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The map label for this gene is macB [H]

Identifier: 145296983

GI number: 145296983

Start: 3196515

End: 3197780

Strand: Reverse

Name: macB [H]

Synonym: cgR_2882

Alternate gene names: 145296983

Gene position: 3197780-3196515 (Counterclockwise)

Preceding gene: 145296984

Following gene: 145296982

Centisome position: 96.49

GC content: 52.21

Gene sequence:

>1266_bases
ATGAGCCTTGCAGAATCAATTCTTTTGGCGCTCACCAGCCTGAGAAGCAACAAGATGCGTGCATTGTTGACGCTGTTGGG
TGTCATCATTGGTATCGCATCAGTCATCGGAATTTTGACCATTGGTAAAGCCCTGCAGGATCAAACTTTGAATAGTTTGG
AAAGCTTGGGCGCGAATGATCTGTCGGCGCAGGTGGAGGAACGCCCCGACGAAGATTCCCCCGAACCCGATATGTTCGCT
TTTTCTGGGGCTGCAAACTCTAGTGGCAATCTGATTCCAGAAGAAACAGTTGATACGCTGCGCGATCGTTTCGCGGGCAG
CATCACGGGAATCAGCGTTGGCGGAATGGGTACGCAAGGCACTCTCATCGGCGACACCGCAGATCTTAAATCCGATCTCC
TCGGCGTCAACGAGGATTATATGTGGATGAATGGCGTCGAAATGAACTACGGCCGCGCCATCACGCAAGACGATGTTGCC
GCTCAGCGCCCCGTTGCAGTCATCGCCCCAGACACCTTTAATACGCTTTTCGACGCAAACCCCAACCTCGCTCTGGGGTC
CGAAGTAGCTTTTGAACTCAACGGTCAAGAGACATTTTTGCGGGTTATCGGCGTGTATAAAGAAGCCGCAGCAGGTGGAC
TTGTGGGAAGCATGCCAACCGTCAACACCTACACCCCATATACGGTGGCCAATGACATCACCCACACGGAAGATGGATTC
AACACGTTAAGTATCCGTGCAGCTCAGGGCGTAGACCAGGATTCACTTAAGGGTTCACTGCAGACCTACTTCGACGCGCT
GTACGCCAACAATGACTCGCACCACGTTGCCATGTTGGACTTCCGTAAACAGATCGAAGAGTTCAACACCATTCTCGGCG
CAATGAGTTTGGGTATCTCAGCCATCGGCGGAATTTCCTTGCTTGTCGGTGGCATCGGAGTGATGAACATTATGTTGGTG
TCTGTCACCGAGCGAACCCGCGAAATCGGTGTTCGAAAAGCCCTCGGCGCTCGTCGACGTGACATTCGCCTGCAATTCGT
CGTTGAAGCCATGATCATTTGTTTCATCGGTGGCATCCTCGGCGTGCTTTTGGGTGGCATTTTGGGATTGATCATGTCCA
GCGCTATTGGCTACATTTCCTTGCCACCACTGAGTGGAATCGTGATCGCCTTGGTATTTTCCATGGCTATCGGCCTGTTT
TTCGGCTACTACCCCGCCAACAAGGCAGCAAAGCTCGATCCAATTGACGCCTTGCGTTATGAGTAA

Upstream 100 bases:

>100_bases
CCATCGTGTTTATTACTCACAACCCTGAGCTTGCTGATGAATCTGATCGGGTGGTCACCATGGTTGACGGGCGCATCATT
GGGTCTGAGGTGAAACACTC

Downstream 100 bases:

>100_bases
AAGCCTCGTTTTTAAGGTAGCCACACATCGCACTAGACTGAAGAACTGTGGCTACCTCAAAAATTCTTCTTTATTACGCA
TTCACCCCGCTCTCTGACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSLAESILLALTSLRSNKMRALLTLLGVIIGIASVIGILTIGKALQDQTLNSLESLGANDLSAQVEERPDEDSPEPDMFA
FSGAANSSGNLIPEETVDTLRDRFAGSITGISVGGMGTQGTLIGDTADLKSDLLGVNEDYMWMNGVEMNYGRAITQDDVA
AQRPVAVIAPDTFNTLFDANPNLALGSEVAFELNGQETFLRVIGVYKEAAAGGLVGSMPTVNTYTPYTVANDITHTEDGF
NTLSIRAAQGVDQDSLKGSLQTYFDALYANNDSHHVAMLDFRKQIEEFNTILGAMSLGISAIGGISLLVGGIGVMNIMLV
SVTERTREIGVRKALGARRRDIRLQFVVEAMIICFIGGILGVLLGGILGLIMSSAIGYISLPPLSGIVIALVFSMAIGLF
FGYYPANKAAKLDPIDALRYE

Sequences:

>Translated_421_residues
MSLAESILLALTSLRSNKMRALLTLLGVIIGIASVIGILTIGKALQDQTLNSLESLGANDLSAQVEERPDEDSPEPDMFA
FSGAANSSGNLIPEETVDTLRDRFAGSITGISVGGMGTQGTLIGDTADLKSDLLGVNEDYMWMNGVEMNYGRAITQDDVA
AQRPVAVIAPDTFNTLFDANPNLALGSEVAFELNGQETFLRVIGVYKEAAAGGLVGSMPTVNTYTPYTVANDITHTEDGF
NTLSIRAAQGVDQDSLKGSLQTYFDALYANNDSHHVAMLDFRKQIEEFNTILGAMSLGISAIGGISLLVGGIGVMNIMLV
SVTERTREIGVRKALGARRRDIRLQFVVEAMIICFIGGILGVLLGGILGLIMSSAIGYISLPPLSGIVIALVFSMAIGLF
FGYYPANKAAKLDPIDALRYE
>Mature_420_residues
SLAESILLALTSLRSNKMRALLTLLGVIIGIASVIGILTIGKALQDQTLNSLESLGANDLSAQVEERPDEDSPEPDMFAF
SGAANSSGNLIPEETVDTLRDRFAGSITGISVGGMGTQGTLIGDTADLKSDLLGVNEDYMWMNGVEMNYGRAITQDDVAA
QRPVAVIAPDTFNTLFDANPNLALGSEVAFELNGQETFLRVIGVYKEAAAGGLVGSMPTVNTYTPYTVANDITHTEDGFN
TLSIRAAQGVDQDSLKGSLQTYFDALYANNDSHHVAMLDFRKQIEEFNTILGAMSLGISAIGGISLLVGGIGVMNIMLVS
VTERTREIGVRKALGARRRDIRLQFVVEAMIICFIGGILGVLLGGILGLIMSSAIGYISLPPLSGIVIALVFSMAIGLFF
GYYPANKAAKLDPIDALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=419, Percent_Identity=31.2649164677804, Blast_Score=169, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44715; Mature: 44584

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAESILLALTSLRSNKMRALLTLLGVIIGIASVIGILTIGKALQDQTLNSLESLGAND
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSAQVEERPDEDSPEPDMFAFSGAANSSGNLIPEETVDTLRDRFAGSITGISVGGMGTQG
HHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCC
TLIGDTADLKSDLLGVNEDYMWMNGVEMNYGRAITQDDVAAQRPVAVIAPDTFNTLFDAN
CEECCHHHHHHHHCCCCCCCEEECCEEECCCCCCCCCCHHHHCCEEEECCCCHHHHHCCC
PNLALGSEVAFELNGQETFLRVIGVYKEAAAGGLVGSMPTVNTYTPYTVANDITHTEDGF
CCCEECCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
NTLSIRAAQGVDQDSLKGSLQTYFDALYANNDSHHVAMLDFRKQIEEFNTILGAMSLGIS
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
AIGGISLLVGGIGVMNIMLVSVTERTREIGVRKALGARRRDIRLQFVVEAMIICFIGGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GVLLGGILGLIMSSAIGYISLPPLSGIVIALVFSMAIGLFFGYYPANKAAKLDPIDALRY
HHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC
E
C
>Mature Secondary Structure 
SLAESILLALTSLRSNKMRALLTLLGVIIGIASVIGILTIGKALQDQTLNSLESLGAND
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSAQVEERPDEDSPEPDMFAFSGAANSSGNLIPEETVDTLRDRFAGSITGISVGGMGTQG
HHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCC
TLIGDTADLKSDLLGVNEDYMWMNGVEMNYGRAITQDDVAAQRPVAVIAPDTFNTLFDAN
CEECCHHHHHHHHCCCCCCCEEECCEEECCCCCCCCCCHHHHCCEEEECCCCHHHHHCCC
PNLALGSEVAFELNGQETFLRVIGVYKEAAAGGLVGSMPTVNTYTPYTVANDITHTEDGF
CCCEECCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
NTLSIRAAQGVDQDSLKGSLQTYFDALYANNDSHHVAMLDFRKQIEEFNTILGAMSLGIS
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
AIGGISLLVGGIGVMNIMLVSVTERTREIGVRKALGARRRDIRLQFVVEAMIICFIGGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GVLLGGILGLIMSSAIGYISLPPLSGIVIALVFSMAIGLFFGYYPANKAAKLDPIDALRY
HHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA