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The map label for this gene is ulaC [H]

Identifier: 145297026

GI number: 145297026

Start: 3244850

End: 3245662

Strand: Reverse

Name: ulaC [H]

Synonym: cgR_2923

Alternate gene names: 145297026

Gene position: 3245662-3244850 (Counterclockwise)

Preceding gene: 145297030

Following gene: 145297025

Centisome position: 97.93

GC content: 54.98

Gene sequence:

>813_bases
ATGTTTGTACTCAAAGATCTGCTCAAGGCAGAACGCATAGAACTCGACCGCACGGTCACCGATTGGCGTGAAGGCATCCG
CGCCGCAGGTGTACTCCTAGAAAAGACAAACAGCATTGATTCCGCCTACACCGATGCCATGATCGCCAGCGTGGAAGAAA
AAGGCCCCTACATTGTGGTCGCTCCAGGTTTCGCTTTCGCACACGCCCGCCCCAGCAGAGCAGTCCACGAGACCGCTATG
TCGTGGGTGCGCCTGGCCTCCCCTGTTTCCTTCGGTCACAGTAAGAATGATCCCGTCAATCTCATCGTTGCTCTCGCTGC
CAAAGATGCCACCGCACATACCCAAGCGATGGCGGCATTGGCTAAAGCTTTAGGAAAATACCGAAAGGATCTCGACGAGG
CACAAAGTCCCGAGGAGATCCAAGCAATCTTAGAGAAGGCAGCAGCGCCAGCGAAGCAGAAGGCTCCTGCTGTGGCGCCT
GCTGTAACACCCACTGACGCTCCTGCAGCCTCAGTCCAATCCAAAAGCCACGACAAGATCCTCACCGTCTGTGGCAACGG
CTTGGGTACCTCCCTCTTCCTCAAAAACACCCTTGAGCAAGTTTTCGACACCTGGGGTTGGGGTCCATACATGACGGTGG
AGGCAACCGACACTATCTCCGCTAAGGGCAAAGCCAAGGAAGCTGATCTCATCATGACCTCTGGTGAAATCGCCCGCACG
TTGGGTGATGTTGGAATCCCGGTTCACGTGATCAATGACTTCACGAGCACCGATGAAATCGATGCTGCGCTTCGTGAACG
CTACGACATCTAA

Upstream 100 bases:

>100_bases
GGAACTTCGAGGTGCCTTCGTGGGGCGTACGGAGATCTAGCAAGTGTGGCTTTATGTTTGACCCTATCCGAATCAACATG
CAGTGAATTAACATCTACTT

Downstream 100 bases:

>100_bases
CTACTTTAAAAGGACGAAAATATTATGGACTGGTTAACCATTCCTCTTTTCCTCGTTAATGAAATCCTTGCGGTTCCGGC
TTTCCTCATCGGTATCATCA

Product: hypothetical protein

Products: Protein Histidine; Sugar Phosphate. [C]

Alternate protein names: PTS system ascorbate-specific EIIA component [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MFVLKDLLKAERIELDRTVTDWREGIRAAGVLLEKTNSIDSAYTDAMIASVEEKGPYIVVAPGFAFAHARPSRAVHETAM
SWVRLASPVSFGHSKNDPVNLIVALAAKDATAHTQAMAALAKALGKYRKDLDEAQSPEEIQAILEKAAAPAKQKAPAVAP
AVTPTDAPAASVQSKSHDKILTVCGNGLGTSLFLKNTLEQVFDTWGWGPYMTVEATDTISAKGKAKEADLIMTSGEIART
LGDVGIPVHVINDFTSTDEIDAALRERYDI

Sequences:

>Translated_270_residues
MFVLKDLLKAERIELDRTVTDWREGIRAAGVLLEKTNSIDSAYTDAMIASVEEKGPYIVVAPGFAFAHARPSRAVHETAM
SWVRLASPVSFGHSKNDPVNLIVALAAKDATAHTQAMAALAKALGKYRKDLDEAQSPEEIQAILEKAAAPAKQKAPAVAP
AVTPTDAPAASVQSKSHDKILTVCGNGLGTSLFLKNTLEQVFDTWGWGPYMTVEATDTISAKGKAKEADLIMTSGEIART
LGDVGIPVHVINDFTSTDEIDAALRERYDI
>Mature_270_residues
MFVLKDLLKAERIELDRTVTDWREGIRAAGVLLEKTNSIDSAYTDAMIASVEEKGPYIVVAPGFAFAHARPSRAVHETAM
SWVRLASPVSFGHSKNDPVNLIVALAAKDATAHTQAMAALAKALGKYRKDLDEAQSPEEIQAILEKAAAPAKQKAPAVAP
AVTPTDAPAASVQSKSHDKILTVCGNGLGTSLFLKNTLEQVFDTWGWGPYMTVEATDTISAKGKAKEADLIMTSGEIART
LGDVGIPVHVINDFTSTDEIDAALRERYDI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=143, Percent_Identity=31.4685314685315, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790755, Length=101, Percent_Identity=34.6534653465347, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789302, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 28942; Mature: 28942

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLKDLLKAERIELDRTVTDWREGIRAAGVLLEKTNSIDSAYTDAMIASVEEKGPYIVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEE
APGFAFAHARPSRAVHETAMSWVRLASPVSFGHSKNDPVNLIVALAAKDATAHTQAMAAL
ECCCHHHCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHH
AKALGKYRKDLDEAQSPEEIQAILEKAAAPAKQKAPAVAPAVTPTDAPAASVQSKSHDKI
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHCCCCCCCE
LTVCGNGLGTSLFLKNTLEQVFDTWGWGPYMTVEATDTISAKGKAKEADLIMTSGEIART
EEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECHHHHHH
LGDVGIPVHVINDFTSTDEIDAALRERYDI
HHCCCCCEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFVLKDLLKAERIELDRTVTDWREGIRAAGVLLEKTNSIDSAYTDAMIASVEEKGPYIVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEE
APGFAFAHARPSRAVHETAMSWVRLASPVSFGHSKNDPVNLIVALAAKDATAHTQAMAAL
ECCCHHHCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHH
AKALGKYRKDLDEAQSPEEIQAILEKAAAPAKQKAPAVAPAVTPTDAPAASVQSKSHDKI
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHCCCCCCCE
LTVCGNGLGTSLFLKNTLEQVFDTWGWGPYMTVEATDTISAKGKAKEADLIMTSGEIART
EEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECHHHHHH
LGDVGIPVHVINDFTSTDEIDAALRERYDI
HHCCCCCEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-Phosphohistidine; Sugar [C]

Specific reaction: Protein N-Phosphohistidine + Sugar = Protein Histidine + Sugar Phosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]