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The map label for this gene is yvkA [H]

Identifier: 145295502

GI number: 145295502

Start: 1573058

End: 1574509

Strand: Reverse

Name: yvkA [H]

Synonym: cgR_1430

Alternate gene names: 145295502

Gene position: 1574509-1573058 (Counterclockwise)

Preceding gene: 145295503

Following gene: 145295501

Centisome position: 47.51

GC content: 56.27

Gene sequence:

>1452_bases
ATGTCACTTCCTGTTCAGCCGAGTAAAACCTCGGCCGCCACGGTCATACCATTGATGATCGCTCTGCTGGTCGCAGTATT
CGCCTTCCAGCTCAACGCCTCCATGCTGGCGCCGGCCCTTGCCACCATGGAAACTGAACTTAATGCAACAGCTGCTCAAA
TCGGCATGACTCAGACTGCTTTCTTCACCGCGGCCGCACTGTTTTCCCTGTTCCTGCCACGCTGGGGTGATCTGATTGGT
CGCCGCAAAGTGCTGGTCGGCATGATGATTGTCACCGGTATTGGATGTGTTGTCGCCGCCTTTGCTCCGAATGTGACCAT
CCTCTTCCTGGGCCGCCTGATTCAAGGTGTTGCTGGCCCAACCGTGCCACTCTGTCTGATCATTCTGCGCCAGCAGGTAA
CCAATGAAAAGCAATATGCGTTGCTTCTCGGAATTGTCACCTCTGTCAACGGTGGTATCGGCGGCGTGGACGCGCTTGCT
GGTGGCTGGCTGGCTGAAACGTTTGGTTTCCGTTCCATCTTCTGGGTCATGGCGGCCTTCTGTGCTGTCGCTGCCCTCTC
GCTCCCCTTCAGTGTGAAGGAATCCACCGCTGAAGAAACCCCAAAGATGGACTGGCTTGGTGTGCTGCCCCTGGCGGTAT
CCATCGGTTCCTTGCTCATGGCGTTCAACGAAGCAGGCAAGCTCGGTGCCGCTAACTGGATTCTGGTGGTTGTGCTGTTC
ATCATCGGTATCGCCGGAGTCATCTTCTTCTACAACATCGAAAAACGCGTTAAGCACCCGCTGGTCAGTGTCGAATACCT
CGGTCAACGACGCACCTGGGCATTGCTCCTGAGCACCCTTCTCACAATGACCGGTGTATTCGCCGTAATGAATGGTCTGC
TGCCCAACCTTGCGCAGGATGCTGCCAACGGTGCCGGCATGTCAGCGAGCGTGGTGTCCTGGTGGACACTTACCCCATAT
GCGCTGGCTGGCTTGGTATTCGGTCCAATCGCCGGAATTCTCGCCGGTAAATTTGGATACAAGATCGTCCTGCAAATTGG
TATCGCTGCCACCATCATCGGCGTTGCCGGAGCCACCTTCTTAGTCGGAAGCACCTCGCATCTCGCGTACCTCGGCATCT
CCATCTTCGTGGGTATTACCTATGCAGGTATTGCCAACATCATGCTCAATGGCCTGGGCATCGTACTCTCCCCTGCTAAT
AACCAAGGCTATCTGCCTGGCATGAACGCCGGTGCCTTCAACTTGGGTGCAGGTATTTCCTTCGCCATCCTCTTCGCAGT
CTCCACGGCATTCAGCGACAACGACGGAGGATACGCCGCAGGCATGTGGGCTGGCGTGATCATCTTGGTCCTCGCCTTCC
TCTGCTCCCTGCTGATCCCACGCCCAGAATCAATCACCGATACAGTGGCAGCCAAAGTCCAGGCTGAAGAAGCCGCTCAA
GCCGCCAGCTAA

Upstream 100 bases:

>100_bases
CGCGTTGGCGCTTATGCCGCCACCAAGCCGGGCGCTCAAGCCTCCTACCCCACCCTGACCACTGAACTCCCCTCAACCAC
TCACTGAAAAGAGAACACTG

Downstream 100 bases:

>100_bases
ATCCTCATACTTGAACTAAGGAGTTTTCCCCTATGACCACCAAGATCATCCTCGACTGCGATCCAGGACACGATGACGCT
GTAGCCATGCTGCTTTCAGC

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTAFFTAAALFSLFLPRWGDLIG
RRKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGPTVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALA
GGWLAETFGFRSIFWVMAAFCAVAALSLPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLF
IIGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQDAANGAGMSASVVSWWTLTPY
ALAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATFLVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPAN
NQGYLPGMNAGAFNLGAGISFAILFAVSTAFSDNDGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQ
AAS

Sequences:

>Translated_483_residues
MSLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTAFFTAAALFSLFLPRWGDLIG
RRKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGPTVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALA
GGWLAETFGFRSIFWVMAAFCAVAALSLPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLF
IIGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQDAANGAGMSASVVSWWTLTPY
ALAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATFLVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPAN
NQGYLPGMNAGAFNLGAGISFAILFAVSTAFSDNDGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQ
AAS
>Mature_482_residues
SLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTAFFTAAALFSLFLPRWGDLIGR
RKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGPTVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALAG
GWLAETFGFRSIFWVMAAFCAVAALSLPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLFI
IGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQDAANGAGMSASVVSWWTLTPYA
LAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATFLVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPANN
QGYLPGMNAGAFNLGAGISFAILFAVSTAFSDNDGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQA
AS

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50187; Mature: 50056

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FFTAAALFSLFLPRWGDLIGRRKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
TVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALAGGWLAETFGFRSIFWVMAAF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
CAVAALSLPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLF
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQD
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANGAGMSASVVSWWTLTPYALAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATF
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPANNQGYLPGMNAGAFNLGAGIS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
FAILFAVSTAFSDNDGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AAS
CCC
>Mature Secondary Structure 
SLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHH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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]