| Definition | Aeromonas salmonicida subsp. salmonicida A449, complete genome. |
|---|---|
| Accession | NC_009348 |
| Length | 4,702,402 |
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The map label for this gene is fabG [C]
Identifier: 145299171
GI number: 145299171
Start: 2333727
End: 2334458
Strand: Direct
Name: fabG [C]
Synonym: ASA_2202
Alternate gene names: 145299171
Gene position: 2333727-2334458 (Clockwise)
Preceding gene: 145299167
Following gene: 145299173
Centisome position: 49.63
GC content: 63.93
Gene sequence:
>732_bases ATGACCCGTTCCATCGCCCTCATCACAGGCGCCAGCCGCGGCCTAGGCAAACACTCGGCCCTGGCCCTCGCCGCCAAAGG CGTCGATCTCATCATCACCTATCACAGCCAGGCCGAAGAGGCGGCTGCCGTGGTGGCGCAGGCCAATGCGCTCGATGTGG CCGACAGCGCCTCCTTTGCCGCCTTCGCGGCTGAGGTGCACCAATTGCTGCAGCGAGAGTGGCAACGGGAGCGGTTCGAC TTTCTGGTCAACAATGCCGGCATCGGCATCCACACCAGCTTCGAGCAGACCACAGAGCAGCAGTTCGATACCCTCATGAA CATTCACCTCAAGGGGACCTTCTTCCTGACCCAGCAGCTGTTGCCCCTGATCCGCGATGGCGGGCGCATCATCAACCTCT CGACCGGTCTCACCCGTTTCGCGCTGCCCGGTTATGCCGCCTACGCAGCCATGAAGGGGGGAATAGAGGTGTTGACCCGC TATCTGGCCAAGGAGCTGGGCCCGCGCGGGATCGCCGTCAACGTGGTGGCACCCGGTGCTATCGAGACTGATTTTGGCGG GGGTGTGGTGCGGGACAACCAGGCGGTCAACGACTTCATCGCCAGCCAGACCGCGCTCGGGCGAGTCGGCCAGCCCGACG ACATAGGCGGCCTGATAGCGGCCCTGCTCTCGGATGACAATCGCTGGGTCAATGCCCAGCGCATCGAGGCCTCGGGGGGC ATGTTCATCTAG
Upstream 100 bases:
>100_bases CATCTATTATTACCCTCTTTATCCATAATGTACGTACCAATAGAGTGGCACTACCGGCTCGTCTCGAGCCCGCACCCACC CCATTGACAGGAGTCGTACC
Downstream 100 bases:
>100_bases CGCCCCCCATCACTGGATAGGAAAATGGCCATGCAAAAGGCCCTGCCGTGAGGCAGGGCCTTTTCGTATGACAAGGCCAG GGGATGCGTTAAAGCGCCTT
Product: short-chain dehydrogenase/reductase family protein
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: ORFC [H]
Number of amino acids: Translated: 243; Mature: 242
Protein sequence:
>243_residues MTRSIALITGASRGLGKHSALALAAKGVDLIITYHSQAEEAAAVVAQANALDVADSASFAAFAAEVHQLLQREWQRERFD FLVNNAGIGIHTSFEQTTEQQFDTLMNIHLKGTFFLTQQLLPLIRDGGRIINLSTGLTRFALPGYAAYAAMKGGIEVLTR YLAKELGPRGIAVNVVAPGAIETDFGGGVVRDNQAVNDFIASQTALGRVGQPDDIGGLIAALLSDDNRWVNAQRIEASGG MFI
Sequences:
>Translated_243_residues MTRSIALITGASRGLGKHSALALAAKGVDLIITYHSQAEEAAAVVAQANALDVADSASFAAFAAEVHQLLQREWQRERFD FLVNNAGIGIHTSFEQTTEQQFDTLMNIHLKGTFFLTQQLLPLIRDGGRIINLSTGLTRFALPGYAAYAAMKGGIEVLTR YLAKELGPRGIAVNVVAPGAIETDFGGGVVRDNQAVNDFIASQTALGRVGQPDDIGGLIAALLSDDNRWVNAQRIEASGG MFI >Mature_242_residues TRSIALITGASRGLGKHSALALAAKGVDLIITYHSQAEEAAAVVAQANALDVADSASFAAFAAEVHQLLQREWQRERFDF LVNNAGIGIHTSFEQTTEQQFDTLMNIHLKGTFFLTQQLLPLIRDGGRIINLSTGLTRFALPGYAAYAAMKGGIEVLTRY LAKELGPRGIAVNVVAPGAIETDFGGGVVRDNQAVNDFIASQTALGRVGQPDDIGGLIAALLSDDNRWVNAQRIEASGGM FI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=29.6442687747036, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=30.0411522633745, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=26.530612244898, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=25.9259259259259, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=24.7058823529412, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=31.8918918918919, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI150247226, Length=186, Percent_Identity=32.7956989247312, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=156, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI44680136, Length=99, Percent_Identity=39.3939393939394, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI44680133, Length=99, Percent_Identity=39.3939393939394, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI17738292, Length=99, Percent_Identity=39.3939393939394, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=27.3913043478261, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI20149619, Length=221, Percent_Identity=28.9592760180996, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI223718074, Length=215, Percent_Identity=30.2325581395349, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI22507405, Length=195, Percent_Identity=27.1794871794872, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=24, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=31.25, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.0739299610895, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=31.0483870967742, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367365, Length=233, Percent_Identity=30.0429184549356, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.6451612903226, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=29.9595141700405, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=28.5123966942149, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=30.0411522633745, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=26.6932270916335, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786701, Length=214, Percent_Identity=29.9065420560748, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=28.7449392712551, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=28.3400809716599, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.8804780876494, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=31.0756972111554, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17559104, Length=246, Percent_Identity=31.3008130081301, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=28.9795918367347, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.9433962264151, Blast_Score=84, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17561272, Length=231, Percent_Identity=28.1385281385281, Blast_Score=84, Evalue=4e-17, Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=27.9166666666667, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17562904, Length=253, Percent_Identity=29.6442687747036, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=29.0076335877863, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.8507462686567, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=30.3846153846154, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=27.1255060728745, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71982365, Length=195, Percent_Identity=32.8205128205128, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=29.3893129770992, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=30.078125, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=28.957528957529, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.9245283018868, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=25.2, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=29.277566539924, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17536651, Length=168, Percent_Identity=31.547619047619, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=29.4573643410853, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17558628, Length=191, Percent_Identity=29.8429319371728, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=27.7992277992278, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=32.8042328042328, Blast_Score=85, Evalue=8e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=240, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=220, Percent_Identity=26.8181818181818, Blast_Score=63, Evalue=3e-11, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.3886639676113, Blast_Score=112, Evalue=1e-25, Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=33.6065573770492, Blast_Score=107, Evalue=6e-24, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=33.201581027668, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=35.2, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.1632653061224, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24644337, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24651139, Length=198, Percent_Identity=29.7979797979798, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=31.7460317460317, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI161076933, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24584744, Length=223, Percent_Identity=25.1121076233184, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI28574402, Length=223, Percent_Identity=25.1121076233184, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=28.0612244897959, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 25896; Mature: 25765
Theoretical pI: Translated: 5.62; Mature: 5.62
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTRSIALITGASRGLGKHSALALAAKGVDLIITYHSQAEEAAAVVAQANALDVADSASFA CCCEEEEEECCCCCCCCHHHHEEEECCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHH AFAAEVHQLLQREWQRERFDFLVNNAGIGIHTSFEQTTEQQFDTLMNIHLKGTFFLTQQL HHHHHHHHHHHHHHHHHHHHHEECCCCCEEECCHHHHHHHHHHHHHHEEECCHHHHHHHH LPLIRDGGRIINLSTGLTRFALPGYAAYAAMKGGIEVLTRYLAKELGPRGIAVNVVAPGA HHHHHCCCEEEEECCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCC IETDFGGGVVRDNQAVNDFIASQTALGRVGQPDDIGGLIAALLSDDNRWVNAQRIEASGG EEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECEEEEECCCC MFI CCC >Mature Secondary Structure TRSIALITGASRGLGKHSALALAAKGVDLIITYHSQAEEAAAVVAQANALDVADSASFA CCEEEEEECCCCCCCCHHHHEEEECCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHH AFAAEVHQLLQREWQRERFDFLVNNAGIGIHTSFEQTTEQQFDTLMNIHLKGTFFLTQQL HHHHHHHHHHHHHHHHHHHHHEECCCCCEEECCHHHHHHHHHHHHHHEEECCHHHHHHHH LPLIRDGGRIINLSTGLTRFALPGYAAYAAMKGGIEVLTRYLAKELGPRGIAVNVVAPGA HHHHHCCCEEEEECCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCC IETDFGGGVVRDNQAVNDFIASQTALGRVGQPDDIGGLIAALLSDDNRWVNAQRIEASGG EEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECEEEEECCCC MFI CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8868443 [H]