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The map label for this gene is secA2

Identifier: 145295573

GI number: 145295573

Start: 1661516

End: 1663807

Strand: Direct

Name: secA2

Synonym: cgR_1500

Alternate gene names: 145295573

Gene position: 1661516-1663807 (Clockwise)

Preceding gene: 145295568

Following gene: 145295574

Centisome position: 50.13

GC content: 57.98

Gene sequence:

>2292_bases
GTGGCCGGTTTTGATTGGTTTTGGAAGGCCCTTGGCGGCAAATCGGGCAGAAACCAAAAACGTAGCGTGGCAATTGTCAA
TCAGGCAGAAAACCATGTAGCGGAATTAGACGCGCTGGATGATGTTGCATTGGCGCAGCGTGCCAAGGATCTAGCCAGTG
GTGGACGCATTGACAATCATGCGGAATTCCTCGCCATTTTGGGTGTGGCATCGCAGCGGACATTGGGGCTGAAGCCGTAT
CCGGCGCAATCACAGGCGGTGTTGCGTCTCATTGAAGGCGATGTGGTGCACATGGCTACCGGTGAGGGCAAGACTTTGGT
GGGCGCGATGGCGGCCACCGGTCTGGGGTTGATGGGCAAGCGAGTCCATTCGATTACCGTCAATGATTATTTGGCGGTGC
GCGATGCCGAATGGATGCGGCCATTGGTCGAATTTTTCGGTCTGAGCGTGGCGAGCATCAGCGAGAAGATGGATGCAGGG
GAGCGTCGACAAGCATATAAAGCCGCAATTGTCTACGGACCTGTCAATGAAATCGGCTTTGACGTGCTGCGTGATCAGCT
AATTACCCGGCGCGAAGACGCCGTGCAGCATGGCGCCGACGTCGCGATTATCGATGAGGCCGATTCCGTGCTTGTCGACG
AGGCCCTGGTGCCACTCGTCCTCGCCGGCAACCAGCCCGGCCATGCGCCGCGCGGCAAAATCACCGATGTGGTGCGCTCG
CTGAAAGAAAACGACGATTACACCATCGACGATGATCGTCGCAACGTCTTCCTCACCGACAAGGGTGCCGCCAAATTAGA
GCAGCAGCTGGGCATCAGCAGCCTCTACGACGATGAGCACGTCGGCTCGACGCTCGTGCAGGTCAACCTCGCCCTCCACG
CGCAGGCACTGCTCATCCGCGACATCCACTACATCGTCCGCGACAGCAAGGTCTTGCTTATCGACGCCTCCCGCGGCCGT
GTCGCCGACCTGCAGCGCTGGCCCGACGGCCTGCAAGCAGCAGTGGAGGCCAAGGAAGGTCTCGCGGTTTCTGAAGGCGG
CAAGATCCTTGACACCATCACACTTCAGGCGTTGATTGGTCGCTACCCAATGGCATGCGGCATGACAGGTACCGCCGTGG
AGGCAACCAATCAGCTACGCACCTTCTATGACTTGCATGTTTCTGTCATTGAGCGCAATCATCCGCTGAAGCGCTTTGAT
GAAGCTGACCGTATCTACGCCACCATGGCGGAGAAAAACCGCGCCATCATCGATGAAATCGCACTCCTTCACAGCACGGG
GCAGCCAGTCCTGGTGGGTACCCACGATGTGGCAGAGTCGGAAGAACTCGCCACTGCACTGCGTGAACTCAACATCGAAG
TAAGCGTTCTCAACGCCAAGAATGATGCCGAAGAAGCCCAGATCATCGCAGAGGCTGGCGATATTGGACGAGTGACCGTT
TCCACTCAGATGGCCGGCCGCGGTACCGATATTCGCCTCGGTGGCGCCGATGAAGCCGACTACGATGAAGTGGTGAAACT
CGGTGGACTCGCCGTTATCGGCACCGCCCGCCACCGTTCTCAGCGCCTGGACAACCAGCTGCGCGGACGTGCGGGACGAC
AAGGAGATCCAGGCCTGAGCCTTTTCTTTGTCTCCCTCGATGATGATGTGGTGGTCTCAGGCGGGTCAGGGGAGAGCGTG
AGTGCGCAACCCGATGCCACCGGGCTGATTGACTCAGATCGCATCCGCGATTGGGTCGGACACTGCCAGCGCGTCACCGA
AGGACAGCTGCTGGAAATCCACTCCCAGAGCTGGAATTACAACAAGCTCCTTGCCGATCAACGCGTGATCATTGACGAGC
GCCGCGAACGCCTCCTCGACACCGCCTTAGCGTGGGAGGAACTGGCACAGCATGCACCAGCGCGGGCTGCAGAGCTTGAA
GACCTTGATCAGTCCGTGAGGGAACAGGCAGGACGAGACATCATGCTGTACCACCTCGATTACAACTGGTCAGAGCACCT
CGCGTTGATGGATGATGTCCGCGAATCCATTCACCTGCGCGCCATCGCCAGGGAAACCCCCCTTGATGAATACCACCGCA
TCGCTGTGCGTGAATTCAAGGATTTGGCACAACGCGCTGTCGATGATGCGGTGTCCACTTTCAAGTCTGTGACCATCGAT
CACGAGGGTGCACATTTGGATGATGAGGGCTTGGCGCGTCCATCGGCAACGTGGACCTACATGGTCTCTGACAACCCACT
CGCGGGTAGTGGCAACTCAGTGATCAGTGGCATAGGAAATATCTTTAGATAA

Upstream 100 bases:

>100_bases
TCTTACCCACCAGTGCAATGTAGGTCACGTCGTATCACGTCTGAGGGTGATTGAGTAGGGTTAAACAGATGAATTCATTT
AGCTCACCGGAGGTATAACC

Downstream 100 bases:

>100_bases
CCTGAGAACTATGAAATTCCAGCTCACGGCGTTTTTTCAGGAAATTCTAGGATCTTACGGAGGGTAACTCCGCACTCAAC
ATCTAGACAAAGGCTATGAT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MAGFDWFWKALGGKSGRNQKRSVAIVNQAENHVAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPY
PAQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAG
ERRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGR
VADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATNQLRTFYDLHVSVIERNHPLKRFD
EADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESV
SAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELE
DLDQSVREQAGRDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR

Sequences:

>Translated_763_residues
MAGFDWFWKALGGKSGRNQKRSVAIVNQAENHVAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPY
PAQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAG
ERRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGR
VADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATNQLRTFYDLHVSVIERNHPLKRFD
EADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESV
SAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELE
DLDQSVREQAGRDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
>Mature_762_residues
AGFDWFWKALGGKSGRNQKRSVAIVNQAENHVAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPYP
AQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGE
RRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRSL
KENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGRV
ADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATNQLRTFYDLHVSVIERNHPLKRFDE
ADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTVS
TQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESVS
AQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELED
LDQSVREQAGRDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTIDH
EGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=665, Percent_Identity=37.593984962406, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA2_CORGB (A4QIG3)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138394.1
- ProteinModelPortal:   A4QIG3
- SMR:   A4QIG3
- STRING:   A4QIG3
- GeneID:   4993020
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1500
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   QRVTEGQ
- ProtClustDB:   PRK12326
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 83459; Mature: 83328

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFDWFWKALGGKSGRNQKRSVAIVNQAENHVAELDALDDVALAQRAKDLASGGRIDNH
CCCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AEFLAILGVASQRTLGLKPYPAQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGK
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHCCHHHCC
RVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGERRQAYKAAIVYGPVNEIGF
CEEEEEECCEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHEEEEEECCHHHHHH
DVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHH
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIR
HHCCCCEEECCCCCEEEEECCCHHHHHHHCCCHHHCCCHHHCCEEEEEEHHHHHHHHHHH
DIHYIVRDSKVLLIDASRGRVADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIG
HHHHHHCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHC
RYPMACGMTGTAVEATNQLRTFYDLHVSVIERNHPLKRFDEADRIYATMAEKNRAIIDEI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHCCHHHHHHH
ALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCEEEE
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLS
EEEECCCCCEEEECCCCCCCHHHHHHHCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCE
LFFVSLDDDVVVSGGSGESVSAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNY
EEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELEDLDQSVREQAGRDIMLYHLD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEC
YNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AGFDWFWKALGGKSGRNQKRSVAIVNQAENHVAELDALDDVALAQRAKDLASGGRIDNH
CCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AEFLAILGVASQRTLGLKPYPAQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGK
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHCCHHHCC
RVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGERRQAYKAAIVYGPVNEIGF
CEEEEEECCEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHEEEEEECCHHHHHH
DVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHH
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIR
HHCCCCEEECCCCCEEEEECCCHHHHHHHCCCHHHCCCHHHCCEEEEEEHHHHHHHHHHH
DIHYIVRDSKVLLIDASRGRVADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIG
HHHHHHCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHC
RYPMACGMTGTAVEATNQLRTFYDLHVSVIERNHPLKRFDEADRIYATMAEKNRAIIDEI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHCCHHHHHHH
ALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCEEEE
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLS
EEEECCCCCEEEECCCCCCCHHHHHHHCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCE
LFFVSLDDDVVVSGGSGESVSAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNY
EEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELEDLDQSVREQAGRDIMLYHLD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEC
YNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA