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The map label for this gene is hrcA

Identifier: 145296246

GI number: 145296246

Start: 2385563

End: 2386591

Strand: Reverse

Name: hrcA

Synonym: cgR_2163

Alternate gene names: 145296246

Gene position: 2386591-2385563 (Counterclockwise)

Preceding gene: 145296247

Following gene: 145296245

Centisome position: 72.01

GC content: 57.34

Gene sequence:

>1029_bases
ATGGTGAGTGCAACAGAGAAACGTAGATACGAAGTGTTGCGGGCCATCGTCGCTGATTACATTGCGTCTCAGGAACCTGT
CGGATCGAAGTCACTCCTCGAGCGCCATAAGCTCAACGTGAGTTCTGCGACGATCCGCAACGATATGTCGGTGCTGGAAT
CCGATGGCTTTATCGTCCAGGAGCATGCAAGTTCTGGCCGGGTACCAACCGAAAGGGGTTACCGCCTTTTTGTTGATTCC
ATCCATGACATCAAACCGCTGTCGCTGGCGGAACGGCGCGCTATTTTGGGCTTCCTTGAAGGGGGAGTGGACTTAGAGGA
CGTGCTGCGCAGGTCTGTGCAGCTGTTGTCTCAGCTCACCCATCAGGCTGCCGTGGTGCAGCTGCCCACCCTGAAAACAG
CGCGCGTGAAGCACTGCGAGGTGGTGCCGCTGTCGCCGATGCGCTTGCTGCTGGTGCTCATTACCGATACTGGCCGTGTA
GATCAGCGCAACGTGGAACTTGAGGAACCGCTGGCGGCGGAAGAAGTTAATGTGCTGCGCGATCTGCTCAACGGCGCGCT
AGGGGAGAAAACGCTGACGGCTGCATCAGATGCGCTGGAGGAGTTGGCTCAGCAAGCCCCAACCGATATTCGTGATGCCA
TGCGCCGCTGCTGCGATGTGCTGGTGAACACGCTTGTCGATCAACCCTCTGACCGCCTGATCCTCGCCGGCACCTCAAAC
CTCACCCGCTTAAGCCGGGAAACCTCCGCGAGCCTGCCCATGGTTTTAGAAGCCTTGGAAGAGCAGGTGGTCATGTTGAA
ACTGCTGTCCAATGTCACTGATCTTGACCAAGTGCGCGTGCATATTGGCGGCGAAAATGAAGACATTGAGCTGCGCAGCG
CAACGGTGATTACCACCGGTTACGGCTCCCAGGGCAGCGCACTGGGCGGATTGGGGGTGGTTGGCCCCACCTATATGGAC
TACTCGGGAACAATTTCTAAGGTGTCCGCCGTTGCTAAGTATGTTGGTCGTGTGCTCGCTGGCGAATAG

Upstream 100 bases:

>100_bases
CAACCTGGCGGTGACCGATGCGGGACGTTTGCTTGCCGACGGCATCATCGCCGACATTTTGCTTAGTGAAGAAGACTAAA
TATTTAGTAGGGTTACAGAC

Downstream 100 bases:

>100_bases
CTGCGGGTATAGTTGGCCATTTGTTTTGATTAATCTGTTTAGAAGCTAAAGGAAGTATCACCCACCGTGGCACGTGACTA
TTACGGCATTCTCGGCGTCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVSATEKRRYEVLRAIVADYIASQEPVGSKSLLERHKLNVSSATIRNDMSVLESDGFIVQEHASSGRVPTERGYRLFVDS
IHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLTHQAAVVQLPTLKTARVKHCEVVPLSPMRLLLVLITDTGRV
DQRNVELEEPLAAEEVNVLRDLLNGALGEKTLTAASDALEELAQQAPTDIRDAMRRCCDVLVNTLVDQPSDRLILAGTSN
LTRLSRETSASLPMVLEALEEQVVMLKLLSNVTDLDQVRVHIGGENEDIELRSATVITTGYGSQGSALGGLGVVGPTYMD
YSGTISKVSAVAKYVGRVLAGE

Sequences:

>Translated_342_residues
MVSATEKRRYEVLRAIVADYIASQEPVGSKSLLERHKLNVSSATIRNDMSVLESDGFIVQEHASSGRVPTERGYRLFVDS
IHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLTHQAAVVQLPTLKTARVKHCEVVPLSPMRLLLVLITDTGRV
DQRNVELEEPLAAEEVNVLRDLLNGALGEKTLTAASDALEELAQQAPTDIRDAMRRCCDVLVNTLVDQPSDRLILAGTSN
LTRLSRETSASLPMVLEALEEQVVMLKLLSNVTDLDQVRVHIGGENEDIELRSATVITTGYGSQGSALGGLGVVGPTYMD
YSGTISKVSAVAKYVGRVLAGE
>Mature_342_residues
MVSATEKRRYEVLRAIVADYIASQEPVGSKSLLERHKLNVSSATIRNDMSVLESDGFIVQEHASSGRVPTERGYRLFVDS
IHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLTHQAAVVQLPTLKTARVKHCEVVPLSPMRLLLVLITDTGRV
DQRNVELEEPLAAEEVNVLRDLLNGALGEKTLTAASDALEELAQQAPTDIRDAMRRCCDVLVNTLVDQPSDRLILAGTSN
LTRLSRETSASLPMVLEALEEQVVMLKLLSNVTDLDQVRVHIGGENEDIELRSATVITTGYGSQGSALGGLGVVGPTYMD
YSGTISKVSAVAKYVGRVLAGE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_CORGB (A4QFZ9)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001139067.1
- ProteinModelPortal:   A4QFZ9
- SMR:   A4QFZ9
- STRING:   A4QFZ9
- GeneID:   4992037
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2163
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 37191; Mature: 37191

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSATEKRRYEVLRAIVADYIASQEPVGSKSLLERHKLNVSSATIRNDMSVLESDGFIVQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEE
EHASSGRVPTERGYRLFVDSIHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLT
ECCCCCCCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
HQAAVVQLPTLKTARVKHCEVVPLSPMRLLLVLITDTGRVDQRNVELEEPLAAEEVNVLR
HHHHHEECCCCCHHCCCCCEECCCCHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
DLLNGALGEKTLTAASDALEELAQQAPTDIRDAMRRCCDVLVNTLVDQPSDRLILAGTSN
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCH
LTRLSRETSASLPMVLEALEEQVVMLKLLSNVTDLDQVRVHIGGENEDIELRSATVITTG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCEEEEEEEEEEEC
YGSQGSALGGLGVVGPTYMDYSGTISKVSAVAKYVGRVLAGE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSATEKRRYEVLRAIVADYIASQEPVGSKSLLERHKLNVSSATIRNDMSVLESDGFIVQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEE
EHASSGRVPTERGYRLFVDSIHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLT
ECCCCCCCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
HQAAVVQLPTLKTARVKHCEVVPLSPMRLLLVLITDTGRVDQRNVELEEPLAAEEVNVLR
HHHHHEECCCCCHHCCCCCEECCCCHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
DLLNGALGEKTLTAASDALEELAQQAPTDIRDAMRRCCDVLVNTLVDQPSDRLILAGTSN
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCH
LTRLSRETSASLPMVLEALEEQVVMLKLLSNVTDLDQVRVHIGGENEDIELRSATVITTG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCEEEEEEEEEEEC
YGSQGSALGGLGVVGPTYMDYSGTISKVSAVAKYVGRVLAGE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA