVLPTAMADEILCISADYDLHGV
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHCCCEEEEECCCCCCHH
CYTAVINRAGKEANRVLLLLGRGLNRCEQGEIVIHSAGGAYSDRYIQLTHPFYLKM
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEECCEEEEC
>Mature Secondary Structure 
GRNSGFTFKQFHVEHDRCAMKVGTDGILLGAWAPVAETRRVLDIGTGSGLVALMLAQRS
CCCCCCEEEEEECCCHHEEEEECCCCEEEECCCCHHHCCEEEEECCCCHHHHHHHHHCC
RSDCIIDAVDLDMNAATQARENVAASPWETRINIMEGAIQDYQATPYDLIVSNPPYFGAG
CCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
QSLRDPARALARHTGSLDSRDLLAACDRLLTPVGQVALVLPTAMADEILCISADYDLHGV
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHCCCEEEEECCCCCCHH
CYTAVINRAGKEANRVLLLLGRGLNRCEQGEIVIHSAGGAYSDRYIQLTHPFYLKM
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA