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The map label for this gene is fadE [H]

Identifier: 145299709

GI number: 145299709

Start: 2981205

End: 2983661

Strand: Direct

Name: fadE [H]

Synonym: ASA_2784

Alternate gene names: 145299709

Gene position: 2981205-2983661 (Clockwise)

Preceding gene: 145299705

Following gene: 145299710

Centisome position: 63.4

GC content: 61.05

Gene sequence:

>2457_bases
ATGACGACGACCCTCACTCTGCTCGGGGTGATCCTGGTGATCGGCGCCATGGCTTATCGCCGGGCGTCTCTGTTCACATC
CACGCTTGCCACGGCCGCCGCCCTGGTCGCTGGCACCCTCTATGGCAATGTCCCCCTGCTGGTGTGGGCACTGTTCGCCA
TGGTTGCCATCCCCCTCAACCTGGTGGATTTTCGCCGCAATCAGCTGACCAAGCCGCTGTTCAAGATCTACAAGTCGATC
ATGCCGGAGATGTCCCGCACCGAGAAGGAAGCCATCGAAGCCGGGACCACCTGGTGGGAAGCGGACCTGTTCGCCGGCAA
CCCGAACTGGAAGAAGCTGCACGCCATCCCGGTCAGCGTTCTATCAACCGAAGAGCAAGCCTTCATGGATGGCCCGGTTG
AAAACGTCTGCCGCATGGTCAACGACTGGGAAGTGACTCACGAGCGGGCCGATCTCTCCCCCGAGGTGTGGCAATACCTG
AAGGACAACAAGTTCTTCGCCATGATCATCAAGAAGAAATACGGTGGTCTGGAATTCTCCGCCTATGCCCAGTCCTGTGT
GCTGCAAAAACTGTGTGGCGCCAGCGCCGTGCTGGCCTCCACAGTAGGCGTCCCCAACTCCCTTGGCCCGGGTGAACTGC
TGCAACACTACGGCACCGATGAGCAGAAAGACCACTACCTGCCCCGCCTGGCGGTAGGCAAAGAGATCCCCTGCTTCGCC
CTGACCAGCCCGGAAGCGGGTTCCGACGCCGGCTCCATTCCCGACTTCGGCATTATCTGCAAGGGTGAATGGGAAGGGGA
AGAGGTGCTTGGCATGCGCCTGACCTGGAACAAGCGCTACATCACGCTCGCCCCTATTGCTACCGTGCTGGGTCTGGCCT
TCAAGCTGCGCGACCCGGATCACCTGCTGGGTGACGAAGAGGAGCTGGGCATCACCTGTGCCCTGATCCCGACCCACATC
AAAGGGGTCGAGATAGGCCGTCGTCACTTCCCGCTCAACGTGCCGTTCCAGAATGGTCCGACCCGTGGCGACAATGTGTT
TGTACCGCTCGACTTCATCATAGGTGGCCCGGCCATGGCCGGTCAGGGCTGGCGCATGCTGGTCGAATGCCTCTCGGTTG
GCCGCGGTATCACGTTGCCCTCCAACAGCACGGGCGGCGTCAAGATGCTGGCCCTGGCGACCGGCGCCTACAGCCGCATC
CGCCGCCAGTTCAAGCTGCCCATCGGCAAGATGGAAGGCATTGAAGAGCCACTGGCCCGTCTCGGTGGCAACGCCTACAT
AATGGGCGCTGCCGCCAACCTGACAGTGACCGGTATCGATCTGGGGGAAAAACCCTCGGTCATCTCCGCCATCGTCAAAT
ACCACCTCACCGACCGTGCCCAGAAGTGCATCATAGATGCCATGGACATCCACGGTGGCAAGGCCATCTGCATGGGCCCG
AACAACTATCTGGCTCGTGGCTATCAGGGAGCCCCGATCGCAGTGCCAGTAGAAGGGGCCAACATCCTGACCCGCAGCAT
GATCATCTACGGTCAGGGCGCCATCCGCTGCCACCCCTATGTCCTGCCGGAGATGCTGGCAGCCAGCCATCCGGACAAGG
AACAAGCGCTGAAGGATTTCGACAAGGCCATGTTCAGCCACGTCGGTTTTGCCATCAGCAACCTGGTGCGCAGTTTCTGG
CTGGGCTTGACCGGTGCTCGCTTCGCCGCAGCCCCTTACAAGGATCAGACCAAGGGCTATTACCAGCAGCTCTCCCGCCT
CTCGGCCAACCTGGCCTTCCTGTCAGACATGGCCATGGGCACCTTGGGCGGCGAGCTCAAGCGCAAGGAGCGTGTCTCCG
CTCGCCTGGGCGACGTGTTGAGTCAGCTCTACCTCGCCTCAAGTGCCCTCAAGCGCTATCAGGATGAGGGTCGTCAGCAG
GCGGATCTGCCACTGCTGCACTGGGCACTGCAAGATGCCATGTTCAAGGCGCAAGAGGCGATCGACGAGCTGTTGCGCAA
CTTCCCGAACCGCTGGATTGGCCTTGCGCTGCGCGTCATAGTGCTGCCCCTTGGCCGTGACATGAAGCGCCCGAGCGACA
AGCTGGACCAGCAAGTAGCCCGCCTGCTGCAAACGCCGAGCGAGACTCGCAGCCGACTGGCACAGGGTCAATACCTGACC
CGCGAAGAGGGTAACCCCTTCGGCTTGCTGGAACAGGCGCTGGATGATGTGCTGGCGGCCGAACCGCTGTTTGACAAAGT
ATGCAAAGCTGACGGTATCAAGCGTCTGTTTATGCAACTGGACAAGGTAGCGGATGCGGGTCTGGCGCTCGGTGTGCTCA
ACCAGAATGAGGCCGACTTGCTGCGCCGGGCCGAAGAGAGCCGCCTGCGAACCATCAACGTCGATGATTTCGACCCCATC
GACCTGGTTGCCAACAAGACCCTGTTCGAACCATCGGCCTATCACAGAGCAGCCTGA

Upstream 100 bases:

>100_bases
GCGTATGAATTACAACAGGGGCCATGTCCAACAGGTCAGACCTCTGGATCAGTTAATCTACTGCTTAGCCAACTTCGGCA
ACTCATGCAAGGAGCGAAAA

Downstream 100 bases:

>100_bases
TACGCAGAAAACGAACCTGACGCCTCCCATGTGGAGGCGTTTTTTATGGACCTGGATCACGATGACAACAAAGAGATTTC
ACAGATCAAATTTTATTTCT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 818; Mature: 817

Protein sequence:

>818_residues
MTTTLTLLGVILVIGAMAYRRASLFTSTLATAAALVAGTLYGNVPLLVWALFAMVAIPLNLVDFRRNQLTKPLFKIYKSI
MPEMSRTEKEAIEAGTTWWEADLFAGNPNWKKLHAIPVSVLSTEEQAFMDGPVENVCRMVNDWEVTHERADLSPEVWQYL
KDNKFFAMIIKKKYGGLEFSAYAQSCVLQKLCGASAVLASTVGVPNSLGPGELLQHYGTDEQKDHYLPRLAVGKEIPCFA
LTSPEAGSDAGSIPDFGIICKGEWEGEEVLGMRLTWNKRYITLAPIATVLGLAFKLRDPDHLLGDEEELGITCALIPTHI
KGVEIGRRHFPLNVPFQNGPTRGDNVFVPLDFIIGGPAMAGQGWRMLVECLSVGRGITLPSNSTGGVKMLALATGAYSRI
RRQFKLPIGKMEGIEEPLARLGGNAYIMGAAANLTVTGIDLGEKPSVISAIVKYHLTDRAQKCIIDAMDIHGGKAICMGP
NNYLARGYQGAPIAVPVEGANILTRSMIIYGQGAIRCHPYVLPEMLAASHPDKEQALKDFDKAMFSHVGFAISNLVRSFW
LGLTGARFAAAPYKDQTKGYYQQLSRLSANLAFLSDMAMGTLGGELKRKERVSARLGDVLSQLYLASSALKRYQDEGRQQ
ADLPLLHWALQDAMFKAQEAIDELLRNFPNRWIGLALRVIVLPLGRDMKRPSDKLDQQVARLLQTPSETRSRLAQGQYLT
REEGNPFGLLEQALDDVLAAEPLFDKVCKADGIKRLFMQLDKVADAGLALGVLNQNEADLLRRAEESRLRTINVDDFDPI
DLVANKTLFEPSAYHRAA

Sequences:

>Translated_818_residues
MTTTLTLLGVILVIGAMAYRRASLFTSTLATAAALVAGTLYGNVPLLVWALFAMVAIPLNLVDFRRNQLTKPLFKIYKSI
MPEMSRTEKEAIEAGTTWWEADLFAGNPNWKKLHAIPVSVLSTEEQAFMDGPVENVCRMVNDWEVTHERADLSPEVWQYL
KDNKFFAMIIKKKYGGLEFSAYAQSCVLQKLCGASAVLASTVGVPNSLGPGELLQHYGTDEQKDHYLPRLAVGKEIPCFA
LTSPEAGSDAGSIPDFGIICKGEWEGEEVLGMRLTWNKRYITLAPIATVLGLAFKLRDPDHLLGDEEELGITCALIPTHI
KGVEIGRRHFPLNVPFQNGPTRGDNVFVPLDFIIGGPAMAGQGWRMLVECLSVGRGITLPSNSTGGVKMLALATGAYSRI
RRQFKLPIGKMEGIEEPLARLGGNAYIMGAAANLTVTGIDLGEKPSVISAIVKYHLTDRAQKCIIDAMDIHGGKAICMGP
NNYLARGYQGAPIAVPVEGANILTRSMIIYGQGAIRCHPYVLPEMLAASHPDKEQALKDFDKAMFSHVGFAISNLVRSFW
LGLTGARFAAAPYKDQTKGYYQQLSRLSANLAFLSDMAMGTLGGELKRKERVSARLGDVLSQLYLASSALKRYQDEGRQQ
ADLPLLHWALQDAMFKAQEAIDELLRNFPNRWIGLALRVIVLPLGRDMKRPSDKLDQQVARLLQTPSETRSRLAQGQYLT
REEGNPFGLLEQALDDVLAAEPLFDKVCKADGIKRLFMQLDKVADAGLALGVLNQNEADLLRRAEESRLRTINVDDFDPI
DLVANKTLFEPSAYHRAA
>Mature_817_residues
TTTLTLLGVILVIGAMAYRRASLFTSTLATAAALVAGTLYGNVPLLVWALFAMVAIPLNLVDFRRNQLTKPLFKIYKSIM
PEMSRTEKEAIEAGTTWWEADLFAGNPNWKKLHAIPVSVLSTEEQAFMDGPVENVCRMVNDWEVTHERADLSPEVWQYLK
DNKFFAMIIKKKYGGLEFSAYAQSCVLQKLCGASAVLASTVGVPNSLGPGELLQHYGTDEQKDHYLPRLAVGKEIPCFAL
TSPEAGSDAGSIPDFGIICKGEWEGEEVLGMRLTWNKRYITLAPIATVLGLAFKLRDPDHLLGDEEELGITCALIPTHIK
GVEIGRRHFPLNVPFQNGPTRGDNVFVPLDFIIGGPAMAGQGWRMLVECLSVGRGITLPSNSTGGVKMLALATGAYSRIR
RQFKLPIGKMEGIEEPLARLGGNAYIMGAAANLTVTGIDLGEKPSVISAIVKYHLTDRAQKCIIDAMDIHGGKAICMGPN
NYLARGYQGAPIAVPVEGANILTRSMIIYGQGAIRCHPYVLPEMLAASHPDKEQALKDFDKAMFSHVGFAISNLVRSFWL
GLTGARFAAAPYKDQTKGYYQQLSRLSANLAFLSDMAMGTLGGELKRKERVSARLGDVLSQLYLASSALKRYQDEGRQQA
DLPLLHWALQDAMFKAQEAIDELLRNFPNRWIGLALRVIVLPLGRDMKRPSDKLDQQVARLLQTPSETRSRLAQGQYLTR
EEGNPFGLLEQALDDVLAAEPLFDKVCKADGIKRLFMQLDKVADAGLALGVLNQNEADLLRRAEESRLRTINVDDFDPID
LVANKTLFEPSAYHRAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=28.4595300261097, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI4557235, Length=407, Percent_Identity=25.5528255528256, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=25.9067357512953, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI87081702, Length=798, Percent_Identity=66.4160401002506, Blast_Score=1111, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=357, Percent_Identity=26.0504201680672, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=331, Percent_Identity=25.6797583081571, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=318, Percent_Identity=22.9559748427673, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363737, Length=441, Percent_Identity=24.9433106575964, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646207, Length=355, Percent_Identity=25.0704225352113, Blast_Score=74, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89920; Mature: 89789

