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The map label for this gene is clpX

Identifier: 145296354

GI number: 145296354

Start: 2499727

End: 2501007

Strand: Reverse

Name: clpX

Synonym: cgR_2269

Alternate gene names: 145296354

Gene position: 2501007-2499727 (Counterclockwise)

Preceding gene: 145296356

Following gene: 145296353

Centisome position: 75.46

GC content: 52.77

Gene sequence:

>1281_bases
ATGGCACGTATGCAGGAAAGCGCCGATCTGCTCAAATGTTCCTTCTGCGGAAAGAGCCAAAAGCAGGTAAAAAAACTCAT
CGCGGGTGGCGCCGTATATATCTGTGATGAGTGCATTGAGCTGTGCAACGAGATTATTGAAGAAGAACTCGGTCAAGCTC
AACACGACGAGCAGGAGCGCAACGAACTCCCCAAGCCGTCGGAGATCTCAGCCTTCCTTGATACCTATGTCATCGGGCAG
GATCCGGCAAAACGTATCCTGTCGGTTGCGGTGTACAACCATTACAAGCGTCTCCGCGCATCGGAAACCATCGGTCGTCG
CAGGAATGACGAGCCTGAAACCGAACTGGTTAAGTCCAATATTTTGATGCTCGGCCCCACTGGTTCCGGCAAGACTTTCC
TTGCCCAGACTTTGGCAAAGCTGCTGGATGTTCCTTTTGCTATTGCGGATGCCACCTCACTGACCGAAGCTGGTTATGTG
GGTGAAGATGTAGAAAACATCTTGCTCAAACTGCTTCAGGCTGCTGATTTTGATGTGGAACGTGCACAGCGTGGCATCAT
TTACATCGATGAAGTGGACAAGATTTCCCGCAAATCTGAAAACCCATCGATTACTCGCGATGTTTCCGGTGAGGGCGTGC
AGCAGGCACTGCTGAAGATTTTGGAGGGCACTGTCGCCGCGATCCCACCGCAAGGCGGACGCAAGCACCCCAACCAGGAT
TTCATCCAGCTGGATACCACCAACATTTTGTTCATCGTTGCTGGCGCGTTCTCTGGTCTGGAGAAGGTCATCGCAGACCG
CAATGGCAAAAAGGGGTTGGGCTTCGGTGTGGAGGTCTCTTCCAAGAAGGAAGAAGCCGACATCGTGGATATCTTCAAGG
ATGTGCGCCCTGAGGACCTGGTGAAGTTTGGTCTCATCCCAGAGTTCATTGGCCGTTTGCCAGTTGTTGCCACCGTGTCT
AACCTGGATCAAAAATCTTTGGTCAAGGTCCTCACGGAGCCCCGTAACTCTTTGGTGAAGCAGTACCAGCGTCTGTTTGA
AATGGATGACGCGGTGTTGACCTTTACTGATGATGCTCTGGAAGAGATCGCTAATCAGGCACTCGAGCGCAAGACTGGTG
CCCGTGGCCTGCGCGCGATCATGGAAGAGATCTTGGTTCCGATCATGTATGATCTCCCAGACCGCGAAGACGTCGGTGAA
GTCATCATCAACGGTGCCGTCGCCAGGGGCGAAGCCGAACCAGAGATGTTGGAAGCTGTCGCAGAAGAAAAGACCGCGTA
G

Upstream 100 bases:

>100_bases
ACAGGTAAAGCGCTAAGATGGAACAACCCATTGCCAATATTGTTGGTTAGAGTTGTACGCAGTAAATCTTTTCAATCGTG
GAAGCGGGTCTCACAGTCTA

Downstream 100 bases:

>100_bases
TTGGCAGGAGTTATCACCGGTTTCGCCATCATCCTGTCGGTCATCGGCGTCGGATTTCTTCTGGCAAAGCTGGGGGTCAT
CAATGATGACAAACAGCGCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQ
DPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYV
GEDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEADIVDIFKDVRPEDLVKFGLIPEFIGRLPVVATVS
NLDQKSLVKVLTEPRNSLVKQYQRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDREDVGE
VIINGAVARGEAEPEMLEAVAEEKTA

Sequences:

>Translated_426_residues
MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQ
DPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYV
GEDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEADIVDIFKDVRPEDLVKFGLIPEFIGRLPVVATVS
NLDQKSLVKVLTEPRNSLVKQYQRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDREDVGE
VIINGAVARGEAEPEMLEAVAEEKTA
>Mature_425_residues
ARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQD
PAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVG
EDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQDF
IQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEADIVDIFKDVRPEDLVKFGLIPEFIGRLPVVATVSN
LDQKSLVKVLTEPRNSLVKQYQRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDREDVGEV
IINGAVARGEAEPEMLEAVAEEKTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=514, Percent_Identity=38.9105058365759, Blast_Score=322, Evalue=6e-88,
Organism=Escherichia coli, GI1786642, Length=426, Percent_Identity=60.7981220657277, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=110, Percent_Identity=44.5454545454545, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=317, Percent_Identity=46.6876971608833, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71982908, Length=317, Percent_Identity=46.6876971608833, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=396, Percent_Identity=39.1414141414141, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=257, Percent_Identity=40.4669260700389, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=433, Percent_Identity=39.9538106235566, Blast_Score=266, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24648291, Length=334, Percent_Identity=49.1017964071856, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24648289, Length=334, Percent_Identity=49.1017964071856, Blast_Score=305, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_CORGB (A4QGA7)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001139175.1
- ProteinModelPortal:   A4QGA7
- STRING:   A4QGA7
- GeneID:   4993930
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2269
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46958; Mature: 46827

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQER
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
NELPKPSEISAFLDTYVIGQDPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSN
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
ILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVE
EEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
HHHCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCC
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEADIVDIFKDVRPEDL
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHH
VKFGLIPEFIGRLPVVATVSNLDQKSLVKVLTEPRNSLVKQYQRLFEMDDAVLTFTDDAL
HHHCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
EEIANQALERKTGARGLRAIMEEILVPIMYDLPDREDVGEVIINGAVARGEAEPEMLEAV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHCCCCCHHHHHHH
AEEKTA
HHHCCC
>Mature Secondary Structure 
ARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQER
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
NELPKPSEISAFLDTYVIGQDPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSN
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
ILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVE
EEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
HHHCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCC
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEADIVDIFKDVRPEDL
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHH
VKFGLIPEFIGRLPVVATVSNLDQKSLVKVLTEPRNSLVKQYQRLFEMDDAVLTFTDDAL
HHHCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
EEIANQALERKTGARGLRAIMEEILVPIMYDLPDREDVGEVIINGAVARGEAEPEMLEAV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHCCCCCHHHHHHH
AEEKTA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA