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The map label for this gene is xerD [H]

Identifier: 145295553

GI number: 145295553

Start: 1640241

End: 1641155

Strand: Direct

Name: xerD [H]

Synonym: cgR_1480

Alternate gene names: 145295553

Gene position: 1640241-1641155 (Clockwise)

Preceding gene: 145295552

Following gene: 145295555

Centisome position: 49.49

GC content: 56.39

Gene sequence:

>915_bases
ATGAAGGCTCGCGTTTTGGCGAAAACATGGCTGACACATTTGGCCGTGGAGCGTGGCTTGTCGGCAAATACGCTGAGTAA
TTATCGGCGCGATGTGGAACGCTATTGCGACTGGCTCGAGGCAGCTGGGCTGGACGATATTCGTGATATCACCACCGCGC
ATGTGGAAAGTTATGTCAAAGACCTGCGCCGCGGGATTGATGGACAACAAGCGTTGTCTGCGTCCTCGGCAGGTCGCGCG
CTCATCGTGGCGCGCGGGTTGCACAAGTTTGCATTGATGGAGGGCGAGGTGGCTGCGGACGTTGCGGCTGATGTGTCGCC
ACCGGCCATGGGCCGGCATTTACCTGACACGCTCAGCATCAACGAGGTAGCCCTGCTTATCGACGCGATCCCACATTCAG
ATATCGCTACTCCCGTTGATCTCCGTGACCGAGCGCTGGTGGAATTACTTTATGGAACTGGCGCGCGTATCTCTGAGGCG
ATTGGGCTGGCAGTTGATGATGTGTCGGAAATGCCTGAAGTACTGCGCATCACGGGTAAAGGTTCCAAAAAACGGATCGT
GCCTTTTGGTTCGATGGCACAACAAGCGGTCCGGGAATATTTGATCAGAGCCAGACCCGCGTTGAGTAAGGGGAAAAGCC
ATGCGCTTTTTCTCAACCAACGCGGCGGTCCGCTATCTCGGCAATCTGCGTGGGCAGTGCTGAAGAAAACGGTTGAGCGC
GCAGGTTTAGATAAAGATATTTCTCCCCACACCCTGAGACACAGCTTCGCCACCCATCTCCTCGAAGGTGGCGCCGATGT
CCGTGTGGTGCAGGAACTCCTGGGTCATTCTTCTGTGACGACCACTCAGATTTACACGCACATCACAGCCGATAGCTTGC
GGGAAGTGTGGCGCGGGGCCCATCCTCGTGCGTGA

Upstream 100 bases:

>100_bases
GTGCGTCTGCGCGTGCCGTCACCGCGCCGTTTACCTATCGCCCTACGGCATTGGCGCAGCGTCGAAAAGCGCACGGCATT
GTTCCTGACATGAAAAAACT

Downstream 100 bases:

>100_bases
AAGCCCTTGCGAATTCTTAAGATTTCAACTCGATGTGCCTCCAATGAGCCGTATCGCGGAGTAGCTGTCGATCATGCGTC
ACCATGATCACTGCAGCCGT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKARVLAKTWLTHLAVERGLSANTLSNYRRDVERYCDWLEAAGLDDIRDITTAHVESYVKDLRRGIDGQQALSASSAGRA
LIVARGLHKFALMEGEVAADVAADVSPPAMGRHLPDTLSINEVALLIDAIPHSDIATPVDLRDRALVELLYGTGARISEA
IGLAVDDVSEMPEVLRITGKGSKKRIVPFGSMAQQAVREYLIRARPALSKGKSHALFLNQRGGPLSRQSAWAVLKKTVER
AGLDKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHITADSLREVWRGAHPRA

Sequences:

>Translated_304_residues
MKARVLAKTWLTHLAVERGLSANTLSNYRRDVERYCDWLEAAGLDDIRDITTAHVESYVKDLRRGIDGQQALSASSAGRA
LIVARGLHKFALMEGEVAADVAADVSPPAMGRHLPDTLSINEVALLIDAIPHSDIATPVDLRDRALVELLYGTGARISEA
IGLAVDDVSEMPEVLRITGKGSKKRIVPFGSMAQQAVREYLIRARPALSKGKSHALFLNQRGGPLSRQSAWAVLKKTVER
AGLDKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHITADSLREVWRGAHPRA
>Mature_304_residues
MKARVLAKTWLTHLAVERGLSANTLSNYRRDVERYCDWLEAAGLDDIRDITTAHVESYVKDLRRGIDGQQALSASSAGRA
LIVARGLHKFALMEGEVAADVAADVSPPAMGRHLPDTLSINEVALLIDAIPHSDIATPVDLRDRALVELLYGTGARISEA
IGLAVDDVSEMPEVLRITGKGSKKRIVPFGSMAQQAVREYLIRARPALSKGKSHALFLNQRGGPLSRQSAWAVLKKTVER
AGLDKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHITADSLREVWRGAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=299, Percent_Identity=40.133779264214, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=37.123745819398, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790767, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33149; Mature: 33149

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARVLAKTWLTHLAVERGLSANTLSNYRRDVERYCDWLEAAGLDDIRDITTAHVESYVK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DLRRGIDGQQALSASSAGRALIVARGLHKFALMEGEVAADVAADVSPPAMGRHLPDTLSI
HHHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCH
NEVALLIDAIPHSDIATPVDLRDRALVELLYGTGARISEAIGLAVDDVSEMPEVLRITGK
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCC
GSKKRIVPFGSMAQQAVREYLIRARPALSKGKSHALFLNQRGGPLSRQSAWAVLKKTVER
CCCCEECCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
AGLDKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHITADSLREVWRGA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
HPRA
CCCC
>Mature Secondary Structure
MKARVLAKTWLTHLAVERGLSANTLSNYRRDVERYCDWLEAAGLDDIRDITTAHVESYVK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DLRRGIDGQQALSASSAGRALIVARGLHKFALMEGEVAADVAADVSPPAMGRHLPDTLSI
HHHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCH
NEVALLIDAIPHSDIATPVDLRDRALVELLYGTGARISEAIGLAVDDVSEMPEVLRITGK
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCC
GSKKRIVPFGSMAQQAVREYLIRARPALSKGKSHALFLNQRGGPLSRQSAWAVLKKTVER
CCCCEECCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
AGLDKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHITADSLREVWRGA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
HPRA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]