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The map label for this gene is sbcB [H]

Identifier: 145299357

GI number: 145299357

Start: 2566684

End: 2568111

Strand: Direct

Name: sbcB [H]

Synonym: ASA_2405

Alternate gene names: 145299357

Gene position: 2566684-2568111 (Clockwise)

Preceding gene: 145299356

Following gene: 145299358

Centisome position: 54.58

GC content: 59.73

Gene sequence:

>1428_bases
ATGAGCAAAACAGCACAATCCGGCATTGAGCCCACCTTCTACTTCCACGATTACGAGACCTTCGGGATCAGTCCGGCGAA
GGACAGGCCGTCGCAGTTTGCCGGTATTCGTACCGATGCAGATTTCAACATCATCGGCGAGCCACTGGTCATCTATTGCA
AGCCGCCGGCGGATTATCTGCCGGATCCGGAGGCGTGCCTCATCACTGGCATCACGCCGCAAAAGGCGATGAAAGACGGA
CTGTGCGAGGCAGATTTCATCCGCCAGATCCACGAGCAGTTCGCTACACCGAATACCTGCGTGCTGGGCTACAACAGTAT
CCGCTTCGATGACGAGGTGACCCGCTACACCCTCTATCGCAACTTCTATGACCCTTACGCCTACGCCTGGCAAAACGGCA
ACTCCCGCTGGGATATCCTCGACATGCTGCGGGCCTGCTATGCCCTGCGCCCGGAGGGGATCGAGTGGGCCTTTGATGAG
GAGGGCAAACCAAGTTTTCGTCTCGAAAAGCTCACGGTAGCCAACGGTGTATCCCACGCCAATGCCCACGATGCGCTCTC
CGATGTGCTGGCCACCATAGAGATGGCCAAGCTGGTGAAAAAGGCCCAGCCCAAGCTGTTTGAGTACCTGTTTACCCTGC
GCAACAAGAACAAGGTCAAGGCGCTCATCGATGTGGTGACCATGAAGCCGCTGGTCCACGTCTCCGGCATGTTCTCCCCC
TGGCAGGGGTGCGTTAGCTGGATATCGCCACTCGCCTGGCACCCCACCAACCAGAATGCGGTGATCATGGTGGATTTGAC
CCGCGACCCGACCCCGCTCATCGAGCTTTCCAGCGAGGAGATCCGCGAGCGGCTCTATACCCGCAAGGACGAGCTGGGGG
ATCTGGCCGCCATTCCGGTGAAACTGGTGCACATCAACAAATGCCGTGTGCTGGCGCCAGCCGCCACCCTGACACCGGAA
CGTGCCGATGAGCTCACCATCGACCGGGAGCAGTGCCGCAAGAGCCTGAACCTGCTGCGCGCTCACCCCGAGGTGCGTGA
AAAACTGGTGGAGGTGTTCAATCAGGAGTTCGAGGGCAGCAATGACCCGGACCCCGATACCCAGCTCTACGCCGGTTTCT
TCGGCCACGGCGACAAGTCCACCATGGATCTGGTGCGCGCTACCCCGGCCGACCTGCTGGGTGAGCGTGAGTTTGCCTTC
ACAGATGCGCGGCTGCCAGAGATGCTGTTCCGCTACCGCGCCCGCAACTGGCCCCATACCCTGAGCGAGGCGGAGCAAAA
ACGCTGGCGTCTGCACTGCAGCGACTATTTCAGCCGCCGCCTGCCGGACTATGCCCCTCGTCTCGAGGCACTGGCGGAGC
AGAATCAGGGGAACGAACGGAACTTTGCGATTCTGAAGAGTCTCTATCGCTACCTCGAAGATCTATGA

Upstream 100 bases:

>100_bases
CCTGCGCTATGGTTTACCATGCAGGCAATTGTGGTGCAGGGCACCGCTCACCCAGGTGCTTTGGCGCCGTCGCCATCCCG
GACACCCTATCTCGGAACTT

Downstream 100 bases:

>100_bases
GATGTGATCGGTTTCACAGTTAAATGACTGTATGCTCCCCTCACCCCATTCATAATGGGCAGGGGAGTAAAGACTCCCGA
AATTTCAACTATTTGTGCAC

Product: exodeoxyribonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSKTAQSGIEPTFYFHDYETFGISPAKDRPSQFAGIRTDADFNIIGEPLVIYCKPPADYLPDPEACLITGITPQKAMKDG
LCEADFIRQIHEQFATPNTCVLGYNSIRFDDEVTRYTLYRNFYDPYAYAWQNGNSRWDILDMLRACYALRPEGIEWAFDE
EGKPSFRLEKLTVANGVSHANAHDALSDVLATIEMAKLVKKAQPKLFEYLFTLRNKNKVKALIDVVTMKPLVHVSGMFSP
WQGCVSWISPLAWHPTNQNAVIMVDLTRDPTPLIELSSEEIRERLYTRKDELGDLAAIPVKLVHINKCRVLAPAATLTPE
RADELTIDREQCRKSLNLLRAHPEVREKLVEVFNQEFEGSNDPDPDTQLYAGFFGHGDKSTMDLVRATPADLLGEREFAF
TDARLPEMLFRYRARNWPHTLSEAEQKRWRLHCSDYFSRRLPDYAPRLEALAEQNQGNERNFAILKSLYRYLEDL

Sequences:

>Translated_475_residues
MSKTAQSGIEPTFYFHDYETFGISPAKDRPSQFAGIRTDADFNIIGEPLVIYCKPPADYLPDPEACLITGITPQKAMKDG
LCEADFIRQIHEQFATPNTCVLGYNSIRFDDEVTRYTLYRNFYDPYAYAWQNGNSRWDILDMLRACYALRPEGIEWAFDE
EGKPSFRLEKLTVANGVSHANAHDALSDVLATIEMAKLVKKAQPKLFEYLFTLRNKNKVKALIDVVTMKPLVHVSGMFSP
WQGCVSWISPLAWHPTNQNAVIMVDLTRDPTPLIELSSEEIRERLYTRKDELGDLAAIPVKLVHINKCRVLAPAATLTPE
RADELTIDREQCRKSLNLLRAHPEVREKLVEVFNQEFEGSNDPDPDTQLYAGFFGHGDKSTMDLVRATPADLLGEREFAF
TDARLPEMLFRYRARNWPHTLSEAEQKRWRLHCSDYFSRRLPDYAPRLEALAEQNQGNERNFAILKSLYRYLEDL
>Mature_474_residues
SKTAQSGIEPTFYFHDYETFGISPAKDRPSQFAGIRTDADFNIIGEPLVIYCKPPADYLPDPEACLITGITPQKAMKDGL
CEADFIRQIHEQFATPNTCVLGYNSIRFDDEVTRYTLYRNFYDPYAYAWQNGNSRWDILDMLRACYALRPEGIEWAFDEE
GKPSFRLEKLTVANGVSHANAHDALSDVLATIEMAKLVKKAQPKLFEYLFTLRNKNKVKALIDVVTMKPLVHVSGMFSPW
QGCVSWISPLAWHPTNQNAVIMVDLTRDPTPLIELSSEEIRERLYTRKDELGDLAAIPVKLVHINKCRVLAPAATLTPER
ADELTIDREQCRKSLNLLRAHPEVREKLVEVFNQEFEGSNDPDPDTQLYAGFFGHGDKSTMDLVRATPADLLGEREFAFT
DARLPEMLFRYRARNWPHTLSEAEQKRWRLHCSDYFSRRLPDYAPRLEALAEQNQGNERNFAILKSLYRYLEDL

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=467, Percent_Identity=58.2441113490364, Blast_Score=561, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54529; Mature: 54398

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAQSGIEPTFYFHDYETFGISPAKDRPSQFAGIRTDADFNIIGEPLVIYCKPPADYL
CCCCCHHCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCEEECCCEEEEECCCCCCC
PDPEACLITGITPQKAMKDGLCEADFIRQIHEQFATPNTCVLGYNSIRFDDEVTRYTLYR
CCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHHHH
NFYDPYAYAWQNGNSRWDILDMLRACYALRPEGIEWAFDEEGKPSFRLEKLTVANGVSHA
HCCCCHHEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCC
NAHDALSDVLATIEMAKLVKKAQPKLFEYLFTLRNKNKVKALIDVVTMKPLVHVSGMFSP
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCH
WQGCVSWISPLAWHPTNQNAVIMVDLTRDPTPLIELSSEEIRERLYTRKDELGDLAAIPV
HHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCCEEECCE
KLVHINKCRVLAPAATLTPERADELTIDREQCRKSLNLLRAHPEVREKLVEVFNQEFEGS
EEEEECCCEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
NDPDPDTQLYAGFFGHGDKSTMDLVRATPADLLGEREFAFTDARLPEMLFRYRARNWPHT
CCCCCCHHEEEHHHCCCCCHHHHHHHCCCHHHHCCCCCEECHHHHHHHHHHHHHCCCCCH
LSEAEQKRWRLHCSDYFSRRLPDYAPRLEALAEQNQGNERNFAILKSLYRYLEDL
HHHHHHHHHEECHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKTAQSGIEPTFYFHDYETFGISPAKDRPSQFAGIRTDADFNIIGEPLVIYCKPPADYL
CCCCHHCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCEEECCCEEEEECCCCCCC
PDPEACLITGITPQKAMKDGLCEADFIRQIHEQFATPNTCVLGYNSIRFDDEVTRYTLYR
CCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHHHH
NFYDPYAYAWQNGNSRWDILDMLRACYALRPEGIEWAFDEEGKPSFRLEKLTVANGVSHA
HCCCCHHEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCC
NAHDALSDVLATIEMAKLVKKAQPKLFEYLFTLRNKNKVKALIDVVTMKPLVHVSGMFSP
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCH
WQGCVSWISPLAWHPTNQNAVIMVDLTRDPTPLIELSSEEIRERLYTRKDELGDLAAIPV
HHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCCEEECCE
KLVHINKCRVLAPAATLTPERADELTIDREQCRKSLNLLRAHPEVREKLVEVFNQEFEGS
EEEEECCCEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
NDPDPDTQLYAGFFGHGDKSTMDLVRATPADLLGEREFAFTDARLPEMLFRYRARNWPHT
CCCCCCHHEEEHHHCCCCCHHHHHHHCCCHHHHCCCCCEECHHHHHHHHHHHHHCCCCCH
LSEAEQKRWRLHCSDYFSRRLPDYAPRLEALAEQNQGNERNFAILKSLYRYLEDL
HHHHHHHHHEECHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]