Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 145296123

GI number: 145296123

Start: 2250851

End: 2251951

Strand: Reverse

Name: mraY

Synonym: cgR_2043

Alternate gene names: 145296123

Gene position: 2251951-2250851 (Counterclockwise)

Preceding gene: 145296124

Following gene: 145296122

Centisome position: 67.95

GC content: 52.95

Gene sequence:

>1101_bases
ATGCAACAGATTATGGTCAGTGGAACGGTTGCGTTCCTCGTCTCAATCTTTCTCACCCCGGTGTTGATCCGTTATTTCAC
TAACCGCCAGTTGGGCCAGGAAATCCGTGAAGAAGGCCTGCAGTCTCACTTGCGTAAGCGTGGCACTCCAACCATGGGTG
GCATTGCGATTATCGCGGGCATTGTTGTGGCCTATGTGTTTACCAATATCTTGGCCATGATCCAAGGCGTTGGTGGATTC
ACAGTCTCCGGCTTGCTCGTGTTGGGTCTGACCTTGGGCCTTGGTGCCACTGGTTTCGCCGATGACTTCATCAAGCTGTA
CATGAACCGAAACCTTGGTTTGAACAAGACCGCTAAGCTGGTGTCTCAGCTGGCCATTGCGTTGATCTTTGGTTTTTTGG
TACTGCAGTTTCCCGATGAAAACGGTCTGACCCCAGCATCAACCCACCTGTCATTCATTCGCGATATCGACACCATTGAC
CTTGGCTTCGGGGGCAGCGTTTTTGGCATCATCGTGTTCCTCATTTTTATCTACGTTGTGGTCAGCGCGTGGTCGAATGC
CGTGAACATCACTGATGGTTTGGATGGTTTGGCTGCAGGTACCACAGCATTTGTCATGGGTGCTTACACCTTGATCACGT
TCTGGCAGTTCCGAAACTCCTGCGATACTGCAGTGGAAGCGGGTTGCTATACGGTGCGTGATCCACTGGATTTGTCTGTG
TTGTGTGCTGCTGGTCTGGGCGCCACCTTGGGCTTTCTGTGGTGGAATGCGGCGCCGGCAAAGATCTTCATGGGCGATAC
TGGTTCTTTGGCACTGGGCGGTTTGGTTGCAGGTATTTCTGTGGTTAGCCGCACCGAGCTGCTCATGGTTATCATCGGCG
CGCTGTTTGTCATTGAGATCGCTTCTGTTGCGATCCAGATCGGCGTGTTTAAGACCCGCGGTAAGCGTGTGTTCAAAATG
GCTCCTATCCACCACCACTTCGAGGCCCTTGGGTGGGCTGAAACTACCGTGGCCATCCGTTTCTGGCTGATCGCGATCAT
GGCTGTGTTGGCGGGTGTCGGTGTGTTTTACAGCGACTGGCTCCACTTAGCGGAGGTATAA

Upstream 100 bases:

>100_bases
GGTCGCAGAAGCACTACATGGCATGGTGCCGGGCCTCAAAAACACAGGTAGCTCGGTCAACGACGATTCTCGTCGGAACG
TGGAAGGACAGTAGAAAACA

Downstream 100 bases:

>100_bases
ATAATTATGGTTTCTCTGTCCCATTTACCTCAGGCGCTGCAGGGCCGTATTCTTGTGGCCGGCGCTGGTGTTTCCGGCCT
GTCCATTGCAAAGATGCTCA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGF
TVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTID
LGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKM
APIHHHFEALGWAETTVAIRFWLIAIMAVLAGVGVFYSDWLHLAEV

Sequences:

>Translated_366_residues
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGF
TVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTID
LGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKM
APIHHHFEALGWAETTVAIRFWLIAIMAVLAGVGVFYSDWLHLAEV
>Mature_366_residues
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGF
TVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTID
LGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKM
APIHHHFEALGWAETTVAIRFWLIAIMAVLAGVGVFYSDWLHLAEV

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=351, Percent_Identity=39.6011396011396, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CORGB (A4QFM6)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138944.1
- STRING:   A4QFM6
- GeneID:   4993165
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2043
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39239; Mature: 39239

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1deed2b0)-; HASH(0x1deed37c)-; HASH(0x1e1186d4)-; HASH(0x1dfeff4c)-; HASH(0x1de181ac)-; HASH(0x1e08b4dc)-; HASH(0x1dff0e18)-; HASH(0x1e09d1fc)-; HASH(0x1dbb22f0)-; HASH(0x1df8a2a0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAG
CCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IVVAYVFTNILAMIQGVGGFTVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHH
VSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTIDLGFGGSVFGIIVFLIFIYVV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHH
VSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHH
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEI
HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVAIQIGVFKTRGKRVFKMAPIHHHFEALGWAETTVAIRFWLIAIMAVLAGVGVFYSDW
HHHHHHHHHEECCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHLAEV
HHHHCH
>Mature Secondary Structure
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAG
CCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IVVAYVFTNILAMIQGVGGFTVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHH
VSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTIDLGFGGSVFGIIVFLIFIYVV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHH
VSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHH
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEI
HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVAIQIGVFKTRGKRVFKMAPIHHHFEALGWAETTVAIRFWLIAIMAVLAGVGVFYSDW
HHHHHHHHHEECCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHLAEV
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA