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The map label for this gene is mcpA [H]

Identifier: 145300164

GI number: 145300164

Start: 3534850

End: 3537048

Strand: Direct

Name: mcpA [H]

Synonym: ASA_3269

Alternate gene names: 145300164

Gene position: 3534850-3537048 (Clockwise)

Preceding gene: 145300163

Following gene: 145300165

Centisome position: 75.17

GC content: 59.12

Gene sequence:

>2199_bases
ATGGCATGTCGCACAAGGATAAGGCTCATGACTCAATCATTCTTTGGCAATCTCTTCGGCAACGGCAGCGCGCATGCCTT
GTTGCAAACAGAACTGACCCAACTGATAGGCGCCACACGCACCCTGCAGCAAGGGATAGCGCAGGGTGACCTGCCAACCC
AGCTTGAACCGGGCACACTCAGCGGCCCACTGCGGGAACTCTGTCAGGAATTCAATGCCGTGATCACGCTGCTGGGGCAG
CGGCTCAGCAGCAGCCTCACTACCATCAGTGACAATCAGGCGCTCTATGACGAGAACCTGCGAGTACGCAAGGCGCTGGA
TGGCGCCTCGACCAATGTGATGATCGCCGATAACAACCTCGACATCGTCTATATGAATGAAGCCGTGCTCGCCATGCTGG
GGCAGGCGGAATCCGACATCCGCAAGGATCTGCCCAACTTCGACACCAGACAACTGATGGGCAAGAACATAGATACCTTT
CACAAGGATCCGTCCCACCAGCGCAGCATGCTGGCCAAGCTGGACAAGACCTACCGCGCGCAGATCTCGGTCGGTGGCCG
CATCTTCTCCCTCATTGCCAACCCAGTCTTCAACGACAGCGGGGAGCGACTCGGTTCAGTGGTGGAGTGGGCCGACCGGA
CCAAGGAGATCGCCATCGAAAACGAGGTGAAAGCGGCAAACACTGCGGCCAAGCTCGCCGCCGCCGAAAGCCTGCGGGTC
AAGAAGGCGCTCGATGGCGCAACTACCAACGTGATGATTGCCGACACAGACCTCAACATCATCTACATGAACGAGTCTGT
CAGGGCAATGCTGAGCGAGGCCGAGTCCGACATTAAAAAAGAGCTCTACAGCTTCAACTCTGCCACCCTGATGGGTGCCA
ACATCGACAGCTTCCACAAAAATCCCGGCCATCAACGCAGCATGCTGGCCAAGCTGAACAACACCTACCAAACCCAGATA
CTGCTCGGCGGGCGCACCTTCTCCCTCATCGCCAACCCTGTGTTTGGCGACGATGGCGAGCGGTTGGGATCCGTGGTCGA
GTGGTCGGATCGCACCAAAGAGGTCGCTATCGAGCGGGAAATGTCGGAGATAGTGCAGGCAGTGATCAAGGGCGAGCTGC
ACCGCCGCATGGACCTGACCGGCAAGAGCGGCTTCTTCCAGACACTGGGGGAAGGCATCAATCATATTGCCGAGGTAATA
GACACCAGCCTCAACGACGTCATCAGGGTGGTGCAATGCCTGGCCAGGGGCGACCTGACCCAGACGATCGAGGCCGACTA
TCCCGGTGTGTTCGGCACCACCAAGGACTCCCTCAATCAGACCATAGTCTCGCTGACCAACATAGTCACAGAAGTAAGAG
GGGCTTCTGACAACCTCTCCAGCGCCTCTGAGCAAGTCAGCGCCACCGCCCAATCCATCAGCCAGTCGAGCAGCGAGCAG
GCATCCAGCATGGAGCAGACCAGCGCCTCCATAGAGCAGATGAGTGCCAGTATCAACCAGAACACAGACAACGCCCAGAT
CACGGATGGCATGGCCAGCAAGGCCGCCAAAGAGGCGATGGAAGGGGGTGAAGCAGTCAAGCTCACGGTCGATGCCATGA
AGCAGATCGCCAAGCGGATCGGCATCATAGATGACATCGCGTACCAGACCAATCTGCTGGCCCTGAACGCCGCCATAGAG
GCGGCGCGGGCGGGAGATCATGGCAAAGGCTTTGCGGTGGTTGCCGCCGAGGTACGAAAGCTGGCGGAGCGCAGTCAGGT
GGCCGCCCAGGAGATAGGCGAGCTGGCTTCCAGCAGCGTCGACATGGCGGAAAAGGCAGGTCGCCTGCTCGACCAGATGG
TGCCCTCCATCAATAAGACCTCGGATCTGGTGCAGGAGATCAGCGCCGCCTCCGCTGAACAATCCACCGGCGTCAGCCAG
ATCAACATCGCCATGAATCAGTTAAGCCAGGTGACCCAGCAAAATGCTTCCTGCAGCGAGGAGCTGGCCGCCACCGCAGA
GGAGATGAGCAGCCAGGCCGAGCAACTGCAACTAGCCATGGAGTTCTTCACCCTGGAGCAACACAAAAGCGGCGCGAGTC
AGAAAGCCGCGCCCCCCCGTGCTGCTACGCGAGGACGATTCGTGACTGACGGCAATGGGCAGGATGGCTTCGGCGCCTCC
CCTCGCCCCCGCAACGATGGGGATTTTGTCCGGTTTTAA

Upstream 100 bases:

>100_bases
CGAACTGACCCAGCAGCAGGAACGACAGCTGGAGCACAGAGTGCAAACCCCTTAAGCAGGGTATTAAAAACAGCAAGGGT
GACGCTCACACCACACAGCA

Downstream 100 bases:

>100_bases
TCGAGGGGCCGGGTGAGCATGGCTCCCCCGCCCCAACCCTATCGCCACAGGGAGTCCGACCGTGTATCAGACCCAGTTGC
ATGATGATGAATTTGCGCAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MACRTRIRLMTQSFFGNLFGNGSAHALLQTELTQLIGATRTLQQGIAQGDLPTQLEPGTLSGPLRELCQEFNAVITLLGQ
RLSSSLTTISDNQALYDENLRVRKALDGASTNVMIADNNLDIVYMNEAVLAMLGQAESDIRKDLPNFDTRQLMGKNIDTF
HKDPSHQRSMLAKLDKTYRAQISVGGRIFSLIANPVFNDSGERLGSVVEWADRTKEIAIENEVKAANTAAKLAAAESLRV
KKALDGATTNVMIADTDLNIIYMNESVRAMLSEAESDIKKELYSFNSATLMGANIDSFHKNPGHQRSMLAKLNNTYQTQI
LLGGRTFSLIANPVFGDDGERLGSVVEWSDRTKEVAIEREMSEIVQAVIKGELHRRMDLTGKSGFFQTLGEGINHIAEVI
DTSLNDVIRVVQCLARGDLTQTIEADYPGVFGTTKDSLNQTIVSLTNIVTEVRGASDNLSSASEQVSATAQSISQSSSEQ
ASSMEQTSASIEQMSASINQNTDNAQITDGMASKAAKEAMEGGEAVKLTVDAMKQIAKRIGIIDDIAYQTNLLALNAAIE
AARAGDHGKGFAVVAAEVRKLAERSQVAAQEIGELASSSVDMAEKAGRLLDQMVPSINKTSDLVQEISAASAEQSTGVSQ
INIAMNQLSQVTQQNASCSEELAATAEEMSSQAEQLQLAMEFFTLEQHKSGASQKAAPPRAATRGRFVTDGNGQDGFGAS
PRPRNDGDFVRF

Sequences:

>Translated_732_residues
MACRTRIRLMTQSFFGNLFGNGSAHALLQTELTQLIGATRTLQQGIAQGDLPTQLEPGTLSGPLRELCQEFNAVITLLGQ
RLSSSLTTISDNQALYDENLRVRKALDGASTNVMIADNNLDIVYMNEAVLAMLGQAESDIRKDLPNFDTRQLMGKNIDTF
HKDPSHQRSMLAKLDKTYRAQISVGGRIFSLIANPVFNDSGERLGSVVEWADRTKEIAIENEVKAANTAAKLAAAESLRV
KKALDGATTNVMIADTDLNIIYMNESVRAMLSEAESDIKKELYSFNSATLMGANIDSFHKNPGHQRSMLAKLNNTYQTQI
LLGGRTFSLIANPVFGDDGERLGSVVEWSDRTKEVAIEREMSEIVQAVIKGELHRRMDLTGKSGFFQTLGEGINHIAEVI
DTSLNDVIRVVQCLARGDLTQTIEADYPGVFGTTKDSLNQTIVSLTNIVTEVRGASDNLSSASEQVSATAQSISQSSSEQ
ASSMEQTSASIEQMSASINQNTDNAQITDGMASKAAKEAMEGGEAVKLTVDAMKQIAKRIGIIDDIAYQTNLLALNAAIE
AARAGDHGKGFAVVAAEVRKLAERSQVAAQEIGELASSSVDMAEKAGRLLDQMVPSINKTSDLVQEISAASAEQSTGVSQ
INIAMNQLSQVTQQNASCSEELAATAEEMSSQAEQLQLAMEFFTLEQHKSGASQKAAPPRAATRGRFVTDGNGQDGFGAS
PRPRNDGDFVRF
>Mature_731_residues
ACRTRIRLMTQSFFGNLFGNGSAHALLQTELTQLIGATRTLQQGIAQGDLPTQLEPGTLSGPLRELCQEFNAVITLLGQR
LSSSLTTISDNQALYDENLRVRKALDGASTNVMIADNNLDIVYMNEAVLAMLGQAESDIRKDLPNFDTRQLMGKNIDTFH
KDPSHQRSMLAKLDKTYRAQISVGGRIFSLIANPVFNDSGERLGSVVEWADRTKEIAIENEVKAANTAAKLAAAESLRVK
KALDGATTNVMIADTDLNIIYMNESVRAMLSEAESDIKKELYSFNSATLMGANIDSFHKNPGHQRSMLAKLNNTYQTQIL
LGGRTFSLIANPVFGDDGERLGSVVEWSDRTKEVAIEREMSEIVQAVIKGELHRRMDLTGKSGFFQTLGEGINHIAEVID
TSLNDVIRVVQCLARGDLTQTIEADYPGVFGTTKDSLNQTIVSLTNIVTEVRGASDNLSSASEQVSATAQSISQSSSEQA
SSMEQTSASIEQMSASINQNTDNAQITDGMASKAAKEAMEGGEAVKLTVDAMKQIAKRIGIIDDIAYQTNLLALNAAIEA
ARAGDHGKGFAVVAAEVRKLAERSQVAAQEIGELASSSVDMAEKAGRLLDQMVPSINKTSDLVQEISAASAEQSTGVSQI
NIAMNQLSQVTQQNASCSEELAATAEEMSSQAEQLQLAMEFFTLEQHKSGASQKAAPPRAATRGRFVTDGNGQDGFGASP
RPRNDGDFVRF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=301, Percent_Identity=39.5348837209302, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1788195, Length=277, Percent_Identity=40.072202166065, Blast_Score=185, Evalue=9e-48,
Organism=Escherichia coli, GI1788194, Length=295, Percent_Identity=38.9830508474576, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI2367378, Length=323, Percent_Identity=38.0804953560372, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789453, Length=249, Percent_Identity=36.5461847389558, Blast_Score=149, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 78952; Mature: 78820

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACRTRIRLMTQSFFGNLFGNGSAHALLQTELTQLIGATRTLQQGIAQGDLPTQLEPGTL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SGPLRELCQEFNAVITLLGQRLSSSLTTISDNQALYDENLRVRKALDGASTNVMIADNNL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHCCCCCEEEEECCCE
DIVYMNEAVLAMLGQAESDIRKDLPNFDTRQLMGKNIDTFHKDPSHQRSMLAKLDKTYRA
EEEEECHHHHHHHCCHHHHHHHCCCCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
QISVGGRIFSLIANPVFNDSGERLGSVVEWADRTKEIAIENEVKAANTAAKLAAAESLRV
HHHCCHHHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
KKALDGATTNVMIADTDLNIIYMNESVRAMLSEAESDIKKELYSFNSATLMGANIDSFHK
HHHHCCCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHCC
NPGHQRSMLAKLNNTYQTQILLGGRTFSLIANPVFGDDGERLGSVVEWSDRTKEVAIERE
CCCHHHHHHHHHCCCEEEEEEECCCEEEHHCCCCCCCCHHHHCCHHHHCCHHHHHHHHHH
MSEIVQAVIKGELHRRMDLTGKSGFFQTLGEGINHIAEVIDTSLNDVIRVVQCLARGDLT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
QTIEADYPGVFGTTKDSLNQTIVSLTNIVTEVRGASDNLSSASEQVSATAQSISQSSSEQ
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ASSMEQTSASIEQMSASINQNTDNAQITDGMASKAAKEAMEGGEAVKLTVDAMKQIAKRI
HHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHC
GIIDDIAYQTNLLALNAAIEAARAGDHGKGFAVVAAEVRKLAERSQVAAQEIGELASSSV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DMAEKAGRLLDQMVPSINKTSDLVQEISAASAEQSTGVSQINIAMNQLSQVTQQNASCSE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCHHH
ELAATAEEMSSQAEQLQLAMEFFTLEQHKSGASQKAAPPRAATRGRFVTDGNGQDGFGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEECCCCCCCCCCC
PRPRNDGDFVRF
CCCCCCCCCCCC
>Mature Secondary Structure 
ACRTRIRLMTQSFFGNLFGNGSAHALLQTELTQLIGATRTLQQGIAQGDLPTQLEPGTL
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SGPLRELCQEFNAVITLLGQRLSSSLTTISDNQALYDENLRVRKALDGASTNVMIADNNL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHCCCCCEEEEECCCE
DIVYMNEAVLAMLGQAESDIRKDLPNFDTRQLMGKNIDTFHKDPSHQRSMLAKLDKTYRA
EEEEECHHHHHHHCCHHHHHHHCCCCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
QISVGGRIFSLIANPVFNDSGERLGSVVEWADRTKEIAIENEVKAANTAAKLAAAESLRV
HHHCCHHHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
KKALDGATTNVMIADTDLNIIYMNESVRAMLSEAESDIKKELYSFNSATLMGANIDSFHK
HHHHCCCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHCC
NPGHQRSMLAKLNNTYQTQILLGGRTFSLIANPVFGDDGERLGSVVEWSDRTKEVAIERE
CCCHHHHHHHHHCCCEEEEEEECCCEEEHHCCCCCCCCHHHHCCHHHHCCHHHHHHHHHH
MSEIVQAVIKGELHRRMDLTGKSGFFQTLGEGINHIAEVIDTSLNDVIRVVQCLARGDLT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
QTIEADYPGVFGTTKDSLNQTIVSLTNIVTEVRGASDNLSSASEQVSATAQSISQSSSEQ
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ASSMEQTSASIEQMSASINQNTDNAQITDGMASKAAKEAMEGGEAVKLTVDAMKQIAKRI
HHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHC
GIIDDIAYQTNLLALNAAIEAARAGDHGKGFAVVAAEVRKLAERSQVAAQEIGELASSSV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DMAEKAGRLLDQMVPSINKTSDLVQEISAASAEQSTGVSQINIAMNQLSQVTQQNASCSE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCHHH
ELAATAEEMSSQAEQLQLAMEFFTLEQHKSGASQKAAPPRAATRGRFVTDGNGQDGFGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEECCCCCCCCCCC
PRPRNDGDFVRF
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]