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The map label for this gene is yoeA [H]

Identifier: 145300311

GI number: 145300311

Start: 3719272

End: 3720699

Strand: Direct

Name: yoeA [H]

Synonym: ASA_3433

Alternate gene names: 145300311

Gene position: 3719272-3720699 (Clockwise)

Preceding gene: 145300305

Following gene: 145300313

Centisome position: 79.09

GC content: 61.9

Gene sequence:

>1428_bases
GTGTCCCGGTCAGGAAACCGGGTTTGTGCTGCCTGCAGCCAGAACTCACTTCGCCAGATGTATAGAGACGAGCTCGTGAC
CCGACCCAACCCCCTGCTGACCGCCCCCATGACGTCCGTACTGCTGCGCATGACGGGCCCCATGATCCTCGGCATCATCG
CCATACTGGCATTCAATCTGGTCGATACCTTCTTCATCGGCATGCTGGGCACCCAGGCACTCGCCGCCATCAGCTTCACC
TTCCCGGTCACCTTCGTGGTCACCTCGCTGGCAATGGGGCTGGGGGCCGGGCTCTCCGCCGTCATCGGCCATGCCCTCGG
TCAGGGCAAACATGACGAAGCCGCCCGCATCACCACCGACTGCCTGTTTCTGGCCGTGGTGCTGGTCACGCTCCTCTCGC
TCCTGGGAGCATTCACCATACAACCCCTGTTTCGGCTGCTCGGCGCCAGCGACCAGCTGATCCGCCTTATCTATGACTAC
ATGCTTATCTGGTATCTGACCGTGCCCATGCTGGTGCTGCCCATGGTGGGCAATGCCGCCATTCGGGCCACCGGGGATAC
CAAGACGCCCAGCCTGGTGATGACGGTGGCGGGGCTGGTGAACGGCGTGCTGGATCCCCTGCTCATTTTTGGCATAGGCC
CCTTTCCCGAATGGGGGATCCGCGGGGCGGCCATCGCCACGTCGATCTCCTGGTTGATGGCCATGCTGGTCAGCCTCTAC
ATATTGCGCCATCGGGAAGGCTTGCTGCGATGGCGCCTGTCCCCTCGCCCACAATTGCTGGCCCACTGGCGCGCCTTGCT
CCACGTGGCCGTGCCTGCCTCTTTCACCAACATGCTCAACCCCCTGGCCAATGCAGTGCTGATGATCATCTTCGCAGGTC
TGGGCACCGAAGTGGTGGCCGCCTACGGCGCCGCCTCCCGGGTCGAGGCACTGCTGCTCATAGTGATGATGGCGCTCTCC
TCCGTGCTGGCCCCCTTCATCTCGCAAAACTGCGGGGCTGGCAATCCGGCCCGCGCCAGGGCCGCACTGCAATTTTGCAT
GCGCTTCGCTTTGCTGTTCCAGCTCGGGGTATACGGGCTGACCTGGTTGCTGGCACCACTTATCGCCAACCTGTTCAGCG
ATCATCCACAAGTAGTGCGCCTCATCATTCTGTATTTGCACCTGGTACCCATAGGGTATGGCTTCCAGGGCATGGTGATG
CTGCTGGCCTCGGCACTCAACGGCGTCAGGGCATCGAGCATCTCGTTTCTGTTCAACGGATTGCGGCTGTTTGTCTTCTT
GTTGCCAGGGGCCTGGCTGGGGGCGGAGCTGGGAGGGGAACAGGGAGTCTATCTGGGGATACTACTGGCAAATCTGGCAG
CGGGCACTCTGGCATGGTGGTATGCCCGCCACCGTTTCGAGCGATTGTGCCATCAGGGCAAACCCTGA

Upstream 100 bases:

>100_bases
ATTAGATATGCCTCTGATGTGGGGCGTTTTTGTTAACCCTTCAAGGGCAAATACAAAAAAAATATTTTCACGTACTATGA
ATATCTTCGATGGATCGCCC

Downstream 100 bases:

>100_bases
CAGGCACAGCTTAGCTACAGAGGCTTACTCTTTACGCTCGAATTCGCCTTCGATGGTGGTCCCGCCACGATTGACCTGAC
CCGGTTGTTCCTCGCCTGGA

Product: Na(+) driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSRSGNRVCAACSQNSLRQMYRDELVTRPNPLLTAPMTSVLLRMTGPMILGIIAILAFNLVDTFFIGMLGTQALAAISFT
FPVTFVVTSLAMGLGAGLSAVIGHALGQGKHDEAARITTDCLFLAVVLVTLLSLLGAFTIQPLFRLLGASDQLIRLIYDY
MLIWYLTVPMLVLPMVGNAAIRATGDTKTPSLVMTVAGLVNGVLDPLLIFGIGPFPEWGIRGAAIATSISWLMAMLVSLY
ILRHREGLLRWRLSPRPQLLAHWRALLHVAVPASFTNMLNPLANAVLMIIFAGLGTEVVAAYGAASRVEALLLIVMMALS
SVLAPFISQNCGAGNPARARAALQFCMRFALLFQLGVYGLTWLLAPLIANLFSDHPQVVRLIILYLHLVPIGYGFQGMVM
LLASALNGVRASSISFLFNGLRLFVFLLPGAWLGAELGGEQGVYLGILLANLAAGTLAWWYARHRFERLCHQGKP

Sequences:

>Translated_475_residues
MSRSGNRVCAACSQNSLRQMYRDELVTRPNPLLTAPMTSVLLRMTGPMILGIIAILAFNLVDTFFIGMLGTQALAAISFT
FPVTFVVTSLAMGLGAGLSAVIGHALGQGKHDEAARITTDCLFLAVVLVTLLSLLGAFTIQPLFRLLGASDQLIRLIYDY
MLIWYLTVPMLVLPMVGNAAIRATGDTKTPSLVMTVAGLVNGVLDPLLIFGIGPFPEWGIRGAAIATSISWLMAMLVSLY
ILRHREGLLRWRLSPRPQLLAHWRALLHVAVPASFTNMLNPLANAVLMIIFAGLGTEVVAAYGAASRVEALLLIVMMALS
SVLAPFISQNCGAGNPARARAALQFCMRFALLFQLGVYGLTWLLAPLIANLFSDHPQVVRLIILYLHLVPIGYGFQGMVM
LLASALNGVRASSISFLFNGLRLFVFLLPGAWLGAELGGEQGVYLGILLANLAAGTLAWWYARHRFERLCHQGKP
>Mature_474_residues
SRSGNRVCAACSQNSLRQMYRDELVTRPNPLLTAPMTSVLLRMTGPMILGIIAILAFNLVDTFFIGMLGTQALAAISFTF
PVTFVVTSLAMGLGAGLSAVIGHALGQGKHDEAARITTDCLFLAVVLVTLLSLLGAFTIQPLFRLLGASDQLIRLIYDYM
LIWYLTVPMLVLPMVGNAAIRATGDTKTPSLVMTVAGLVNGVLDPLLIFGIGPFPEWGIRGAAIATSISWLMAMLVSLYI
LRHREGLLRWRLSPRPQLLAHWRALLHVAVPASFTNMLNPLANAVLMIIFAGLGTEVVAAYGAASRVEALLLIVMMALSS
VLAPFISQNCGAGNPARARAALQFCMRFALLFQLGVYGLTWLLAPLIANLFSDHPQVVRLIILYLHLVPIGYGFQGMVML
LASALNGVRASSISFLFNGLRLFVFLLPGAWLGAELGGEQGVYLGILLANLAAGTLAWWYARHRFERLCHQGKP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=414, Percent_Identity=23.9130434782609, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320545, Length=390, Percent_Identity=22.3076923076923, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51357; Mature: 51226

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRSGNRVCAACSQNSLRQMYRDELVTRPNPLLTAPMTSVLLRMTGPMILGIIAILAFNL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]