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The map label for this gene is agaR [H]

Identifier: 145295836

GI number: 145295836

Start: 1956894

End: 1957673

Strand: Direct

Name: agaR [H]

Synonym: cgR_1761

Alternate gene names: 145295836

Gene position: 1956894-1957673 (Clockwise)

Preceding gene: 145295835

Following gene: 145295837

Centisome position: 59.05

GC content: 55.38

Gene sequence:

>780_bases
ATGTACGCAGAGGAGCGCCGTCGACAGATTGCCTCATTAACGGCAGTTGAGGGACGTGTAAATGTCACAGAATTAGCGGG
CCGATTCGATGTCACTGCAGAGACGATTCGACGAGACCTTGCGGTGCTAGACCGCGAGGGAATTGTTCACCGCGTTCACG
GTGGCGCAGTAGCCACCCAATCTTTCCAAACCACAGAGTTGAGCTTGGATACTCGTTTCAGGTCTGCATCGTCAGCAAAG
TACTCCATTGCCAAGGCAGCGATGCAGTTCCTGCCCGCTGAGCATGGCGGACTGTTCCTCGATGCGGGAACTACTGTTAC
TGCTTTGGCCGATCTCATTTCTGAGCATCCTAGCGCCAAGCAGTGGTCGATCGTGACCAACTGCCTCCCCATCGCACTTA
ATCTGGCCAACGCCGGGCTTGATGATGTCCAGCTGCTTGGAGGAAGCGTTCGCGCGATCACCCAGGCTGTTGTGGGTGAC
ACTGCGCTTCGTACTCTCGCGCTGATGCGTGCGGATGTAGTGTTCATCGGCACCAACGCGTTGACGTTGGATCACGGATT
GTCTACGGCCGATTCCCAAGAGGCTGCCATGAAATCTGCGATGATCACCAACGCCCACAAGGTGGTGGTGTTGTGTGACT
CCACCAAGATGGGCACCGACTACCTCGTGAGCTTTGGCGCAATCAGCGATATCGATGTGGTGGTCACCGATGCGGGTGCA
CCAGCAAGTTTCGTTGAGCAGTTGCGAGAACGCGATGTAGAAGTTGTGATTGCAGAATGA

Upstream 100 bases:

>100_bases
CGCCGGCAACCAAATGAGGCTTTTGGGCGTTGGACAGTGAGACAATGGGTAAGAAATTCGGACATATTTAGTAAATTGGC
TTTTTGCTTTAAGGAGTGAC

Downstream 100 bases:

>100_bases
TTCTTACAGTCACTGCAAGTCCGTATCTGTTGAGCACCAATGAGCTTGACGGCACCATCGAAATTGGCGAAGCAAACAAA
ATCCGGCAGGTTTCCACTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MYAEERRRQIASLTAVEGRVNVTELAGRFDVTAETIRRDLAVLDREGIVHRVHGGAVATQSFQTTELSLDTRFRSASSAK
YSIAKAAMQFLPAEHGGLFLDAGTTVTALADLISEHPSAKQWSIVTNCLPIALNLANAGLDDVQLLGGSVRAITQAVVGD
TALRTLALMRADVVFIGTNALTLDHGLSTADSQEAAMKSAMITNAHKVVVLCDSTKMGTDYLVSFGAISDIDVVVTDAGA
PASFVEQLRERDVEVVIAE

Sequences:

>Translated_259_residues
MYAEERRRQIASLTAVEGRVNVTELAGRFDVTAETIRRDLAVLDREGIVHRVHGGAVATQSFQTTELSLDTRFRSASSAK
YSIAKAAMQFLPAEHGGLFLDAGTTVTALADLISEHPSAKQWSIVTNCLPIALNLANAGLDDVQLLGGSVRAITQAVVGD
TALRTLALMRADVVFIGTNALTLDHGLSTADSQEAAMKSAMITNAHKVVVLCDSTKMGTDYLVSFGAISDIDVVVTDAGA
PASFVEQLRERDVEVVIAE
>Mature_259_residues
MYAEERRRQIASLTAVEGRVNVTELAGRFDVTAETIRRDLAVLDREGIVHRVHGGAVATQSFQTTELSLDTRFRSASSAK
YSIAKAAMQFLPAEHGGLFLDAGTTVTALADLISEHPSAKQWSIVTNCLPIALNLANAGLDDVQLLGGSVRAITQAVVGD
TALRTLALMRADVVFIGTNALTLDHGLSTADSQEAAMKSAMITNAHKVVVLCDSTKMGTDYLVSFGAISDIDVVVTDAGA
PASFVEQLRERDVEVVIAE

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=258, Percent_Identity=34.1085271317829, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=28.740157480315, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789829, Length=255, Percent_Identity=30.5882352941176, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789059, Length=261, Percent_Identity=31.0344827586207, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788069, Length=256, Percent_Identity=26.953125, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI226510968, Length=259, Percent_Identity=30.1158301158301, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787540, Length=239, Percent_Identity=28.0334728033473, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790635, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27543; Mature: 27543

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS51000 HTH_DEOR_2 ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAEERRRQIASLTAVEGRVNVTELAGRFDVTAETIRRDLAVLDREGIVHRVHGGAVATQ
CCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEC
SFQTTELSLDTRFRSASSAKYSIAKAAMQFLPAEHGGLFLDAGTTVTALADLISEHPSAK
CCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCC
QWSIVTNCLPIALNLANAGLDDVQLLGGSVRAITQAVVGDTALRTLALMRADVVFIGTNA
CHHHHHHHHHHEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCE
LTLDHGLSTADSQEAAMKSAMITNAHKVVVLCDSTKMGTDYLVSFGAISDIDVVVTDAGA
EEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHEECCCCCCCEEEEECCCC
PASFVEQLRERDVEVVIAE
CHHHHHHHHHCCEEEEEEC
>Mature Secondary Structure
MYAEERRRQIASLTAVEGRVNVTELAGRFDVTAETIRRDLAVLDREGIVHRVHGGAVATQ
CCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEC
SFQTTELSLDTRFRSASSAKYSIAKAAMQFLPAEHGGLFLDAGTTVTALADLISEHPSAK
CCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCC
QWSIVTNCLPIALNLANAGLDDVQLLGGSVRAITQAVVGDTALRTLALMRADVVFIGTNA
CHHHHHHHHHHEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCE
LTLDHGLSTADSQEAAMKSAMITNAHKVVVLCDSTKMGTDYLVSFGAISDIDVVVTDAGA
EEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHEECCCCCCCEEEEECCCC
PASFVEQLRERDVEVVIAE
CHHHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]