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The map label for this gene is galK [H]

Identifier: 145296191

GI number: 145296191

Start: 2330227

End: 2331522

Strand: Direct

Name: galK [H]

Synonym: cgR_2110

Alternate gene names: 145296191

Gene position: 2330227-2331522 (Clockwise)

Preceding gene: 145296189

Following gene: 145296193

Centisome position: 70.31

GC content: 57.02

Gene sequence:

>1296_bases
ATGGCCATTTGGCAGCCAACTCTCACCGGCCCGCACGGCGCACAAGTTGGATCGTCTCCCACTGAACTTCTTGAAGCCTG
CGTGGCTTTCCACCGCACTTTCTTTGACGTCAATCCCAAAGGCGCTGCTACCGCACCGGCAACATGGACGCTTATTGGTG
AGCATTCGGATTACGCCGGTGGTGTGGTGCTGGCGGCTAATGCGAATTGGCGGACTGCGGTTGCCGTCAATAAGAACCGC
GACGATGTTGTTAACGTATGCGTTGTGGATGTGGAGGGAGGCGTCGAAAAGCACTCTTTAAGCACTGCGGACATTGCAGC
TCGCGCGCACGCCCATATGAAATCCCATGATGTTTTGGGGCGGCAGACTACGCCGCCTCAGCCGGAGGGCGGCGTTGCTG
CCCGGTTGGGCGGGATTGCGTGGACAATGATCCATAAGCAAATGCTTTCGCGTGACACAAAAGGCCTGGATATCACCGTG
TTGAGCACCATTCCTGAGGGTGTGGGGCTGGGTGAAAATTCCGCCATGGATGTGGCGCTCGCATTGGCGCTGTATCGGGA
GAATATTGAGGAAGCCCCCACGAAGGCGCGCATTGCGGAGATTTGTTCGCAGTCCGCATTCATGTTCAGTGAGACTTCAG
TGTTGCGTGCGCGGCACACCGTGGCGTTGCGGGGTGAAACTGGACAGATTTCGGTGGTTGATTACGCCGATGGTTCGGTC
ACTCAGGCGCCACATCCGGTGAGTCGTTCCGCTGGTTTGTCGGCATTTGTTGTTGCTGCGCAAACTGAAACTGATCCGAG
CATTTACCGCGAGATCTATGCTCGACATGCGTTTATCGATGAAGCTGCGCGCGCTTTCAGCGTGGAATCTTTGCGGTTGC
TTCCCGACGCTTCCACTCGTGTTGTGGATTGGTTGCAGGCCGTTATTGAGGTGACTGGTCGAGAGGATCTGCCCTCGATT
GAACAAGCCCAGCGCTGGTTGAATCTGTGGGAAAACGAAACCCGGCGCGCTCAGAGGACAGCCAATGCCCTGCGTTCGAG
AAGGCTGAGTGAGTTTTCTGAGCTGCTGATGGAATCCCAAGATGATTTGAGCGACACCTTCGATTTCCCCCCTGCTGATT
TGGCGCTTGCTCGTTTGTGCGTCGAGCGGGGTGCCACAGCTGCTCGGTCCACGTCAGCGCGCGGTGTGATTGCGTTGGTT
GATGCCCATCATGCGCACAATTTTGCTGCGGATCTCAGCGAGGATGGCTTGTTGGTGGTTCCTCTCGGGCACGGGGACGT
CGCGGAACAGGGCTAG

Upstream 100 bases:

>100_bases
TAGTGTGTAGCACCCCACTATAGACCTCAATAAGAACCCGCAACGGCTAGAGTGGGTCTGTTATTTATTTGTGATTTCTA
TCTGTGGAGGCTTCTCTCAC

Downstream 100 bases:

>100_bases
CACGCCTACTTAACCAGCCTGCATGCTTAGTCAGCCGGCCACGCAAACAAAACTTCACGCTTCTTCAAGTTCGCAGTCAC
CAGTGTGACCTCTTGGTTTG

Product: galactokinase

Products: NA

Alternate protein names: Galactose kinase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MAIWQPTLTGPHGAQVGSSPTELLEACVAFHRTFFDVNPKGAATAPATWTLIGEHSDYAGGVVLAANANWRTAVAVNKNR
DDVVNVCVVDVEGGVEKHSLSTADIAARAHAHMKSHDVLGRQTTPPQPEGGVAARLGGIAWTMIHKQMLSRDTKGLDITV
LSTIPEGVGLGENSAMDVALALALYRENIEEAPTKARIAEICSQSAFMFSETSVLRARHTVALRGETGQISVVDYADGSV
TQAPHPVSRSAGLSAFVVAAQTETDPSIYREIYARHAFIDEAARAFSVESLRLLPDASTRVVDWLQAVIEVTGREDLPSI
EQAQRWLNLWENETRRAQRTANALRSRRLSEFSELLMESQDDLSDTFDFPPADLALARLCVERGATAARSTSARGVIALV
DAHHAHNFAADLSEDGLLVVPLGHGDVAEQG

Sequences:

>Translated_431_residues
MAIWQPTLTGPHGAQVGSSPTELLEACVAFHRTFFDVNPKGAATAPATWTLIGEHSDYAGGVVLAANANWRTAVAVNKNR
DDVVNVCVVDVEGGVEKHSLSTADIAARAHAHMKSHDVLGRQTTPPQPEGGVAARLGGIAWTMIHKQMLSRDTKGLDITV
LSTIPEGVGLGENSAMDVALALALYRENIEEAPTKARIAEICSQSAFMFSETSVLRARHTVALRGETGQISVVDYADGSV
TQAPHPVSRSAGLSAFVVAAQTETDPSIYREIYARHAFIDEAARAFSVESLRLLPDASTRVVDWLQAVIEVTGREDLPSI
EQAQRWLNLWENETRRAQRTANALRSRRLSEFSELLMESQDDLSDTFDFPPADLALARLCVERGATAARSTSARGVIALV
DAHHAHNFAADLSEDGLLVVPLGHGDVAEQG
>Mature_430_residues
AIWQPTLTGPHGAQVGSSPTELLEACVAFHRTFFDVNPKGAATAPATWTLIGEHSDYAGGVVLAANANWRTAVAVNKNRD
DVVNVCVVDVEGGVEKHSLSTADIAARAHAHMKSHDVLGRQTTPPQPEGGVAARLGGIAWTMIHKQMLSRDTKGLDITVL
STIPEGVGLGENSAMDVALALALYRENIEEAPTKARIAEICSQSAFMFSETSVLRARHTVALRGETGQISVVDYADGSVT
QAPHPVSRSAGLSAFVVAAQTETDPSIYREIYARHAFIDEAARAFSVESLRLLPDASTRVVDWLQAVIEVTGREDLPSIE
QAQRWLNLWENETRRAQRTANALRSRRLSEFSELLMESQDDLSDTFDFPPADLALARLCVERGATAARSTSARGVIALVD
AHHAHNFAADLSEDGLLVVPLGHGDVAEQG

Specific function: Galactose metabolism; first step. [C]

COG id: COG0153

COG function: function code G; Galactokinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. GalK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000705
- InterPro:   IPR022963
- InterPro:   IPR019741
- InterPro:   IPR019539
- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR006203
- InterPro:   IPR006206
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF10509 GalKase_gal_bdg; PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.6 [H]

Molecular weight: Translated: 46334; Mature: 46203

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIWQPTLTGPHGAQVGSSPTELLEACVAFHRTFFDVNPKGAATAPATWTLIGEHSDYAG
CCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCC
GVVLAANANWRTAVAVNKNRDDVVNVCVVDVEGGVEKHSLSTADIAARAHAHMKSHDVLG
CEEEEECCCCEEEEEECCCCCCEEEEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHCCC
RQTTPPQPEGGVAARLGGIAWTMIHKQMLSRDTKGLDITVLSTIPEGVGLGENSAMDVAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
ALALYRENIEEAPTKARIAEICSQSAFMFSETSVLRARHTVALRGETGQISVVDYADGSV
HHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCC
TQAPHPVSRSAGLSAFVVAAQTETDPSIYREIYARHAFIDEAARAFSVESLRLLPDASTR
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCHHH
VVDWLQAVIEVTGREDLPSIEQAQRWLNLWENETRRAQRTANALRSRRLSEFSELLMESQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDLSDTFDFPPADLALARLCVERGATAARSTSARGVIALVDAHHAHNFAADLSEDGLLVV
CCHHHHCCCCCHHHHHHHHHHHHCCCHHCCCCCCCEEEEEECHHHHHHHHCCCCCCEEEE
PLGHGDVAEQG
ECCCCCCCCCC
>Mature Secondary Structure 
AIWQPTLTGPHGAQVGSSPTELLEACVAFHRTFFDVNPKGAATAPATWTLIGEHSDYAG
CEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCC
GVVLAANANWRTAVAVNKNRDDVVNVCVVDVEGGVEKHSLSTADIAARAHAHMKSHDVLG
CEEEEECCCCEEEEEECCCCCCEEEEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHCCC
RQTTPPQPEGGVAARLGGIAWTMIHKQMLSRDTKGLDITVLSTIPEGVGLGENSAMDVAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
ALALYRENIEEAPTKARIAEICSQSAFMFSETSVLRARHTVALRGETGQISVVDYADGSV
HHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCC
TQAPHPVSRSAGLSAFVVAAQTETDPSIYREIYARHAFIDEAARAFSVESLRLLPDASTR
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCHHH
VVDWLQAVIEVTGREDLPSIEQAQRWLNLWENETRRAQRTANALRSRRLSEFSELLMESQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDLSDTFDFPPADLALARLCVERGATAARSTSARGVIALVDAHHAHNFAADLSEDGLLVV
CCHHHHCCCCCHHHHHHHHHHHHCCCHHCCCCCCCEEEEEECHHHHHHHHCCCCCCEEEE
PLGHGDVAEQG
ECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]