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLTLLGVILVIGAMAYRRASLFTSTLATAAALVAGTLYGNVPLLVWALFAMVAIPLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVDFRRNQLTKPLFKIYKSIMPEMSRTEKEAIEAGTTWWEADLFAGNPNWKKLHAIPVSV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECEEECCCCCCCEEEEEEHHH
LSTEEQAFMDGPVENVCRMVNDWEVTHERADLSPEVWQYLKDNKFFAMIIKKKYGGLEFS
HCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEHHCCCCCHH
AYAQSCVLQKLCGASAVLASTVGVPNSLGPGELLQHYGTDEQKDHYLPRLAVGKEIPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEE
LTSPEAGSDAGSIPDFGIICKGEWEGEEVLGMRLTWNKRYITLAPIATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCH
HLLGDEEELGITCALIPTHIKGVEIGRRHFPLNVPFQNGPTRGDNVFVPLDFIIGGPAMA
HHCCCCHHCCEEEEEECCCCCCEECCCCCCCEECCCCCCCCCCCEEEEEEHHEECCCCCC
GQGWRMLVECLSVGRGITLPSNSTGGVKMLALATGAYSRIRRQFKLPIGKMEGIEEPLAR
CCHHHHHHHHHHCCCCEECCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHCCHHHHHHH
LGGNAYIMGAAANLTVTGIDLGEKPSVISAIVKYHLTDRAQKCIIDAMDIHGGKAICMGP
HCCCEEEEEEECEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
NNYLARGYQGAPIAVPVEGANILTRSMIIYGQGAIRCHPYVLPEMLAASHPDKEQALKDF
CHHHHCCCCCCCEEEECCCCHHHHHEEEEEECCCEEECCHHHHHHHHCCCCCHHHHHHHH
DKAMFSHVGFAISNLVRSFWLGLTGARFAAAPYKDQTKGYYQQLSRLSANLAFLSDMAMG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGELKRKERVSARLGDVLSQLYLASSALKRYQDEGRQQADLPLLHWALQDAMFKAQEA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IDELLRNFPNRWIGLALRVIVLPLGRDMKRPSDKLDQQVARLLQTPSETRSRLAQGQYLT
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEE
REEGNPFGLLEQALDDVLAAEPLFDKVCKADGIKRLFMQLDKVADAGLALGVLNQNEADL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHH
LRRAEESRLRTINVDDFDPIDLVANKTLFEPSAYHRAA
HHHHHHHHCEEECCCCCCCHHHHHCCCCCCCCHHCCCC
>Mature Secondary Structure 
TTTLTLLGVILVIGAMAYRRASLFTSTLATAAALVAGTLYGNVPLLVWALFAMVAIPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVDFRRNQLTKPLFKIYKSIMPEMSRTEKEAIEAGTTWWEADLFAGNPNWKKLHAIPVSV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECEEECCCCCCCEEEEEEHHH
LSTEEQAFMDGPVENVCRMVNDWEVTHERADLSPEVWQYLKDNKFFAMIIKKKYGGLEFS
HCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEHHCCCCCHH
AYAQSCVLQKLCGASAVLASTVGVPNSLGPGELLQHYGTDEQKDHYLPRLAVGKEIPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEE
LTSPEAGSDAGSIPDFGIICKGEWEGEEVLGMRLTWNKRYITLAPIATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCH
HLLGDEEELGITCALIPTHIKGVEIGRRHFPLNVPFQNGPTRGDNVFVPLDFIIGGPAMA
HHCCCCHHCCEEEEEECCCCCCEECCCCCCCEECCCCCCCCCCCEEEEEEHHEECCCCCC
GQGWRMLVECLSVGRGITLPSNSTGGVKMLALATGAYSRIRRQFKLPIGKMEGIEEPLAR
CCHHHHHHHHHHCCCCEECCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHCCHHHHHHH
LGGNAYIMGAAANLTVTGIDLGEKPSVISAIVKYHLTDRAQKCIIDAMDIHGGKAICMGP
HCCCEEEEEEECEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
NNYLARGYQGAPIAVPVEGANILTRSMIIYGQGAIRCHPYVLPEMLAASHPDKEQALKDF
CHHHHCCCCCCCEEEECCCCHHHHHEEEEEECCCEEECCHHHHHHHHCCCCCHHHHHHHH
DKAMFSHVGFAISNLVRSFWLGLTGARFAAAPYKDQTKGYYQQLSRLSANLAFLSDMAMG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGELKRKERVSARLGDVLSQLYLASSALKRYQDEGRQQADLPLLHWALQDAMFKAQEA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IDELLRNFPNRWIGLALRVIVLPLGRDMKRPSDKLDQQVARLLQTPSETRSRLAQGQYLT
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEE
REEGNPFGLLEQALDDVLAAEPLFDKVCKADGIKRLFMQLDKVADAGLALGVLNQNEADL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHH
LRRAEESRLRTINVDDFDPIDLVANKTLFEPSAYHRAA
HHHHHHHHCEEECCCCCCCHHHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]