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The map label for this gene is gsiC [H]

Identifier: 145296650

GI number: 145296650

Start: 2824817

End: 2825782

Strand: Direct

Name: gsiC [H]

Synonym: cgR_2557

Alternate gene names: 145296650

Gene position: 2824817-2825782 (Clockwise)

Preceding gene: 145296649

Following gene: 145296651

Centisome position: 85.23

GC content: 54.76

Gene sequence:

>966_bases
ATGTCCAATCTTTTGAGACTTGTCGGCCGACGGCTCATCGCTTTACCGATCATGATTATTGGCGTCACCCTGCTGGTTTT
CATCGTCATGTCATTCTCTCCTGCCGACCCGGCACGACTTGCCCTAGGCGAATCAGCCTCCCCCGAAGCACTTGAAGCCT
ACCGCGAAGCGAACGGCCTCAACGATCCAATGATGGTTCGCTATTTCGACTTCATCCTCGGCATGCTCAAAGGCGACTTG
GGAACCTCTAGCGGTGGCGTAGCTGTTACCGACATTGTTGCCCGCGCTTTCCCCATCACCCTGCAGCTAACATTCTGGGG
ACTCATCATCGCTGTTGTAGTGGCGTTGATCCTCGGTGTCATCGCCGCTCTATACCGCGACCGCTGGCCTGACCAGTTGA
TTCGCGTGGTCTCCATTGCGGCTCTTGCTACTCCTTCATTCTGGTTGGCTATCTTGCTGATCCAGTGGTTGGGTACTATC
CCTGGAGCCTGGGGTTTCTTCCCAGCACTTGTCACCCGGTGGGTCCCATTCAGCGAAGATCCCGCCACCTACTTCAACAA
CATCGCACTTCCAGCGATTGCGCTGGCAGTCCCCGTTGCAGGTTCTTTGGCCCGCGTTGTTCGTACCTCCATGGTGGAAG
AATTAGACAAGGACTACGTCCGCACAGCAATCGGTGCAGGTATCCCCAAAACTGAAGTTGTTGCCCGCAATGTTCTGCGC
AATGCGCTGATCACCCCAATCACCGTGATTGGTCTTCGCGTTGGTTACCTCATGGGTGGTGCGGTGATCATTGAGATCAT
CTTCAACATCCAAGCAATGGGACAGCTCATCCTAGACGGTGTGACCCGAAATGACGTCTACCTCGTCCAAGGTGTCACCC
TCACCGTTGCCATCGCCTTCATCATCGTCAATATCGCCGTGGACCTGCTCTACGTCCTGGTCAATCCACGTATTAGGAGC
ATCTAG

Upstream 100 bases:

>100_bases
CTCTCCAATTCTTTCCAGTTTCTGGTGTTTTTCTAGCCTGTTAGTTTTCAGCATTTTTCAGCACACTTTTTAAGATCTCA
TCGAAAGCGCGATACCCACT

Downstream 100 bases:

>100_bases
ATGCGCCGTAAACTAACCACCACATTAGAAAACAAGCCCGGTGCACGACTTGGTGGCTTCCGCGCACTTGCACCAACTTC
AAAAATCGCGCTGGTTTTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSNLLRLVGRRLIALPIMIIGVTLLVFIVMSFSPADPARLALGESASPEALEAYREANGLNDPMMVRYFDFILGMLKGDL
GTSSGGVAVTDIVARAFPITLQLTFWGLIIAVVVALILGVIAALYRDRWPDQLIRVVSIAALATPSFWLAILLIQWLGTI
PGAWGFFPALVTRWVPFSEDPATYFNNIALPAIALAVPVAGSLARVVRTSMVEELDKDYVRTAIGAGIPKTEVVARNVLR
NALITPITVIGLRVGYLMGGAVIIEIIFNIQAMGQLILDGVTRNDVYLVQGVTLTVAIAFIIVNIAVDLLYVLVNPRIRS
I

Sequences:

>Translated_321_residues
MSNLLRLVGRRLIALPIMIIGVTLLVFIVMSFSPADPARLALGESASPEALEAYREANGLNDPMMVRYFDFILGMLKGDL
GTSSGGVAVTDIVARAFPITLQLTFWGLIIAVVVALILGVIAALYRDRWPDQLIRVVSIAALATPSFWLAILLIQWLGTI
PGAWGFFPALVTRWVPFSEDPATYFNNIALPAIALAVPVAGSLARVVRTSMVEELDKDYVRTAIGAGIPKTEVVARNVLR
NALITPITVIGLRVGYLMGGAVIIEIIFNIQAMGQLILDGVTRNDVYLVQGVTLTVAIAFIIVNIAVDLLYVLVNPRIRS
I
>Mature_320_residues
SNLLRLVGRRLIALPIMIIGVTLLVFIVMSFSPADPARLALGESASPEALEAYREANGLNDPMMVRYFDFILGMLKGDLG
TSSGGVAVTDIVARAFPITLQLTFWGLIIAVVVALILGVIAALYRDRWPDQLIRVVSIAALATPSFWLAILLIQWLGTIP
GAWGFFPALVTRWVPFSEDPATYFNNIALPAIALAVPVAGSLARVVRTSMVEELDKDYVRTAIGAGIPKTEVVARNVLRN
ALITPITVIGLRVGYLMGGAVIIEIIFNIQAMGQLILDGVTRNDVYLVQGVTLTVAIAFIIVNIAVDLLYVLVNPRIRSI

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=317, Percent_Identity=35.0157728706625, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=33.8235294117647, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=35.5828220858896, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787497, Length=320, Percent_Identity=30.3125, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789888, Length=328, Percent_Identity=30.4878048780488, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=27.9245283018868, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788504, Length=291, Percent_Identity=26.1168384879725, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34721; Mature: 34590

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLLRLVGRRLIALPIMIIGVTLLVFIVMSFSPADPARLALGESASPEALEAYREANGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCC
NDPMMVRYFDFILGMLKGDLGTSSGGVAVTDIVARAFPITLQLTFWGLIIAVVVALILGV
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAALYRDRWPDQLIRVVSIAALATPSFWLAILLIQWLGTIPGAWGFFPALVTRWVPFSED
HHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
PATYFNNIALPAIALAVPVAGSLARVVRTSMVEELDKDYVRTAIGAGIPKTEVVARNVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NALITPITVIGLRVGYLMGGAVIIEIIFNIQAMGQLILDGVTRNDVYLVQGVTLTVAIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHH
IIVNIAVDLLYVLVNPRIRSI
HHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SNLLRLVGRRLIALPIMIIGVTLLVFIVMSFSPADPARLALGESASPEALEAYREANGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCC
NDPMMVRYFDFILGMLKGDLGTSSGGVAVTDIVARAFPITLQLTFWGLIIAVVVALILGV
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAALYRDRWPDQLIRVVSIAALATPSFWLAILLIQWLGTIPGAWGFFPALVTRWVPFSED
HHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
PATYFNNIALPAIALAVPVAGSLARVVRTSMVEELDKDYVRTAIGAGIPKTEVVARNVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NALITPITVIGLRVGYLMGGAVIIEIIFNIQAMGQLILDGVTRNDVYLVQGVTLTVAIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHH
IIVNIAVDLLYVLVNPRIRSI
HHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]