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The map label for this gene is namA [H]

Identifier: 145297030

GI number: 145297030

Start: 3248793

End: 3249905

Strand: Reverse

Name: namA [H]

Synonym: cgR_2927

Alternate gene names: 145297030

Gene position: 3249905-3248793 (Counterclockwise)

Preceding gene: 145297033

Following gene: 145297026

Centisome position: 98.06

GC content: 53.64

Gene sequence:

>1113_bases
GTGGATTTTTGGACTATTCTCGACACCATGACTTCCCTCCTTACTCCCATTGCAATCCGTGGATTAGAAATTCCCAATAG
GATGTGGCTCGCGCCCATGTGCCAGTACCAAGCCAATAACCTCGATGGGGTTCCACTTGATTGGCACCTCGTGCATTACG
GAGCCCGAGCTGTTGGCGGCTTCGGACTACTCATCGCGGAATCCACCGGCATTAGTCCAGAGGGAAGAATCTCATCGCGT
TGCACTGGCCTATGGAATGAGGCCCAAGTTGAGGCATGGGAGAGAATTACAAATTTTGTCCACGCTCAAGGTGGACTGAT
CGGTGTGCAACTTAACCATGCAGGCCGCAAAGCGAGCACATATCCGGCCCTTCCTAACTTCTCTACTGGTACTCAATCAG
TTGACGAGGGTGGATGGGAAACCTTTGGGCCTAGTGCTGTCGCTCAGCCGGGGCTTGCAGATCCGACCGAATTGACCCGC
GAAGGTATTGAAAAGGTTATTCAGAATTTCGCAGCTGCTGCAGAGCGTGCGGTGCGTGCAGGGTTTGATGCTGTGGAGGT
CCATGGTGCCCACGGTTACCTGTTGCATCAGTTCCTCACTCCCCTCGCAAATAAACGGACAGATATTTATGGTGGTTCGT
TTGAGAATCGCACTCGACTATTTAGGGAAGTTGCCCAGGCGATCCGTGCAGTGATTCCTGACTCGATGCCACTGATTGCC
CGGATCTCTGCCACGGACTGGATTGATGATGAACCTTCGTGGGATGACGATCAAACCGTCTCGCTTGTGTCAGATCTGAA
GAAGCTGGGTGTGGATGCAGTCGATATTTCCACCGGAGGTGCAGTACCCGCGACAATCCCTGTGGAGCCGAGCTATCAAG
TGAAATTTGCTCGTCGTGTGAAGCAAGAGGTGGGTATCCCTACCTCCGCGGTTGGATTAATTACTCATGTGGGTCAGGCG
CAGGGGCATCTTGATCGTGGAGATGCGGACATTATTTCGCTGGGTCGAGCTGCCCTCCGCTACCCTTCCTGGCCACTATT
TGCTGCGCATGAACTGGGGAGAACTCGCGATGAGATCCCCTACCCACCTTCCTATGTGCGAGGTGCGTGGTAG

Upstream 100 bases:

>100_bases
AAATAGTGGGATTAACCCATTAATTTTATCGCTCAATTTAGTTTCGTCACTGTGTCGTTAATCAATTGACTTCCTGTGTG
GATGAATCAGCGCAAGGATT

Downstream 100 bases:

>100_bases
AAAAATGGCGATGTTTCACGTGAAACATCGCCATTTTTTGTCTGTTTTTCTACTGCACGGACGCGCTCAGAGTGTCGCCG
TCCTGCTTGAGATTGGCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDFWTILDTMTSLLTPIAIRGLEIPNRMWLAPMCQYQANNLDGVPLDWHLVHYGARAVGGFGLLIAESTGISPEGRISSR
CTGLWNEAQVEAWERITNFVHAQGGLIGVQLNHAGRKASTYPALPNFSTGTQSVDEGGWETFGPSAVAQPGLADPTELTR
EGIEKVIQNFAAAAERAVRAGFDAVEVHGAHGYLLHQFLTPLANKRTDIYGGSFENRTRLFREVAQAIRAVIPDSMPLIA
RISATDWIDDEPSWDDDQTVSLVSDLKKLGVDAVDISTGGAVPATIPVEPSYQVKFARRVKQEVGIPTSAVGLITHVGQA
QGHLDRGDADIISLGRAALRYPSWPLFAAHELGRTRDEIPYPPSYVRGAW

Sequences:

>Translated_370_residues
MDFWTILDTMTSLLTPIAIRGLEIPNRMWLAPMCQYQANNLDGVPLDWHLVHYGARAVGGFGLLIAESTGISPEGRISSR
CTGLWNEAQVEAWERITNFVHAQGGLIGVQLNHAGRKASTYPALPNFSTGTQSVDEGGWETFGPSAVAQPGLADPTELTR
EGIEKVIQNFAAAAERAVRAGFDAVEVHGAHGYLLHQFLTPLANKRTDIYGGSFENRTRLFREVAQAIRAVIPDSMPLIA
RISATDWIDDEPSWDDDQTVSLVSDLKKLGVDAVDISTGGAVPATIPVEPSYQVKFARRVKQEVGIPTSAVGLITHVGQA
QGHLDRGDADIISLGRAALRYPSWPLFAAHELGRTRDEIPYPPSYVRGAW
>Mature_370_residues
MDFWTILDTMTSLLTPIAIRGLEIPNRMWLAPMCQYQANNLDGVPLDWHLVHYGARAVGGFGLLIAESTGISPEGRISSR
CTGLWNEAQVEAWERITNFVHAQGGLIGVQLNHAGRKASTYPALPNFSTGTQSVDEGGWETFGPSAVAQPGLADPTELTR
EGIEKVIQNFAAAAERAVRAGFDAVEVHGAHGYLLHQFLTPLANKRTDIYGGSFENRTRLFREVAQAIRAVIPDSMPLIA
RISATDWIDDEPSWDDDQTVSLVSDLKKLGVDAVDISTGGAVPATIPVEPSYQVKFARRVKQEVGIPTSAVGLITHVGQA
QGHLDRGDADIISLGRAALRYPSWPLFAAHELGRTRDEIPYPPSYVRGAW

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=337, Percent_Identity=31.7507418397626, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789463, Length=355, Percent_Identity=30.1408450704225, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17565138, Length=245, Percent_Identity=32.2448979591837, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17564188, Length=273, Percent_Identity=29.3040293040293, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=273, Percent_Identity=30.03663003663, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI72001454, Length=275, Percent_Identity=29.8181818181818, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=247, Percent_Identity=33.1983805668016, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17566914, Length=286, Percent_Identity=29.020979020979, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=348, Percent_Identity=27.2988505747126, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325086, Length=227, Percent_Identity=32.15859030837, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321973, Length=231, Percent_Identity=32.034632034632, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40272; Mature: 40272

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFWTILDTMTSLLTPIAIRGLEIPNRMWLAPMCQYQANNLDGVPLDWHLVHYGARAVGG
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
FGLLIAESTGISPEGRISSRCTGLWNEAQVEAWERITNFVHAQGGLIGVQLNHAGRKAST
EEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
YPALPNFSTGTQSVDEGGWETFGPSAVAQPGLADPTELTREGIEKVIQNFAAAAERAVRA
CCCCCCCCCCCCCHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GFDAVEVHGAHGYLLHQFLTPLANKRTDIYGGSFENRTRLFREVAQAIRAVIPDSMPLIA
CCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
RISATDWIDDEPSWDDDQTVSLVSDLKKLGVDAVDISTGGAVPATIPVEPSYQVKFARRV
EECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCHHHHHHHHH
KQEVGIPTSAVGLITHVGQAQGHLDRGDADIISLGRAALRYPSWPLFAAHELGRTRDEIP
HHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
YPPSYVRGAW
CCCCCCCCCC
>Mature Secondary Structure
MDFWTILDTMTSLLTPIAIRGLEIPNRMWLAPMCQYQANNLDGVPLDWHLVHYGARAVGG
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
FGLLIAESTGISPEGRISSRCTGLWNEAQVEAWERITNFVHAQGGLIGVQLNHAGRKAST
EEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
YPALPNFSTGTQSVDEGGWETFGPSAVAQPGLADPTELTREGIEKVIQNFAAAAERAVRA
CCCCCCCCCCCCCHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GFDAVEVHGAHGYLLHQFLTPLANKRTDIYGGSFENRTRLFREVAQAIRAVIPDSMPLIA
CCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
RISATDWIDDEPSWDDDQTVSLVSDLKKLGVDAVDISTGGAVPATIPVEPSYQVKFARRV
EECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCHHHHHHHHH
KQEVGIPTSAVGLITHVGQAQGHLDRGDADIISLGRAALRYPSWPLFAAHELGRTRDEIP
HHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
YPPSYVRGAW
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA