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The map label for this gene is lrp [H]

Identifier: 145296654

GI number: 145296654

Start: 2829349

End: 2829849

Strand: Direct

Name: lrp [H]

Synonym: cgR_2561

Alternate gene names: 145296654

Gene position: 2829349-2829849 (Clockwise)

Preceding gene: 145296652

Following gene: 145296659

Centisome position: 85.37

GC content: 49.1

Gene sequence:

>501_bases
ATGAATGAATTTCAAATGAAACAAGATCAATCTCCAAAATTAGATTTGGTAGATTGGAAAATTCTCGAACTTTTACAGGT
CGATGCAACAATGCCGAACAAGGACATCGCAGCCAAAGTCGGTATCGCACCGAGCACCTGTCTAGAACGGATCCGGCGAA
TGCGACGAAATGGAACAATCGTCGCCACCCGTGCGCACGTTCGCCCAAGTTTGTTGGGTAGAGGTGAACAGGCTTTTCTT
GGCATCCAAATCCGACCCCACGCCCGTGATACAGCCAATGACTTTGTGCAAAAAGTACTCGCACTTCCCGAAACCCTCGC
GCTCTACAACGTCAGTGGCAGCGAAGACTATCTTGTTCATGTCGCCGTAGCGAACAGCACCGAATTACAATCTTTGATCA
TCGATAAACTGCTCGCACTGCCACAGGTCGCACACTGTCGAACACAACTAATTTTCGGTGAGCCTTGGGTCGCTCCGCTT
CGACAAAGCGACCGACAATAA

Upstream 100 bases:

>100_bases
GCGAATGCGACCCATGATGCTGCGTCCACGTGTACCTCAATTTCTGTTCAAAGAATTTCCAGAAACTAAATGTACGAATA
TGATTCGTTAGACTTCAATC

Downstream 100 bases:

>100_bases
AGCCACCGACATTAAAGCAACAGTCGATCCAGACAAACTACAGGGGTTTACTTCCTCTTAGGTGATTTGTGGAAGTCTTT
ATACGGGGCAAGAAATCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNEFQMKQDQSPKLDLVDWKILELLQVDATMPNKDIAAKVGIAPSTCLERIRRMRRNGTIVATRAHVRPSLLGRGEQAFL
GIQIRPHARDTANDFVQKVLALPETLALYNVSGSEDYLVHVAVANSTELQSLIIDKLLALPQVAHCRTQLIFGEPWVAPL
RQSDRQ

Sequences:

>Translated_166_residues
MNEFQMKQDQSPKLDLVDWKILELLQVDATMPNKDIAAKVGIAPSTCLERIRRMRRNGTIVATRAHVRPSLLGRGEQAFL
GIQIRPHARDTANDFVQKVLALPETLALYNVSGSEDYLVHVAVANSTELQSLIIDKLLALPQVAHCRTQLIFGEPWVAPL
RQSDRQ
>Mature_166_residues
MNEFQMKQDQSPKLDLVDWKILELLQVDATMPNKDIAAKVGIAPSTCLERIRRMRRNGTIVATRAHVRPSLLGRGEQAFL
GIQIRPHARDTANDFVQKVLALPETLALYNVSGSEDYLVHVAVANSTELQSLIIDKLLALPQVAHCRTQLIFGEPWVAPL
RQSDRQ

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=159, Percent_Identity=32.7044025157233, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI87081742, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18632; Mature: 18632

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFQMKQDQSPKLDLVDWKILELLQVDATMPNKDIAAKVGIAPSTCLERIRRMRRNGTI
CCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCE
VATRAHVRPSLLGRGEQAFLGIQIRPHARDTANDFVQKVLALPETLALYNVSGSEDYLVH
EEEECCCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHEEEECCCCCCEEEE
VAVANSTELQSLIIDKLLALPQVAHCRTQLIFGEPWVAPLRQSDRQ
EEECCCHHHHHHHHHHHHHCCHHHHHHHHEEECCCCCCHHHCCCCC
>Mature Secondary Structure
MNEFQMKQDQSPKLDLVDWKILELLQVDATMPNKDIAAKVGIAPSTCLERIRRMRRNGTI
CCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCE
VATRAHVRPSLLGRGEQAFLGIQIRPHARDTANDFVQKVLALPETLALYNVSGSEDYLVH
EEEECCCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHEEEECCCCCCEEEE
VAVANSTELQSLIIDKLLALPQVAHCRTQLIFGEPWVAPLRQSDRQ
EEECCCHHHHHHHHHHHHHCCHHHHHHHHEEECCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]