Click here to switch to the map view.

The map label for this gene is regX3 [H]

Identifier: 145296659

GI number: 145296659

Start: 2832499

End: 2833224

Strand: Direct

Name: regX3 [H]

Synonym: cgR_2566

Alternate gene names: 145296659

Gene position: 2832499-2833224 (Clockwise)

Preceding gene: 145296654

Following gene: 145296660

Centisome position: 85.47

GC content: 54.13

Gene sequence:

>726_bases
ATGACGAACCCCTCCCCCGCGCTAAATGAAACCCTTTCCGGCAGGGTGCTGATCGTTGAAGATGAGCGCCCTCTTGCTCG
CATGATTTCGCTGTATCTAAGCAAAGCGGGGTTCGATACCACCACGATCCACGACGGCGCAGCTGCTCCAGATAAGGTCG
CTCACCTGCGCCCCGACGTGGTCATTTTGGATCTTGGGCTGCCTGGTCTTGATGGTTTGGAAGTGTGCAAACGCATCCGC
GCGTTCACCGATTGCTACATCCTAATGCTCACCGCCAGGGGTTCAGAGCGGGATCGGATTACAGGTTTGGAAATTGGGGC
TGATGATTACATCACCAAGCCGTTTAATATCCGCGAACTTGTCATTCGTATCCAGTCAGTAATGCGTCGCCCTCGAAAAA
TCGATGAAACCATCCAAAATGGTTTGACCTTGACTTATGGCCACATTGAGCTGGACACCTTGGCGCATGAAGTCACTGTC
AAAGGCGTTGGGGTGACACTGACCCGCACTGAATTCGAGCTGCTTCAAGCCCTCATGCACAAACCCGGAGAGGCAGTATC
TAGGCGCGATCTGGTCAGCCAAGTTTGGGATACCACCTGGGTTGGCGATGAACGCATCGTGGATGTGCACATTGGAAATC
TGCGCCGCAAGCTGGAAGCACCTGCGCCGGGTTCACACTTCATCGACACCATCCGAGGTGTTGGCTACCGGATGGCCTTC
AAATGA

Upstream 100 bases:

>100_bases
CGGCCCTCCACCCGCAATCTACGGTTGAGCGGCCGAGGCCAAGGCAGCCGTTTCTGCTCCTGTTGTTAATCAGGAAACAG
AAAAGGCCATACTTGAAACC

Downstream 100 bases:

>100_bases
CCGCCCTCATTCCGGCCCGCCACAGTCTGACTTTTCGTCTGCTCACCGCGCAGCTTGCTGTGGTGTTGATCAGTCTGCTC
GCAGCCCTGATTGTGGCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTNPSPALNETLSGRVLIVEDERPLARMISLYLSKAGFDTTTIHDGAAAPDKVAHLRPDVVILDLGLPGLDGLEVCKRIR
AFTDCYILMLTARGSERDRITGLEIGADDYITKPFNIRELVIRIQSVMRRPRKIDETIQNGLTLTYGHIELDTLAHEVTV
KGVGVTLTRTEFELLQALMHKPGEAVSRRDLVSQVWDTTWVGDERIVDVHIGNLRRKLEAPAPGSHFIDTIRGVGYRMAF
K

Sequences:

>Translated_241_residues
MTNPSPALNETLSGRVLIVEDERPLARMISLYLSKAGFDTTTIHDGAAAPDKVAHLRPDVVILDLGLPGLDGLEVCKRIR
AFTDCYILMLTARGSERDRITGLEIGADDYITKPFNIRELVIRIQSVMRRPRKIDETIQNGLTLTYGHIELDTLAHEVTV
KGVGVTLTRTEFELLQALMHKPGEAVSRRDLVSQVWDTTWVGDERIVDVHIGNLRRKLEAPAPGSHFIDTIRGVGYRMAF
K
>Mature_240_residues
TNPSPALNETLSGRVLIVEDERPLARMISLYLSKAGFDTTTIHDGAAAPDKVAHLRPDVVILDLGLPGLDGLEVCKRIRA
FTDCYILMLTARGSERDRITGLEIGADDYITKPFNIRELVIRIQSVMRRPRKIDETIQNGLTLTYGHIELDTLAHEVTVK
GVGVTLTRTEFELLQALMHKPGEAVSRRDLVSQVWDTTWVGDERIVDVHIGNLRRKLEAPAPGSHFIDTIRGVGYRMAFK

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=41.3333333333333, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=40.2542372881356, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=39.2857142857143, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=36.1233480176211, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.4801762114537, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.8421052631579, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.1233480176211, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.1838565022422, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=35.7758620689655, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.8947368421053, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.8947368421053, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=31.1688311688312, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=30.8219178082192, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=28.6821705426357, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26908; Mature: 26777

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPSPALNETLSGRVLIVEDERPLARMISLYLSKAGFDTTTIHDGAAAPDKVAHLRPDV
CCCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHCCCCE
VILDLGLPGLDGLEVCKRIRAFTDCYILMLTARGSERDRITGLEIGADDYITKPFNIREL
EEEECCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHH
VIRIQSVMRRPRKIDETIQNGLTLTYGHIELDTLAHEVTVKGVGVTLTRTEFELLQALMH
HHHHHHHHHCCHHHHHHHHCCCEEEECCEEHHHHHHEEEEEECCEEEEHHHHHHHHHHHC
KPGEAVSRRDLVSQVWDTTWVGDERIVDVHIGNLRRKLEAPAPGSHFIDTIRGVGYRMAF
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHCCCCCCHHHHHHHHCCCEEECC
K
C
>Mature Secondary Structure 
TNPSPALNETLSGRVLIVEDERPLARMISLYLSKAGFDTTTIHDGAAAPDKVAHLRPDV
CCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHCCCCE
VILDLGLPGLDGLEVCKRIRAFTDCYILMLTARGSERDRITGLEIGADDYITKPFNIREL
EEEECCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHH
VIRIQSVMRRPRKIDETIQNGLTLTYGHIELDTLAHEVTVKGVGVTLTRTEFELLQALMH
HHHHHHHHHCCHHHHHHHHCCCEEEECCEEHHHHHHEEEEEECCEEEEHHHHHHHHHHHC
KPGEAVSRRDLVSQVWDTTWVGDERIVDVHIGNLRRKLEAPAPGSHFIDTIRGVGYRMAF
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHCCCCCCHHHHHHHHCCCEEECC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA