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The map label for this gene is tipA [H]

Identifier: 145296604

GI number: 145296604

Start: 2773981

End: 2774736

Strand: Reverse

Name: tipA [H]

Synonym: cgR_2512

Alternate gene names: 145296604

Gene position: 2774736-2773981 (Counterclockwise)

Preceding gene: 145296605

Following gene: 145296603

Centisome position: 83.72

GC content: 54.37

Gene sequence:

>756_bases
ATGACAGATCGAACCATCGGCGAGGCTGCTGAACTACTCGGTGTCACCACCCGCACACTGCGGCATTGGGACAGCATCGG
GTTGCTTCAACCGAGCTGGCGAACCACAACGGATTATCGCCTTTACACGGAAGACGATGTCGAGCGCGCCCTGCAGATTC
TTATTTACAGGGCCGCCGGAATCGCGTTGAAGGATATCGCGCAGGTGCTTGATCAGCCGGATTCGGCCAATCAGCACCTG
CGTCGCCAGCGGGAACTCCTAGTGGAACAGATCGGTCAGCTGCATCGGATGGTCCGGGCAGTAGATGAAATCCTTGGAAA
GGATGCGATTAGCGTGAAGGAAAAGATTGAGATCTTCGGCGAGGATCTGCCCAAGTACCAAGAGGAGGCTTTCCAGCGCT
GGGGCGACACCCCGGAGTGGAAAGAATCCCAAAAGATCCAAAAGAAGATGACCAAGGAGGATTTTCAGAGGGCGAAAGAT
GAACATGAGGGGTTCGTCGAAAAGCTTATCGACGCCTCCCTGCGCGGCGTCGCGCCCGGCTCTGCCGAGGGCAATGAGCT
AGCGCTTGCGCACCGCGCAAGCATCGGTCAGTGGTACACCGTGAGTGCAAACAAGCAAGTAATTTTGGCTCGGATGTACG
TGGAAGATGAGCGTTTTAACGCAACTTACAAAGGACACGCCTCATATCTTTTAACACTTATTGAAGCATTAGCGCAGGTA
GAAGGCGTGGACTTGGAGAATGTGGAGTGGGAATAA

Upstream 100 bases:

>100_bases
CGGATGGCACTTTCCGTACCTGGAAGGTAGTTGCCCGTGGCAGAAACAACTAGAGAAACCTCTTGACCTTCACGCGACGT
CAAGGATTTAACTAACAGTC

Downstream 100 bases:

>100_bases
TCCCAATTTCAACTCTTTCAGTACATTCACAGTTAGTATTCAGTGGTGTTGAAGTTCCAGGGTGTTCACTAGTGAGAAGT
TAATTATTCCGCCAATGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTDRTIGEAAELLGVTTRTLRHWDSIGLLQPSWRTTTDYRLYTEDDVERALQILIYRAAGIALKDIAQVLDQPDSANQHL
RRQRELLVEQIGQLHRMVRAVDEILGKDAISVKEKIEIFGEDLPKYQEEAFQRWGDTPEWKESQKIQKKMTKEDFQRAKD
EHEGFVEKLIDASLRGVAPGSAEGNELALAHRASIGQWYTVSANKQVILARMYVEDERFNATYKGHASYLLTLIEALAQV
EGVDLENVEWE

Sequences:

>Translated_251_residues
MTDRTIGEAAELLGVTTRTLRHWDSIGLLQPSWRTTTDYRLYTEDDVERALQILIYRAAGIALKDIAQVLDQPDSANQHL
RRQRELLVEQIGQLHRMVRAVDEILGKDAISVKEKIEIFGEDLPKYQEEAFQRWGDTPEWKESQKIQKKMTKEDFQRAKD
EHEGFVEKLIDASLRGVAPGSAEGNELALAHRASIGQWYTVSANKQVILARMYVEDERFNATYKGHASYLLTLIEALAQV
EGVDLENVEWE
>Mature_250_residues
TDRTIGEAAELLGVTTRTLRHWDSIGLLQPSWRTTTDYRLYTEDDVERALQILIYRAAGIALKDIAQVLDQPDSANQHLR
RQRELLVEQIGQLHRMVRAVDEILGKDAISVKEKIEIFGEDLPKYQEEAFQRWGDTPEWKESQKIQKKMTKEDFQRAKDE
HEGFVEKLIDASLRGVAPGSAEGNELALAHRASIGQWYTVSANKQVILARMYVEDERFNATYKGHASYLLTLIEALAQVE
GVDLENVEWE

Specific function: Transcriptional activator. Is activated when bound to the antibiotic thiostrepton [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 28767; Mature: 28636

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRTIGEAAELLGVTTRTLRHWDSIGLLQPSWRTTTDYRLYTEDDVERALQILIYRAAG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHC
IALKDIAQVLDQPDSANQHLRRQRELLVEQIGQLHRMVRAVDEILGKDAISVKEKIEIFG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
EDLPKYQEEAFQRWGDTPEWKESQKIQKKMTKEDFQRAKDEHEGFVEKLIDASLRGVAPG
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAEGNELALAHRASIGQWYTVSANKQVILARMYVEDERFNATYKGHASYLLTLIEALAQV
CCCCCCEEHHHHHCCCCEEEECCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EGVDLENVEWE
CCCCCCCCCCC
>Mature Secondary Structure 
TDRTIGEAAELLGVTTRTLRHWDSIGLLQPSWRTTTDYRLYTEDDVERALQILIYRAAG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHC
IALKDIAQVLDQPDSANQHLRRQRELLVEQIGQLHRMVRAVDEILGKDAISVKEKIEIFG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
EDLPKYQEEAFQRWGDTPEWKESQKIQKKMTKEDFQRAKDEHEGFVEKLIDASLRGVAPG
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAEGNELALAHRASIGQWYTVSANKQVILARMYVEDERFNATYKGHASYLLTLIEALAQV
CCCCCCEEHHHHHCCCCEEEECCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EGVDLENVEWE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]