| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is glmS [H]
Identifier: 145296226
GI number: 145296226
Start: 2364241
End: 2366118
Strand: Reverse
Name: glmS [H]
Synonym: cgR_2143
Alternate gene names: 145296226
Gene position: 2366118-2364241 (Counterclockwise)
Preceding gene: 145296227
Following gene: 145296223
Centisome position: 71.39
GC content: 53.78
Gene sequence:
>1878_bases ATGCGCATGTGTGGAATTGTTGGATATATTGGCCAGGCGGGCGACTCCCGTGATTACTTTGCGCTTGACGTCGTTTTAGA AGGACTGCGCCGACTTGAATACCGCGGTTATGATTCCGCAGGTGTAGCTGTTCATGCGAACGGTGAAATCAGCTACCGAA AGAAGGCTGGAAAGGTAGCTGCGCTGGACGCTGAGATCGCTCGCGCTCCTTTGGCGGATTCCATTTTGGCTATTGGTCAC ACCCGGTGGGCAACTCACGGTGGACCAACCGATGCAAATGCACACCCCCATGTTGTTGATGGCGGCAAGTTAGCTGTCGT ACACAACGGTATTATTGAAAACTTTGCAGAGCTGCGCGCAGAGCTTTCAGCTAAGGGCTACAACTTTGTTTCCGTTACTG ACACTGAAGTTGCCGCCACATTGCTGGCAGAAATCTACAACACCCAGGCTAATGGCGATCTGACCAAGGCTATGCAGCTT ACTGGTCAGCGTCTTGAGGGTGCGTTCACCCTGCTGGCTATCCATGCTGATCATGATGATCGTATTGTTGCAGCGCGCCG TAACTCTCCTTTGGTTATTGGCTTGGGTGAAGGCGAAAACTTCCTCGGCTCTGACGTTTCTGGCTTCATCGATTACACCC GCAAGGCTGTTGAGATGGGCAACGATCAGATTGTGACCATCACTGCGAACGACTACCAGATCACCAACTTCGATGGTTCT GAGGCAACCGGAAAACCTTTCGACGTGGAGTGGGATGCGGCTGCTGCTGAAAAGGGTGGCTTTGATTCCTTCATGGATAA GGAAATCCACGACCAGCCAGCTGCAGTGCGTGACACCCTCCTCGGACGTTTAGATGAGGATGGCAAGCTGGTCCTTGATG AGCTTCGTATTGATGAAGCCACCTTGCGCAGTGTAAACAAGATCATCGTTGTTGCTTGTGGTACCGCAGCTTATGCAGGT CAGGTTGCTCGTTATGCCATTGAGCACTGGTGCCGTATCCCAACCGAGGTCGAGTTGGCGCACGAGTTCCGTTACCGCGA TCCAATCGTTAATGAAAAGACTCTGGTCGTAGCATTGTCTCAGTCTGGTGAGACCATGGATACCCTCATGGCTGTTCGCC ACGCGCGCGAGCAGGGCGCGAAGGTTATCGCGATCTGTAACACCGTTGGTTCCACTCTTCCACGTGAAGCAGATGCGTCC CTGTACACCTACGCAGGACCTGAGATCGCTGTGGCATCCACCAAGGCGTTCTTGGCGCAGATCACTGCTTCTTACTTGCT TGGCCTGTACCTGGCTCAGCTGCGCGGCAACAAGTTCGCTGATGAGGTTTCTTCCATTCTGGACAGCCTGCGTGAGATGC CTGAGAAGATTCAGCAGGTCATCGATGCAGAAGAGCAGATCAAGAAGCTTGGCCAGGATATGTCGGATGCTAAGTCTGTG CTGTTCTTGGGTCGCCACGTTGGTTTCCCAGTTGCACTTGAGGGTGCGTTGAAGCTCAAGGAGATCGCTTACCTACACGC GGAAGGTTTCGCTGCGGGCGAGCTCAAGCACGGCCCAATCGCTTTGGTTGAGGAAGGCCAGCCGGTCTTCGTTATCGTGC CTTCACCTCGTGGTCGCGATTCCCTGCACTCCAAGGTTGTCTCCAACATTCAGGAGATCCGTGCACGTGGCGCTGTCACC ATCGTGATTGCAGAGGAAGGCGATGAGGCTGTTAACGATTATGCCAACTTCATCATCCGCATTCCTCAGGCCCCAACCCT GATGCAGCCTCTGCTGTCCACCGTGCCTTTGCAGATCTTCGCGTGCGCTGTGGCAACCGCAAAGGGTTACAACGTGGATC AGCCTCGTAACCTGGCAAAGTCTGTCACCGTCGAATAA
Upstream 100 bases:
>100_bases TTGCGTGCTGCAACTTAATTATGGTCCTCCCAGCTCAGTGTGCTGTGTGGATTGTTTATTCTCGTCCATTAAGTGATCGA GAAAAAGTTGTTGTAAAGTC
Downstream 100 bases:
>100_bases AAAGATTTCGCTTCTCGACGCCAAGTGCCGCCCCAAGGGGCGGCACTTGTGGTGTTTTTAGCGACGGTTGAAGCGCAGAT CAACGCCTAGATCATCGCAG
Product: glucosamine--fructose-6-phosphate aminotransferase
Products: NA
Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]
Number of amino acids: Translated: 625; Mature: 625
Protein sequence:
>625_residues MRMCGIVGYIGQAGDSRDYFALDVVLEGLRRLEYRGYDSAGVAVHANGEISYRKKAGKVAALDAEIARAPLADSILAIGH TRWATHGGPTDANAHPHVVDGGKLAVVHNGIIENFAELRAELSAKGYNFVSVTDTEVAATLLAEIYNTQANGDLTKAMQL TGQRLEGAFTLLAIHADHDDRIVAARRNSPLVIGLGEGENFLGSDVSGFIDYTRKAVEMGNDQIVTITANDYQITNFDGS EATGKPFDVEWDAAAAEKGGFDSFMDKEIHDQPAAVRDTLLGRLDEDGKLVLDELRIDEATLRSVNKIIVVACGTAAYAG QVARYAIEHWCRIPTEVELAHEFRYRDPIVNEKTLVVALSQSGETMDTLMAVRHAREQGAKVIAICNTVGSTLPREADAS LYTYAGPEIAVASTKAFLAQITASYLLGLYLAQLRGNKFADEVSSILDSLREMPEKIQQVIDAEEQIKKLGQDMSDAKSV LFLGRHVGFPVALEGALKLKEIAYLHAEGFAAGELKHGPIALVEEGQPVFVIVPSPRGRDSLHSKVVSNIQEIRARGAVT IVIAEEGDEAVNDYANFIIRIPQAPTLMQPLLSTVPLQIFACAVATAKGYNVDQPRNLAKSVTVE
Sequences:
>Translated_625_residues MRMCGIVGYIGQAGDSRDYFALDVVLEGLRRLEYRGYDSAGVAVHANGEISYRKKAGKVAALDAEIARAPLADSILAIGH TRWATHGGPTDANAHPHVVDGGKLAVVHNGIIENFAELRAELSAKGYNFVSVTDTEVAATLLAEIYNTQANGDLTKAMQL TGQRLEGAFTLLAIHADHDDRIVAARRNSPLVIGLGEGENFLGSDVSGFIDYTRKAVEMGNDQIVTITANDYQITNFDGS EATGKPFDVEWDAAAAEKGGFDSFMDKEIHDQPAAVRDTLLGRLDEDGKLVLDELRIDEATLRSVNKIIVVACGTAAYAG QVARYAIEHWCRIPTEVELAHEFRYRDPIVNEKTLVVALSQSGETMDTLMAVRHAREQGAKVIAICNTVGSTLPREADAS LYTYAGPEIAVASTKAFLAQITASYLLGLYLAQLRGNKFADEVSSILDSLREMPEKIQQVIDAEEQIKKLGQDMSDAKSV LFLGRHVGFPVALEGALKLKEIAYLHAEGFAAGELKHGPIALVEEGQPVFVIVPSPRGRDSLHSKVVSNIQEIRARGAVT IVIAEEGDEAVNDYANFIIRIPQAPTLMQPLLSTVPLQIFACAVATAKGYNVDQPRNLAKSVTVE >Mature_625_residues MRMCGIVGYIGQAGDSRDYFALDVVLEGLRRLEYRGYDSAGVAVHANGEISYRKKAGKVAALDAEIARAPLADSILAIGH TRWATHGGPTDANAHPHVVDGGKLAVVHNGIIENFAELRAELSAKGYNFVSVTDTEVAATLLAEIYNTQANGDLTKAMQL TGQRLEGAFTLLAIHADHDDRIVAARRNSPLVIGLGEGENFLGSDVSGFIDYTRKAVEMGNDQIVTITANDYQITNFDGS EATGKPFDVEWDAAAAEKGGFDSFMDKEIHDQPAAVRDTLLGRLDEDGKLVLDELRIDEATLRSVNKIIVVACGTAAYAG QVARYAIEHWCRIPTEVELAHEFRYRDPIVNEKTLVVALSQSGETMDTLMAVRHAREQGAKVIAICNTVGSTLPREADAS LYTYAGPEIAVASTKAFLAQITASYLLGLYLAQLRGNKFADEVSSILDSLREMPEKIQQVIDAEEQIKKLGQDMSDAKSV LFLGRHVGFPVALEGALKLKEIAYLHAEGFAAGELKHGPIALVEEGQPVFVIVPSPRGRDSLHSKVVSNIQEIRARGAVT IVIAEEGDEAVNDYANFIIRIPQAPTLMQPLLSTVPLQIFACAVATAKGYNVDQPRNLAKSVTVE
Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]
COG id: COG0449
COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 SIS domains [H]
Homologues:
Organism=Homo sapiens, GI4826742, Length=688, Percent_Identity=35.1744186046512, Blast_Score=412, Evalue=1e-115, Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=35.5685131195335, Blast_Score=403, Evalue=1e-112, Organism=Homo sapiens, GI29570798, Length=198, Percent_Identity=30.8080808080808, Blast_Score=73, Evalue=1e-12, Organism=Escherichia coli, GI1790167, Length=626, Percent_Identity=45.2076677316294, Blast_Score=489, Evalue=1e-139, Organism=Escherichia coli, GI87082251, Length=328, Percent_Identity=22.2560975609756, Blast_Score=71, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17532899, Length=721, Percent_Identity=33.1484049930652, Blast_Score=383, Evalue=1e-106, Organism=Caenorhabditis elegans, GI17539970, Length=437, Percent_Identity=35.6979405034325, Blast_Score=280, Evalue=1e-75, Organism=Caenorhabditis elegans, GI17532897, Length=437, Percent_Identity=35.2402745995423, Blast_Score=276, Evalue=3e-74, Organism=Saccharomyces cerevisiae, GI6322745, Length=723, Percent_Identity=36.6528354080221, Blast_Score=392, Evalue=1e-109, Organism=Saccharomyces cerevisiae, GI6323731, Length=434, Percent_Identity=28.8018433179723, Blast_Score=182, Evalue=1e-46, Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=40.9756097560976, Blast_Score=143, Evalue=1e-34, Organism=Drosophila melanogaster, GI21357745, Length=689, Percent_Identity=33.6719883889695, Blast_Score=398, Evalue=1e-111,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000583 - InterPro: IPR017932 - InterPro: IPR005855 - InterPro: IPR001347 [H]
Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]
EC number: =2.6.1.16 [H]
Molecular weight: Translated: 67550; Mature: 67550
Theoretical pI: Translated: 4.92; Mature: 4.92
Prosite motif: PS00443 GATASE_TYPE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRMCGIVGYIGQAGDSRDYFALDVVLEGLRRLEYRGYDSAGVAVHANGEISYRKKAGKVA CCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEHHCCCCEE ALDAEIARAPLADSILAIGHTRWATHGGPTDANAHPHVVDGGKLAVVHNGIIENFAELRA EECHHHHHCCCHHHHHHHCCCEECCCCCCCCCCCCCEEECCCEEEEEECHHHHHHHHHHH ELSAKGYNFVSVTDTEVAATLLAEIYNTQANGDLTKAMQLTGQRLEGAFTLLAIHADHDD HHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCC RIVAARRNSPLVIGLGEGENFLGSDVSGFIDYTRKAVEMGNDQIVTITANDYQITNFDGS EEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCC EATGKPFDVEWDAAAAEKGGFDSFMDKEIHDQPAAVRDTLLGRLDEDGKLVLDELRIDEA CCCCCCCCCCCCCHHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEHHCCCHH TLRSVNKIIVVACGTAAYAGQVARYAIEHWCRIPTEVELAHEFRYRDPIVNEKTLVVALS HHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEC QSGETMDTLMAVRHAREQGAKVIAICNTVGSTLPREADASLYTYAGPEIAVASTKAFLAQ CCCCHHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCCCCEEEECCCCEEEHHHHHHHHH ITASYLLGLYLAQLRGNKFADEVSSILDSLREMPEKIQQVIDAEEQIKKLGQDMSDAKSV HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH LFLGRHVGFPVALEGALKLKEIAYLHAEGFAAGELKHGPIALVEEGQPVFVIVPSPRGRD HHHHHHCCCCEEECCHHHHHHHHEECCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCH SLHSKVVSNIQEIRARGAVTIVIAEEGDEAVNDYANFIIRIPQAPTLMQPLLSTVPLQIF HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH ACAVATAKGYNVDQPRNLAKSVTVE HHHHHHCCCCCCCCCHHHHHHCCCC >Mature Secondary Structure MRMCGIVGYIGQAGDSRDYFALDVVLEGLRRLEYRGYDSAGVAVHANGEISYRKKAGKVA CCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEHHCCCCEE ALDAEIARAPLADSILAIGHTRWATHGGPTDANAHPHVVDGGKLAVVHNGIIENFAELRA EECHHHHHCCCHHHHHHHCCCEECCCCCCCCCCCCCEEECCCEEEEEECHHHHHHHHHHH ELSAKGYNFVSVTDTEVAATLLAEIYNTQANGDLTKAMQLTGQRLEGAFTLLAIHADHDD HHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCC RIVAARRNSPLVIGLGEGENFLGSDVSGFIDYTRKAVEMGNDQIVTITANDYQITNFDGS EEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCC EATGKPFDVEWDAAAAEKGGFDSFMDKEIHDQPAAVRDTLLGRLDEDGKLVLDELRIDEA CCCCCCCCCCCCCHHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEHHCCCHH TLRSVNKIIVVACGTAAYAGQVARYAIEHWCRIPTEVELAHEFRYRDPIVNEKTLVVALS HHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEC QSGETMDTLMAVRHAREQGAKVIAICNTVGSTLPREADASLYTYAGPEIAVASTKAFLAQ CCCCHHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCCCCEEEECCCCEEEHHHHHHHHH ITASYLLGLYLAQLRGNKFADEVSSILDSLREMPEKIQQVIDAEEQIKKLGQDMSDAKSV HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH LFLGRHVGFPVALEGALKLKEIAYLHAEGFAAGELKHGPIALVEEGQPVFVIVPSPRGRD HHHHHHCCCCEEECCHHHHHHHHEECCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCH SLHSKVVSNIQEIRARGAVTIVIAEEGDEAVNDYANFIIRIPQAPTLMQPLLSTVPLQIF HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH ACAVATAKGYNVDQPRNLAKSVTVE HHHHHHCCCCCCCCCHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12948626 [H]