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The map label for this gene is celR [H]

Identifier: 145296626

GI number: 145296626

Start: 2799829

End: 2800911

Strand: Reverse

Name: celR [H]

Synonym: cgR_2534

Alternate gene names: 145296626

Gene position: 2800911-2799829 (Counterclockwise)

Preceding gene: 145296630

Following gene: 145296620

Centisome position: 84.51

GC content: 55.4

Gene sequence:

>1083_bases
ATGATTATGGGTAGGAAACAACAATACGGAACCCTCGCGTCCATCGCCGCGAAACTAGGTGTCTCAAGGACCACGGTGTC
TAATGCCTACAACCGGCCGGAGCAACTCTCCGCAGAACTTCGCCAACGCATCCTCGACACCGCTGAAGATATGGGCTATC
TCGGCCCTGATCCGGTAGCCCGGAGCCTTCGTACACGCAGAGCAGGCGCGATCGGTGTGCTACTTACCGAGGACCTCACT
TATGCCTTCGAAGATATGGCTTCCGTGGACTTTCTTGCCGGGGTGGCTGAAGCGGCCGGAGACACCCAACTAACGCTGAT
TCCTGCCTCGCCCGCGAGCAGCGTTGACCATGTCTCGGCTCAACAATTAGTCAACAACGCTGCAGTTGACGGAGTGGTTA
TTTACTCCGTCGCCAAGGGGGATCCACACATCAATGCCATCCGTGCCCGTGGTTTGCCCGCAGTCATCGCCGACCAGCCT
GCACGCGAAGAAGGCCTGCCGTTTATTGCCCCAAATAACCGCAAAGCCATCGCCCCTGCAGCTCAAGCGCTAATCGACGC
CGGCCACCGTAAAATCGGCATCCTGTCCATCCGCCTAGACCGCGCAAACAACGACGGCGAAGTCACCCGCGAGCGCCTCG
AAAACGCCCAATACCAGGTACAACGCGACCGAGTCGGGGGTGCCATGGAAGTCTTTATCGAAGCGGGAATCGATCCCGAC
ACCGTGCCGATCATGGAATGCTGGATCAACAACCGCCAACACAACTTCGAAGTGGCCAAAGAACTTCTAGAAACACACCC
AGACCTCACCGCAGTACTCTGTACCGTCGATGCACTGGCATTCGGCGTTCTGGAATACCTTAAAAGCGTAGGTAAATCAG
TGCCTGCAGATCTATCCCTCACTGGTTTCGATGGCACCCACATGGCACTCGCACGGGATCTCACCACCGTCATCCAACCT
AATAAACTTAAAGGGTTCAAAGCCGGCGAAACACTGTTGAAAATGATTGACAAAGAATACGTGGAACCAGAAGTGGAATT
GGAAACTTTCTTCCACCCAGGTTCCACGGTTGCGCCAATCTAG

Upstream 100 bases:

>100_bases
TAAATGCTTATTGAAAACAGCTGTCAACATGAAAACTTATTGAAAATAGCAAAATCGCGTTAGACCTCGGATACGCCATA
GGGGTAACTGGTAGATTGAA

Downstream 100 bases:

>100_bases
GCTTGTGGCACTTTTCGTGCGTTTAGGCTCTCTTAAATCCCCAATCGCACGCTTTCCGCATACTGCATGCGGTGGTAGGC
GAGTTTCTCTAGGAAAATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIMGRKQQYGTLASIAAKLGVSRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVARSLRTRRAGAIGVLLTEDLT
YAFEDMASVDFLAGVAEAAGDTQLTLIPASPASSVDHVSAQQLVNNAAVDGVVIYSVAKGDPHINAIRARGLPAVIADQP
AREEGLPFIAPNNRKAIAPAAQALIDAGHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVGGAMEVFIEAGIDPD
TVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSVPADLSLTGFDGTHMALARDLTTVIQP
NKLKGFKAGETLLKMIDKEYVEPEVELETFFHPGSTVAPI

Sequences:

>Translated_360_residues
MIMGRKQQYGTLASIAAKLGVSRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVARSLRTRRAGAIGVLLTEDLT
YAFEDMASVDFLAGVAEAAGDTQLTLIPASPASSVDHVSAQQLVNNAAVDGVVIYSVAKGDPHINAIRARGLPAVIADQP
AREEGLPFIAPNNRKAIAPAAQALIDAGHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVGGAMEVFIEAGIDPD
TVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSVPADLSLTGFDGTHMALARDLTTVIQP
NKLKGFKAGETLLKMIDKEYVEPEVELETFFHPGSTVAPI
>Mature_360_residues
MIMGRKQQYGTLASIAAKLGVSRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVARSLRTRRAGAIGVLLTEDLT
YAFEDMASVDFLAGVAEAAGDTQLTLIPASPASSVDHVSAQQLVNNAAVDGVVIYSVAKGDPHINAIRARGLPAVIADQP
AREEGLPFIAPNNRKAIAPAAQALIDAGHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVGGAMEVFIEAGIDPD
TVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSVPADLSLTGFDGTHMALARDLTTVIQP
NKLKGFKAGETLLKMIDKEYVEPEVELETFFHPGSTVAPI

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=348, Percent_Identity=27.0114942528736, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994940, Length=359, Percent_Identity=25.0696378830084, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787948, Length=345, Percent_Identity=26.9565217391304, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=24.251497005988, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=23.7785016286645, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787906, Length=290, Percent_Identity=24.4827586206897, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38877; Mature: 38877

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMGRKQQYGTLASIAAKLGVSRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVA
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RSLRTRRAGAIGVLLTEDLTYAFEDMASVDFLAGVAEAAGDTQLTLIPASPASSVDHVSA
HHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
QQLVNNAAVDGVVIYSVAKGDPHINAIRARGLPAVIADQPAREEGLPFIAPNNRKAIAPA
HHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCEEECCCCCHHCCCCEECCCCCCCHHHH
AQALIDAGHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVGGAMEVFIEAGIDPD
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHEECCCCCC
TVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSVPADLSL
CHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
TGFDGTHMALARDLTTVIQPNKLKGFKAGETLLKMIDKEYVEPEVELETFFHPGSTVAPI
ECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MIMGRKQQYGTLASIAAKLGVSRTTVSNAYNRPEQLSAELRQRILDTAEDMGYLGPDPVA
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RSLRTRRAGAIGVLLTEDLTYAFEDMASVDFLAGVAEAAGDTQLTLIPASPASSVDHVSA
HHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
QQLVNNAAVDGVVIYSVAKGDPHINAIRARGLPAVIADQPAREEGLPFIAPNNRKAIAPA
HHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCEEECCCCCHHCCCCEECCCCCCCHHHH
AQALIDAGHRKIGILSIRLDRANNDGEVTRERLENAQYQVQRDRVGGAMEVFIEAGIDPD
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHEECCCCCC
TVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTVDALAFGVLEYLKSVGKSVPADLSL
CHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
TGFDGTHMALARDLTTVIQPNKLKGFKAGETLLKMIDKEYVEPEVELETFFHPGSTVAPI
ECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]