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The map label for this gene is mtnN [H]

Identifier: 145299582

GI number: 145299582

Start: 2838705

End: 2839397

Strand: Direct

Name: mtnN [H]

Synonym: ASA_2653

Alternate gene names: 145299582

Gene position: 2838705-2839397 (Clockwise)

Preceding gene: 145299581

Following gene: 145299583

Centisome position: 60.37

GC content: 58.01

Gene sequence:

>693_bases
ATGAAAGTAGGTATTATCGGCGCCATGGAACAGGAAGTGGCCCTGCTGCGCAGCCAGATGAACGAGCCAACCACGCTGCA
ACTGGGCGGCTGCGAATTCTATCAAGGCAAGCTGGCAGGCAAAGAGGTGATCCTGACTCGCTCCGGCATCGGTAAGGTCG
CCGCCAGTGTCGCCACCAGCCTGCTGCTGGAAAAATTTGCCCCGGATTGTGTCATCAACACAGGCTCAGCTGGCGGCTTC
GCTCAGGATCTGCACATCGGTGATATGGTCATCGCCGATGAGATGCGCTTTCACGATGTGGACGTGACCGCCTTTGGTTA
TGAGATGGGCCAGATGGCACAGCAACCTGCCGCCTTCCCCTGCGATGGGAAACTGATCGCGGTGGCACAGGATTGCATCG
CCGAGCAAGGCAAGCATCAGACCAAAGTTGGCCTCATCTGCACCGGTGATCAGTTCATGTGCAAACCAGACGCCATCGCC
AAGGCCCGTGCCGATTTCCCGCAGATGCTGGCGGTCGAAATGGAAGGGGCCGCCATCGGCCAGGTGTGCCACATGTTCAA
GGTGCCCTATCTGGTGGTGCGCGCCATGTCAGACATCGCCGGCAAGGAACAGGTTGAATCCTTCGATGCTTTCATCGAGG
TGGCGGGCCAGCATTCTGCCGAGATGATCATCAAGATGCTCGGCAAACTGTGA

Upstream 100 bases:

>100_bases
ATCTTTCCCCGCGTCATCTGAATGCTCGGCGCCATCACCAACTTTTGTTATGATCCACAACAACTTATTCGGCCGTGCGG
CCATCGAGACGAGGTGAGTG

Downstream 100 bases:

>100_bases
TCGACCTCGCCACACTGGAACACATGGCCGCCACTCCGGCGGCCATTTTGCTCGGGGCCGTGCTGCTGGAAGCCATACTG
CCCTGGCCTGCCCAGTTCAG

Product: MTA/SAH nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKVGIIGAMEQEVALLRSQMNEPTTLQLGGCEFYQGKLAGKEVILTRSGIGKVAASVATSLLLEKFAPDCVINTGSAGGF
AQDLHIGDMVIADEMRFHDVDVTAFGYEMGQMAQQPAAFPCDGKLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIA
KARADFPQMLAVEMEGAAIGQVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGQHSAEMIIKMLGKL

Sequences:

>Translated_230_residues
MKVGIIGAMEQEVALLRSQMNEPTTLQLGGCEFYQGKLAGKEVILTRSGIGKVAASVATSLLLEKFAPDCVINTGSAGGF
AQDLHIGDMVIADEMRFHDVDVTAFGYEMGQMAQQPAAFPCDGKLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIA
KARADFPQMLAVEMEGAAIGQVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGQHSAEMIIKMLGKL
>Mature_230_residues
MKVGIIGAMEQEVALLRSQMNEPTTLQLGGCEFYQGKLAGKEVILTRSGIGKVAASVATSLLLEKFAPDCVINTGSAGGF
AQDLHIGDMVIADEMRFHDVDVTAFGYEMGQMAQQPAAFPCDGKLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIA
KARADFPQMLAVEMEGAAIGQVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGQHSAEMIIKMLGKL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=53.9130434782609, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24622; Mature: 24622

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIIGAMEQEVALLRSQMNEPTTLQLGGCEFYQGKLAGKEVILTRSGIGKVAASVATS
CCEEEECHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCCCEEEEECCCHHHHHHHHHHH
LLLEKFAPDCVINTGSAGGFAQDLHIGDMVIADEMRFHDVDVTAFGYEMGQMAQQPAAFP
HHHHHHCCCEEEECCCCCCCCHHCCCCCEEEECCCEEEECCEEEHHHHHHHHHCCCCCCC
CDGKLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIAKARADFPQMLAVEMEGAAIG
CCCCEEHHHHHHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHCCCHHHEEEEECCHHHH
QVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGQHSAEMIIKMLGKL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKVGIIGAMEQEVALLRSQMNEPTTLQLGGCEFYQGKLAGKEVILTRSGIGKVAASVATS
CCEEEECHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCCCEEEEECCCHHHHHHHHHHH
LLLEKFAPDCVINTGSAGGFAQDLHIGDMVIADEMRFHDVDVTAFGYEMGQMAQQPAAFP
HHHHHHCCCEEEECCCCCCCCHHCCCCCEEEECCCEEEECCEEEHHHHHHHHHCCCCCCC
CDGKLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIAKARADFPQMLAVEMEGAAIG
CCCCEEHHHHHHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHCCCHHHEEEEECCHHHH
QVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGQHSAEMIIKMLGKL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA