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The map label for this gene is galE [H]

Identifier: 145299343

GI number: 145299343

Start: 2549026

End: 2550048

Strand: Direct

Name: galE [H]

Synonym: ASA_2390

Alternate gene names: 145299343

Gene position: 2549026-2550048 (Clockwise)

Preceding gene: 145299339

Following gene: 145299344

Centisome position: 54.21

GC content: 57.28

Gene sequence:

>1023_bases
ATGTTGAAAATCCTTGTCACCGGTGGAACTGGTTACATAGGAAGTCATACCTGTCTGCAGCTTATCGCTGCCGGTATGAC
CCCCATACTGTTAGATAACCTCGCCAACAGCAAAGAAAGTGTTCTCGAACGTATCCAAACTCTCAGTGGGCAGCGCCCAG
TGCTCTATCGGGGGGATGTGCGTGACGCCAGCTTGCTGGATCGGGTGTTCGCGGAACAGCAGATTGATGCCGTGATCCAT
TTCGCCGGACTCAAGGCCGTCGGGGAATCAGTGCAAAAACCCCTTGAATACTATGACAATAATGTCAGCGGCACTCTGGT
TTTGTTGCAGGCGATGCAGCGTGCCGGGGTCAAGACGTTGCTGTTCAGCTCATCGGCCACCGTCTACGGCGAGCCGGACA
CCATGCCTGTCCGAGAGGAGAGCCCAACCCTGCAAGCCACCAATCCTTATGGCCAGAGCAAGCTGATGGTTGAGCGCCTC
ATCAAGGACTTTGCCAATGCGGCGCCCGATTGGTCATTGACCCTGCTGCGCTATTTCAATCCGGTGGGCGCTCATCCCAG
TGGCTTGATGGGTGAGGACCCACAGGGGATCCCCAACAATCTGATGCCCTATATTGCCCAGGTGGCGGTAGGACGCCGTG
ACAAACTCGCCATTTTTGGGGATGACTATCCCACCCCGGATAGCACTGGCGTGCGCGATTACATTCATGTGATGGATCTG
GCCGACGGGCATGTGGCGGCCTTGCAGAGCAAGCTCGGGCAGTCGGGCGTTCATGTCTACAACCTGGGAACAGGACATGG
CTACAGCGTTCTCGACATACACGCCGCCTTCTCCCGGGCCTGTGGCCGTGACCTGCCTTATGAAATAGTGCCACGGCGCA
CGGGGGATATCGCCCAATGCTGGGCAGATCCCAGCCGGGCCCTCACCGAGCTGGGCTGGCAAGCTCATCGCACCATTGAT
GACATGACCGCCGATACCTGGCGCTGGCAATCACAAAATCCGAACGGCTATCCAACCCTATGA

Upstream 100 bases:

>100_bases
ATGCACAGCCATCTTCCCTCCCCTTTCCGGCAAGAGCACAATAAGGGAAAGCGGTTACACGATAAAAACACCAACAGGAA
TGAGCACCAAGGAGCACCAC

Downstream 100 bases:

>100_bases
GTGGCCAGCACGAGGAGCAATTATCCATGCAATTTGAACCAACCGATCACCCGCATCGTCGTTATAACCCGCTGATCCAG
CAGTGGGTACTCGTCTCGCC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLKILVTGGTGYIGSHTCLQLIAAGMTPILLDNLANSKESVLERIQTLSGQRPVLYRGDVRDASLLDRVFAEQQIDAVIH
FAGLKAVGESVQKPLEYYDNNVSGTLVLLQAMQRAGVKTLLFSSSATVYGEPDTMPVREESPTLQATNPYGQSKLMVERL
IKDFANAAPDWSLTLLRYFNPVGAHPSGLMGEDPQGIPNNLMPYIAQVAVGRRDKLAIFGDDYPTPDSTGVRDYIHVMDL
ADGHVAALQSKLGQSGVHVYNLGTGHGYSVLDIHAAFSRACGRDLPYEIVPRRTGDIAQCWADPSRALTELGWQAHRTID
DMTADTWRWQSQNPNGYPTL

Sequences:

>Translated_340_residues
MLKILVTGGTGYIGSHTCLQLIAAGMTPILLDNLANSKESVLERIQTLSGQRPVLYRGDVRDASLLDRVFAEQQIDAVIH
FAGLKAVGESVQKPLEYYDNNVSGTLVLLQAMQRAGVKTLLFSSSATVYGEPDTMPVREESPTLQATNPYGQSKLMVERL
IKDFANAAPDWSLTLLRYFNPVGAHPSGLMGEDPQGIPNNLMPYIAQVAVGRRDKLAIFGDDYPTPDSTGVRDYIHVMDL
ADGHVAALQSKLGQSGVHVYNLGTGHGYSVLDIHAAFSRACGRDLPYEIVPRRTGDIAQCWADPSRALTELGWQAHRTID
DMTADTWRWQSQNPNGYPTL
>Mature_340_residues
MLKILVTGGTGYIGSHTCLQLIAAGMTPILLDNLANSKESVLERIQTLSGQRPVLYRGDVRDASLLDRVFAEQQIDAVIH
FAGLKAVGESVQKPLEYYDNNVSGTLVLLQAMQRAGVKTLLFSSSATVYGEPDTMPVREESPTLQATNPYGQSKLMVERL
IKDFANAAPDWSLTLLRYFNPVGAHPSGLMGEDPQGIPNNLMPYIAQVAVGRRDKLAIFGDDYPTPDSTGVRDYIHVMDL
ADGHVAALQSKLGQSGVHVYNLGTGHGYSVLDIHAAFSRACGRDLPYEIVPRRTGDIAQCWADPSRALTELGWQAHRTID
DMTADTWRWQSQNPNGYPTL

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=55.6851311953353, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=55.6851311953353, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=55.6851311953353, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=28.4671532846715, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=63.2047477744807, Blast_Score=453, Evalue=1e-129,
Organism=Escherichia coli, GI1788353, Length=368, Percent_Identity=26.6304347826087, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994969, Length=361, Percent_Identity=23.2686980609418, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=50.1449275362319, Blast_Score=359, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=49.8559077809798, Blast_Score=358, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=26.5243902439024, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=51.3119533527697, Blast_Score=363, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=54.9707602339181, Blast_Score=396, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37212; Mature: 37212

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKILVTGGTGYIGSHTCLQLIAAGMTPILLDNLANSKESVLERIQTLSGQRPVLYRGDV
CEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCC
RDASLLDRVFAEQQIDAVIHFAGLKAVGESVQKPLEYYDNNVSGTLVLLQAMQRAGVKTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
LFSSSATVYGEPDTMPVREESPTLQATNPYGQSKLMVERLIKDFANAAPDWSLTLLRYFN
EEECCCEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PVGAHPSGLMGEDPQGIPNNLMPYIAQVAVGRRDKLAIFGDDYPTPDSTGVRDYIHVMDL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHC
ADGHVAALQSKLGQSGVHVYNLGTGHGYSVLDIHAAFSRACGRDLPYEIVPRRTGDIAQC
CCCHHHHHHHHHCCCCCEEEECCCCCCCEEEHHHHHHHHHHCCCCCCEECCCCCCCHHHH
WADPSRALTELGWQAHRTIDDMTADTWRWQSQNPNGYPTL
HCCHHHHHHHHCHHHHHHHHHCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MLKILVTGGTGYIGSHTCLQLIAAGMTPILLDNLANSKESVLERIQTLSGQRPVLYRGDV
CEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCC
RDASLLDRVFAEQQIDAVIHFAGLKAVGESVQKPLEYYDNNVSGTLVLLQAMQRAGVKTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
LFSSSATVYGEPDTMPVREESPTLQATNPYGQSKLMVERLIKDFANAAPDWSLTLLRYFN
EEECCCEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PVGAHPSGLMGEDPQGIPNNLMPYIAQVAVGRRDKLAIFGDDYPTPDSTGVRDYIHVMDL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHC
ADGHVAALQSKLGQSGVHVYNLGTGHGYSVLDIHAAFSRACGRDLPYEIVPRRTGDIAQC
CCCHHHHHHHHHCCCCCEEEECCCCCCCEEEHHHHHHHHHHCCCCCCEECCCCCCCHHHH
WADPSRALTELGWQAHRTIDDMTADTWRWQSQNPNGYPTL
HCCHHHHHHHHCHHHHHHHHHCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]