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The map label for this gene is uppP

Identifier: 145295648

GI number: 145295648

Start: 1742215

End: 1743096

Strand: Reverse

Name: uppP

Synonym: cgR_1575

Alternate gene names: 145295648

Gene position: 1743096-1742215 (Counterclockwise)

Preceding gene: 145295652

Following gene: 145295647

Centisome position: 52.6

GC content: 54.88

Gene sequence:

>882_bases
GTGAATGAAGAGATAACCCTCCTAGCCGCAGCAGCAGATCCTGCCGCAACTGAAAATATTGGCTGGGTACAAACCATTGT
GCTCTCCATCGTTCAAGGCCTCACAGAGTTCCTGCCGATCAGCTCCAGCGGACACCTCCGAATCATCTCTGAGCTGTTCT
GGGGTGCCGATGCCGGCGCGTCCTTTACCGCCGTGGTTCAGCTTGGTACCGAAGCCGCAGTGCTGGTGTTTTTTGCCAAG
GAAATCTGGCAAATCATCACAGGTTGGTTCGCTGGCGTATTCAATAAGGAACGCCGCGGATTTGAATACCGCATGGGCTG
GATGATCATTGTTGCCACCATTCCCGTCGTGATCTTGGGTGTGTTGGGCAAGGACCTGATCCGTGAGGCGCTGCGAAATA
TGTGGATCACTGCATCCGTGCTGATCCTGTTCTCCCTGGTGTTCATTTTGGCCGAGAAGATGGGCAAGAAGGAACGCGAC
TACGACAAGCTGACCATGAAAGATGCCATCATCATGGGTCTTGCACAGTGTCTTGCGCTGATCCCTGGCGTGTCTCGCTC
CGGCGGCACCATCTCTGCTGGTTTGTTCCTTGGTCTCAAGCGAGAAGTAGCCACCAAGTTCTCCTTCCTGCTGGCAATCC
CTGCAGTGCTTGGCTCCGGTTTGTACTCCCTGCCTGACGCTTTTGCGCCAAGCTCCGGACAAGCTGCCTCCGGCCTACAG
CTCACCGTGGGTACCCTGTTTGCCTTCGTAGTTGGCTATATTTCCATTGCGTGGCTGATGAAGTTCGTGGCAAACCACTC
CTTCAGCTGGTTTGCTGCATACCGTATTCCTGCAGGTCTGCTCGTGATGCTGCTGCTCGCACTGGGCATGCTCAACCCAT
AA

Upstream 100 bases:

>100_bases
GCCCAAACCGAGCCTGGATACCCGCAAACCACTTGAACCGACCATTCGCTGTTTCACGCCCACCACACTACTGAGGATGC
AAAGTAGTACGGTAGATCGG

Downstream 100 bases:

>100_bases
AATTTCTGTACATCTTAAAAATCCGCCGCATTCGTGTTGGCGGATTTTTGGTTTGTGGAATAGGTGCACTGGCGGCTTGG
TTGAAGTTTTAGGTGACATT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNEEITLLAAAADPAATENIGWVQTIVLSIVQGLTEFLPISSSGHLRIISELFWGADAGASFTAVVQLGTEAAVLVFFAK
EIWQIITGWFAGVFNKERRGFEYRMGWMIIVATIPVVILGVLGKDLIREALRNMWITASVLILFSLVFILAEKMGKKERD
YDKLTMKDAIIMGLAQCLALIPGVSRSGGTISAGLFLGLKREVATKFSFLLAIPAVLGSGLYSLPDAFAPSSGQAASGLQ
LTVGTLFAFVVGYISIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLALGMLNP

Sequences:

>Translated_293_residues
MNEEITLLAAAADPAATENIGWVQTIVLSIVQGLTEFLPISSSGHLRIISELFWGADAGASFTAVVQLGTEAAVLVFFAK
EIWQIITGWFAGVFNKERRGFEYRMGWMIIVATIPVVILGVLGKDLIREALRNMWITASVLILFSLVFILAEKMGKKERD
YDKLTMKDAIIMGLAQCLALIPGVSRSGGTISAGLFLGLKREVATKFSFLLAIPAVLGSGLYSLPDAFAPSSGQAASGLQ
LTVGTLFAFVVGYISIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLALGMLNP
>Mature_293_residues
MNEEITLLAAAADPAATENIGWVQTIVLSIVQGLTEFLPISSSGHLRIISELFWGADAGASFTAVVQLGTEAAVLVFFAK
EIWQIITGWFAGVFNKERRGFEYRMGWMIIVATIPVVILGVLGKDLIREALRNMWITASVLILFSLVFILAEKMGKKERD
YDKLTMKDAIIMGLAQCLALIPGVSRSGGTISAGLFLGLKREVATKFSFLLAIPAVLGSGLYSLPDAFAPSSGQAASGLQ
LTVGTLFAFVVGYISIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLALGMLNP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=254, Percent_Identity=36.6141732283465, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_CORGB (A4QEA1)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138469.1
- STRING:   A4QEA1
- GeneID:   4992977
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1575
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   FKAWIAS
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31627; Mature: 31627

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ca8ca6c)-; HASH(0x1c46c7b0)-; HASH(0x1b955eec)-; HASH(0x1d074c98)-; HASH(0x1d6a6768)-; HASH(0x1c25351c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEEITLLAAAADPAATENIGWVQTIVLSIVQGLTEFLPISSSGHLRIISELFWGADAGA
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCC
SFTAVVQLGTEAAVLVFFAKEIWQIITGWFAGVFNKERRGFEYRMGWMIIVATIPVVILG
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLGKDLIREALRNMWITASVLILFSLVFILAEKMGKKERDYDKLTMKDAIIMGLAQCLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IPGVSRSGGTISAGLFLGLKREVATKFSFLLAIPAVLGSGLYSLPDAFAPSSGQAASGLQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHH
LTVGTLFAFVVGYISIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLALGMLNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MNEEITLLAAAADPAATENIGWVQTIVLSIVQGLTEFLPISSSGHLRIISELFWGADAGA
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCC
SFTAVVQLGTEAAVLVFFAKEIWQIITGWFAGVFNKERRGFEYRMGWMIIVATIPVVILG
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLGKDLIREALRNMWITASVLILFSLVFILAEKMGKKERDYDKLTMKDAIIMGLAQCLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IPGVSRSGGTISAGLFLGLKREVATKFSFLLAIPAVLGSGLYSLPDAFAPSSGQAASGLQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHH
LTVGTLFAFVVGYISIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLALGMLNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA