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The map label for this gene is yciL [C]

Identifier: 145295560

GI number: 145295560

Start: 1647659

End: 1648621

Strand: Direct

Name: yciL [C]

Synonym: cgR_1487

Alternate gene names: 145295560

Gene position: 1647659-1648621 (Clockwise)

Preceding gene: 145295559

Following gene: 145295561

Centisome position: 49.72

GC content: 55.97

Gene sequence:

>963_bases
GTGACCCCACCCGCTCGCCGAGATGGCACACCGGACAAGAAGCAGAGCAATCGCTCTGGCGGATACCGGTCTTCAGTTCG
TGGCTACAAGCCAGGATCATCCCGCCCAAACACACGCCAGCAGCCTCAGAAGAAGGATGAGATTCTTCTCTCCAACGCTA
AGCCTGCCAAGAAGCAAAACGTAAAATCCGACGACGATTGGTCGATGGGTTTCTTAAGCCGCAATGACTCTGACGGAGTT
CGCCTGCAGAAGGTGCTTGCCCAAGCAGGTGTGGCATCACGTCGACACGCAGAAATCCTGATTGATCAGGGCCGTGTGGA
GGTCAACGATCGTATCGTGACCACCCAGGGCGTGCGCGTGAATCCAAACAACGATGTCATCCGTGTTGATGGCGTCCGCA
TCCACATCAACGAGGACCTCGAGTACTTCGTGCTCAACAAGCCTCGTGGCATGCACTCCACCATGAGCGATGAACTTGGT
CGCCCATGCGTGGGTGATCTGGTCAGTGAGAAGACTGCATCTGGACAGCGTCTGTTTCACGTCGGTCGTCTCGACGCGGA
CACCGAAGGTTTGCTGCTGCTCACCAACGATGGTGAGTTGGCTAACCGCCTCATGCACCCTAAGTACGAAGTGTCCAAGA
CTTACCTCGCTACCGTTCGCGGTGAAGCAACCAATAAGCTAGTCAGCGCTCTTCGTGATGGCGTGGAGTTGGAAGATGGC
CCTGCCAAGGCTGACTTTGCGCAGATCATCGACGTATTCCAGGGCAAGTCTCTGTTGCGCATCGAAATCCACGAAGGCCG
CAAGCACATTGTGCGACGCCTCTTCGATGAGCTCGGTTTCCCAGTCGAGCGCCTCGTGCGCACCAAGCTGCATACCGTTC
AGCTTGGTGATCAGAAGCCAGGTTCCCTTCGTGCACTGAACTCCTCTGAGCTGACCAGCTTATACAAGGTGGTCCAACTG
TGA

Upstream 100 bases:

>100_bases
AAGCATCAGTTAAAGCCCCGACTATTAAAATCTCCTAAAATAGGCTAGAATTCACGGGATTCAATTTCATACGTTTTCTC
TCAAGATTAAGGACACTTAC

Downstream 100 bases:

>100_bases
CGGAAGTTTCCAACATGCCTGCCGGTGGCCTCATCGTAGCCATCGACGGGCCGTCTGGCACCGGAAAATCCACCACATCC
CGCGCGCTCGCAACCCGTCT

Product: hypothetical protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTPPARRDGTPDKKQSNRSGGYRSSVRGYKPGSSRPNTRQQPQKKDEILLSNAKPAKKQNVKSDDDWSMGFLSRNDSDGV
RLQKVLAQAGVASRRHAEILIDQGRVEVNDRIVTTQGVRVNPNNDVIRVDGVRIHINEDLEYFVLNKPRGMHSTMSDELG
RPCVGDLVSEKTASGQRLFHVGRLDADTEGLLLLTNDGELANRLMHPKYEVSKTYLATVRGEATNKLVSALRDGVELEDG
PAKADFAQIIDVFQGKSLLRIEIHEGRKHIVRRLFDELGFPVERLVRTKLHTVQLGDQKPGSLRALNSSELTSLYKVVQL

Sequences:

>Translated_320_residues
MTPPARRDGTPDKKQSNRSGGYRSSVRGYKPGSSRPNTRQQPQKKDEILLSNAKPAKKQNVKSDDDWSMGFLSRNDSDGV
RLQKVLAQAGVASRRHAEILIDQGRVEVNDRIVTTQGVRVNPNNDVIRVDGVRIHINEDLEYFVLNKPRGMHSTMSDELG
RPCVGDLVSEKTASGQRLFHVGRLDADTEGLLLLTNDGELANRLMHPKYEVSKTYLATVRGEATNKLVSALRDGVELEDG
PAKADFAQIIDVFQGKSLLRIEIHEGRKHIVRRLFDELGFPVERLVRTKLHTVQLGDQKPGSLRALNSSELTSLYKVVQL
>Mature_319_residues
TPPARRDGTPDKKQSNRSGGYRSSVRGYKPGSSRPNTRQQPQKKDEILLSNAKPAKKQNVKSDDDWSMGFLSRNDSDGVR
LQKVLAQAGVASRRHAEILIDQGRVEVNDRIVTTQGVRVNPNNDVIRVDGVRIHINEDLEYFVLNKPRGMHSTMSDELGR
PCVGDLVSEKTASGQRLFHVGRLDADTEGLLLLTNDGELANRLMHPKYEVSKTYLATVRGEATNKLVSALRDGVELEDGP
AKADFAQIIDVFQGKSLLRIEIHEGRKHIVRRLFDELGFPVERLVRTKLHTVQLGDQKPGSLRALNSSELTSLYKVVQL

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=252, Percent_Identity=37.6984126984127, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790453, Length=242, Percent_Identity=32.6446280991736, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788510, Length=238, Percent_Identity=33.1932773109244, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI87081838, Length=183, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 35719; Mature: 35588

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50006 FHA_DOMAIN ; PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPARRDGTPDKKQSNRSGGYRSSVRGYKPGSSRPNTRQQPQKKDEILLSNAKPAKKQN
CCCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCHHHCC
VKSDDDWSMGFLSRNDSDGVRLQKVLAQAGVASRRHAEILIDQGRVEVNDRIVTTQGVRV
CCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCEEEECCEEEEECCEEE
NPNNDVIRVDGVRIHINEDLEYFVLNKPRGMHSTMSDELGRPCVGDLVSEKTASGQRLFH
CCCCCEEEECCEEEEECCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEE
VGRLDADTEGLLLLTNDGELANRLMHPKYEVSKTYLATVRGEATNKLVSALRDGVELEDG
ECCCCCCCCCEEEEECCHHHHHHHCCCCHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCC
PAKADFAQIIDVFQGKSLLRIEIHEGRKHIVRRLFDELGFPVERLVRTKLHTVQLGDQKP
CCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCC
GSLRALNSSELTSLYKVVQL
CCEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPARRDGTPDKKQSNRSGGYRSSVRGYKPGSSRPNTRQQPQKKDEILLSNAKPAKKQN
CCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCHHHCC
VKSDDDWSMGFLSRNDSDGVRLQKVLAQAGVASRRHAEILIDQGRVEVNDRIVTTQGVRV
CCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCEEEECCEEEEECCEEE
NPNNDVIRVDGVRIHINEDLEYFVLNKPRGMHSTMSDELGRPCVGDLVSEKTASGQRLFH
CCCCCEEEECCEEEEECCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEE
VGRLDADTEGLLLLTNDGELANRLMHPKYEVSKTYLATVRGEATNKLVSALRDGVELEDG
ECCCCCCCCCEEEEECCHHHHHHHCCCCHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCC
PAKADFAQIIDVFQGKSLLRIEIHEGRKHIVRRLFDELGFPVERLVRTKLHTVQLGDQKP
CCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCC
GSLRALNSSELTSLYKVVQL
CCEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]