| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is coaBC [H]
Identifier: 145295726
GI number: 145295726
Start: 1838666
End: 1839928
Strand: Reverse
Name: coaBC [H]
Synonym: cgR_1653
Alternate gene names: 145295726
Gene position: 1839928-1838666 (Counterclockwise)
Preceding gene: 145295727
Following gene: 145295725
Centisome position: 55.52
GC content: 56.37
Gene sequence:
>1263_bases ATGACTCATGTTTCAAGCCTCTCCGCACCCCGCAACGTGGTTGTTGGTGTTGCCGGTGGAATCGCAGCGTACAAGGCGTG TCACATCGTGCGCGCGTTTAAAGAAGCGGGCGATAATGTGCGCGTGGTTCCTACGGAATCCGCGTTGAAGTTTGTGGGGA AGGCGACGTTTGAAGCGTTGTCTGGCAATCTGGTGTCTACAACGGTGTTTGATGCGGTGGATTCGGTGCAGCATGTGAAA GTTGGCCAGGAGGCTGATTTGATCGTGATTGCGCCGGCGACAGCCGATTTGATGGCGCGTGTGGTGGCAGGTCGCGGTGA CGATCTGTTGGCGGCGACGCTGCTGGTGGCAACGTGCCCCGTGGTTATCGCGCCGGCCATGCATACGGAGATGTGGTTTA ATCCGGCTACCGTAGCCAATGTGGCAACGCTGAGGCAGCGGGGGATTACCGTGATTGAGCCTGCGCATGGTCGACTCACC GGTAAAGATACAGGCCCTGGCCGGCTGCCGGATCCAGAGCAGATTGTTGATTTAGCCAATGCGATGCACGCCGGGGCGAG GTTGCCTCAGGATTTGGCGGGCAAGAAAGTGCTGATCACTGCTGGTGGCACGCATGAGCATATTGATCCTGTGCGCTTTA TTGGCAATAGTTCCTCGGGCCGTCAAGGTTTTGCGTTGGGTGAAATCGCAGCGCAACGAGGCGCACATGTCACCATCGTG GCGGGAAATACTGCGGAGCTGTCCACTCCAGCAGGCGCAGAGATCGTGCCGGTGGTGTCCACACAAGACATGTTTGATGC AGTCCAGGAACGAGCTGGCCAATCTGATTTCATCGTCATGGCGGCAGCGGTAGCTGATTTCACGCCCGCATCGCAGGCGA CATCGAAGTTGAAGAAGGGCTCAGATTCTGATGAAGACGCATTGAGCACCATCTCGTTGGTGGAAAACCCGGATATTTTG GCTACCACGGTGAAGCGTCGTGAAGCAGGAGAGCTGGACAGTAATCCTGTCATCGTGGGTTTTGCTGCGGAAACTGGCGA CGAGCACACCACCGCCTTGGAGTATGCGCGCAAGAAACTGCAGAAGAAGGGCTGCGACCTCCTCATGTGTAATGAGGTGG GCATGGGCAAAGTGTTTGGACAAAAGCACAATGAGGGCTGGATTTTGGATGCTCACGGTGGGGTAGTCAATGTGGAGCAC GGCAGCAAAATCGATGTTGCTGCGCAAATTTGGGACGTGGCACTGGCGTATCGCGAAGTCTAG
Upstream 100 bases:
>100_bases ACAGCGGAGGTCGAGGGAGAGCGTGGGGTGGCGTCGAAAAGCATCTTGTAGAGTGTGTGGGAACCCAGCCAGCCTCTTAC TTTGAAGGATTGTTGTGCCC
Downstream 100 bases:
>100_bases AAAAATCCAGCTAGACCACTGACATTGCAGTTTTAGACAGCTTGGTCTATATTGGTTTTTTGTATTTAAGACTATTTATT CTCAACTTCTTCGAAAGAAG
Product: bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase
Products: NA
Alternate protein names: DNA/pantothenate metabolism flavoprotein; Phosphopantothenoylcysteine decarboxylase; PPCDC; CoaC; Phosphopantothenate--cysteine ligase; CoaB; PPC synthetase; PPCS; Phosphopantothenoylcysteine synthase [H]
Number of amino acids: Translated: 420; Mature: 419
Protein sequence:
>420_residues MTHVSSLSAPRNVVVGVAGGIAAYKACHIVRAFKEAGDNVRVVPTESALKFVGKATFEALSGNLVSTTVFDAVDSVQHVK VGQEADLIVIAPATADLMARVVAGRGDDLLAATLLVATCPVVIAPAMHTEMWFNPATVANVATLRQRGITVIEPAHGRLT GKDTGPGRLPDPEQIVDLANAMHAGARLPQDLAGKKVLITAGGTHEHIDPVRFIGNSSSGRQGFALGEIAAQRGAHVTIV AGNTAELSTPAGAEIVPVVSTQDMFDAVQERAGQSDFIVMAAAVADFTPASQATSKLKKGSDSDEDALSTISLVENPDIL ATTVKRREAGELDSNPVIVGFAAETGDEHTTALEYARKKLQKKGCDLLMCNEVGMGKVFGQKHNEGWILDAHGGVVNVEH GSKIDVAAQIWDVALAYREV
Sequences:
>Translated_420_residues MTHVSSLSAPRNVVVGVAGGIAAYKACHIVRAFKEAGDNVRVVPTESALKFVGKATFEALSGNLVSTTVFDAVDSVQHVK VGQEADLIVIAPATADLMARVVAGRGDDLLAATLLVATCPVVIAPAMHTEMWFNPATVANVATLRQRGITVIEPAHGRLT GKDTGPGRLPDPEQIVDLANAMHAGARLPQDLAGKKVLITAGGTHEHIDPVRFIGNSSSGRQGFALGEIAAQRGAHVTIV AGNTAELSTPAGAEIVPVVSTQDMFDAVQERAGQSDFIVMAAAVADFTPASQATSKLKKGSDSDEDALSTISLVENPDIL ATTVKRREAGELDSNPVIVGFAAETGDEHTTALEYARKKLQKKGCDLLMCNEVGMGKVFGQKHNEGWILDAHGGVVNVEH GSKIDVAAQIWDVALAYREV >Mature_419_residues THVSSLSAPRNVVVGVAGGIAAYKACHIVRAFKEAGDNVRVVPTESALKFVGKATFEALSGNLVSTTVFDAVDSVQHVKV GQEADLIVIAPATADLMARVVAGRGDDLLAATLLVATCPVVIAPAMHTEMWFNPATVANVATLRQRGITVIEPAHGRLTG KDTGPGRLPDPEQIVDLANAMHAGARLPQDLAGKKVLITAGGTHEHIDPVRFIGNSSSGRQGFALGEIAAQRGAHVTIVA GNTAELSTPAGAEIVPVVSTQDMFDAVQERAGQSDFIVMAAAVADFTPASQATSKLKKGSDSDEDALSTISLVENPDILA TTVKRREAGELDSNPVIVGFAAETGDEHTTALEYARKKLQKKGCDLLMCNEVGMGKVFGQKHNEGWILDAHGGVVNVEHG SKIDVAAQIWDVALAYREV
Specific function: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine [H]
COG id: COG0452
COG function: function code H; Phosphopantothenoylcysteine synthetase/decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the PPC synthetase family [H]
Homologues:
Organism=Escherichia coli, GI87082301, Length=365, Percent_Identity=40.8219178082192, Blast_Score=232, Evalue=3e-62,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005252 - InterPro: IPR007085 - InterPro: IPR003382 [H]
Pfam domain/function: PF04127 DFP; PF02441 Flavoprotein [H]
EC number: =4.1.1.36; =6.3.2.5 [H]
Molecular weight: Translated: 43967; Mature: 43836
Theoretical pI: Translated: 5.73; Mature: 5.73
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTHVSSLSAPRNVVVGVAGGIAAYKACHIVRAFKEAGDNVRVVPTESALKFVGKATFEAL CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH SGNLVSTTVFDAVDSVQHVKVGQEADLIVIAPATADLMARVVAGRGDDLLAATLLVATCP CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHH VVIAPAMHTEMWFNPATVANVATLRQRGITVIEPAHGRLTGKDTGPGRLPDPEQIVDLAN HHEECCHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHH AMHAGARLPQDLAGKKVLITAGGTHEHIDPVRFIGNSSSGRQGFALGEIAAQRGAHVTIV HHHHCCCCCHHHCCCEEEEEECCCCCCCCHHEEECCCCCCCCCCCHHHHHHHCCCEEEEE AGNTAELSTPAGAEIVPVVSTQDMFDAVQERAGQSDFIVMAAAVADFTPASQATSKLKKG ECCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEHHHCCCCHHHHHHHHHCC SDSDEDALSTISLVENPDILATTVKRREAGELDSNPVIVGFAAETGDEHTTALEYARKKL CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH QKKGCDLLMCNEVGMGKVFGQKHNEGWILDAHGGVVNVEHGSKIDVAAQIWDVALAYREV HHCCCCEEEECCCCCCHHHCCCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHCC >Mature Secondary Structure THVSSLSAPRNVVVGVAGGIAAYKACHIVRAFKEAGDNVRVVPTESALKFVGKATFEAL CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH SGNLVSTTVFDAVDSVQHVKVGQEADLIVIAPATADLMARVVAGRGDDLLAATLLVATCP CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHH VVIAPAMHTEMWFNPATVANVATLRQRGITVIEPAHGRLTGKDTGPGRLPDPEQIVDLAN HHEECCHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHH AMHAGARLPQDLAGKKVLITAGGTHEHIDPVRFIGNSSSGRQGFALGEIAAQRGAHVTIV HHHHCCCCCHHHCCCEEEEEECCCCCCCCHHEEECCCCCCCCCCCHHHHHHHCCCEEEEE AGNTAELSTPAGAEIVPVVSTQDMFDAVQERAGQSDFIVMAAAVADFTPASQATSKLKKG ECCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEHHHCCCCHHHHHHHHHCC SDSDEDALSTISLVENPDILATTVKRREAGELDSNPVIVGFAAETGDEHTTALEYARKKL CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH QKKGCDLLMCNEVGMGKVFGQKHNEGWILDAHGGVVNVEHGSKIDVAAQIWDVALAYREV HHCCCCEEEECCCCCCHHHCCCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]