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The map label for this gene is ccpA [H]

Identifier: 145295390

GI number: 145295390

Start: 1459124

End: 1460233

Strand: Direct

Name: ccpA [H]

Synonym: cgR_1328

Alternate gene names: 145295390

Gene position: 1459124-1460233 (Clockwise)

Preceding gene: 145295389

Following gene: 145295391

Centisome position: 44.03

GC content: 52.43

Gene sequence:

>1110_bases
ATGGCTTCCGAAACCTCCAGCCCGAAGAAGCGGGCCACCACACTCAAAGACATCGCGCAAACAACACAGCTTTCAGTCAG
CACGGTGTCCCGGGCATTGGCCAACAACGCGAGCATTCCGGAATCCACACGCATCCGAGTGGTTGAAGCCGCTCAAAAGC
TGAACTACCGTCCCAATGCCCAAGCTCGTGCATTGCGGAAGTCGAGGACAGACACCATCGGTGTCATCATTCCAAACATT
GAGAACCCATATTTCTCCTCACTAGCAGCATCGATTCAAAAAGCTGCTCGTGAAGCTGGGGTGTCCACCATTTTGTCCAA
CTCTGAAGAAAACCCAGAGCTGCTTGGTCAGACTTTGGCGATCATGGATGACCAACGCCTCGATGGAATCATCGTGGTGC
CACACATTCAGTCAGAGGAACAAGTCACTGACTTGGTTACCAGGGGAGTGCCAGTAGTGCTGGCAGACCGTAGTTTTGTT
AACTCGTCTATTCCTTCGGTTACCTCAGATCCAGTTCCGGGCATGACTGAAGCTGTGGACTTACTCCTGGCAGCTGACGT
GCAATTGGGCTACCTTGCCGGCCCGCAGGATACTTCCACTGGTCAGCTGCGTCTTAACACTTTTGAAAGACTATGCGTGG
ACCGCGGCATCGTCGGAGCATCTGTCTATTACGGTGGCTACCGCCAAGAATCTGGATATGACGGCATCAAGGTGCTGATC
AAACAGGGAGCCAATGCGATTATCGCTGGTGACTCCATGATGACCATCGGTGCGTTGTTGGCTCTTCATGAGATGAATTT
GAAGATCGGTGAGGATGTGCAGCTCATTGGGTTTGATAACAACCCAATTTTCCGGCTGCAGAATCCACCGCTGAGCATCA
TTGACCAGCACGTACAAGAGATCGGTAAGCGTGCGTTTGAGATTCTGCAGAAGCTGATCAATGGGGACACCGCGCAAAAA
TCTGTGGTGATTCCAACGCAGCTCAGCATCAATGGATCAACGGCGGTTTCCCAAAAGGCCGCCGCAAAGGCAGCAAAAGC
AGCCCAAAAAGCAGCCGCGAAAGCCACACAGAACACGCAACACGAGGTGAGCCTAGATGGTGAACTCTGA

Upstream 100 bases:

>100_bases
TGGGGGAGTGGGGATAAGTTCATCTTAAACACAATGCAATCGATTGCATTTACATTCCTTATCCCACAATAGGGGTACCT
TCCAGAAAGTTGGTGAGGAG

Downstream 100 bases:

>100_bases
ACAAGCGCTTCATCAGCATGATCCTGCACCAATCCTTCAGTTGGATAAAGTCTCCAAGTCGTTTGGCCCAGTCAACGTCA
TTAATCAGGTGAGCATCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MASETSSPKKRATTLKDIAQTTQLSVSTVSRALANNASIPESTRIRVVEAAQKLNYRPNAQARALRKSRTDTIGVIIPNI
ENPYFSSLAASIQKAAREAGVSTILSNSEENPELLGQTLAIMDDQRLDGIIVVPHIQSEEQVTDLVTRGVPVVLADRSFV
NSSIPSVTSDPVPGMTEAVDLLLAADVQLGYLAGPQDTSTGQLRLNTFERLCVDRGIVGASVYYGGYRQESGYDGIKVLI
KQGANAIIAGDSMMTIGALLALHEMNLKIGEDVQLIGFDNNPIFRLQNPPLSIIDQHVQEIGKRAFEILQKLINGDTAQK
SVVIPTQLSINGSTAVSQKAAAKAAKAAQKAAAKATQNTQHEVSLDGEL

Sequences:

>Translated_369_residues
MASETSSPKKRATTLKDIAQTTQLSVSTVSRALANNASIPESTRIRVVEAAQKLNYRPNAQARALRKSRTDTIGVIIPNI
ENPYFSSLAASIQKAAREAGVSTILSNSEENPELLGQTLAIMDDQRLDGIIVVPHIQSEEQVTDLVTRGVPVVLADRSFV
NSSIPSVTSDPVPGMTEAVDLLLAADVQLGYLAGPQDTSTGQLRLNTFERLCVDRGIVGASVYYGGYRQESGYDGIKVLI
KQGANAIIAGDSMMTIGALLALHEMNLKIGEDVQLIGFDNNPIFRLQNPPLSIIDQHVQEIGKRAFEILQKLINGDTAQK
SVVIPTQLSINGSTAVSQKAAAKAAKAAQKAAAKATQNTQHEVSLDGEL
>Mature_368_residues
ASETSSPKKRATTLKDIAQTTQLSVSTVSRALANNASIPESTRIRVVEAAQKLNYRPNAQARALRKSRTDTIGVIIPNIE
NPYFSSLAASIQKAAREAGVSTILSNSEENPELLGQTLAIMDDQRLDGIIVVPHIQSEEQVTDLVTRGVPVVLADRSFVN
SSIPSVTSDPVPGMTEAVDLLLAADVQLGYLAGPQDTSTGQLRLNTFERLCVDRGIVGASVYYGGYRQESGYDGIKVLIK
QGANAIIAGDSMMTIGALLALHEMNLKIGEDVQLIGFDNNPIFRLQNPPLSIIDQHVQEIGKRAFEILQKLINGDTAQKS
VVIPTQLSINGSTAVSQKAAAKAAKAAQKAAAKATQNTQHEVSLDGEL

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=324, Percent_Identity=28.0864197530864, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789068, Length=309, Percent_Identity=30.0970873786408, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790194, Length=316, Percent_Identity=27.2151898734177, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790369, Length=333, Percent_Identity=28.2282282282282, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788474, Length=337, Percent_Identity=28.1899109792285, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787580, Length=328, Percent_Identity=27.1341463414634, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789202, Length=288, Percent_Identity=25, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786540, Length=325, Percent_Identity=24.9230769230769, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789456, Length=340, Percent_Identity=24.4117647058824, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=23.1231231231231, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=22.9813664596273, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=23.4375, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786268, Length=305, Percent_Identity=23.6065573770492, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790715, Length=336, Percent_Identity=23.2142857142857, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 39422; Mature: 39291

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASETSSPKKRATTLKDIAQTTQLSVSTVSRALANNASIPESTRIRVVEAAQKLNYRPNA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCH
QARALRKSRTDTIGVIIPNIENPYFSSLAASIQKAAREAGVSTILSNSEENPELLGQTLA
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
IMDDQRLDGIIVVPHIQSEEQVTDLVTRGVPVVLADRSFVNSSIPSVTSDPVPGMTEAVD
HHCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCCCHHHHHH
LLLAADVQLGYLAGPQDTSTGQLRLNTFERLCVDRGIVGASVYYGGYRQESGYDGIKVLI
HHHHHCCEEEEECCCCCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHH
KQGANAIIAGDSMMTIGALLALHEMNLKIGEDVQLIGFDNNPIFRLQNPPLSIIDQHVQE
HCCCCEEEECCHHHHHHHHHHHHHCCCEECCCEEEEEECCCCEEEECCCCHHHHHHHHHH
IGKRAFEILQKLINGDTAQKSVVIPTQLSINGSTAVSQKAAAKAAKAAQKAAAKATQNTQ
HHHHHHHHHHHHHCCCCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
HEVSLDGEL
CEEECCCCC
>Mature Secondary Structure 
ASETSSPKKRATTLKDIAQTTQLSVSTVSRALANNASIPESTRIRVVEAAQKLNYRPNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCH
QARALRKSRTDTIGVIIPNIENPYFSSLAASIQKAAREAGVSTILSNSEENPELLGQTLA
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
IMDDQRLDGIIVVPHIQSEEQVTDLVTRGVPVVLADRSFVNSSIPSVTSDPVPGMTEAVD
HHCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCCCHHHHHH
LLLAADVQLGYLAGPQDTSTGQLRLNTFERLCVDRGIVGASVYYGGYRQESGYDGIKVLI
HHHHHCCEEEEECCCCCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHH
KQGANAIIAGDSMMTIGALLALHEMNLKIGEDVQLIGFDNNPIFRLQNPPLSIIDQHVQE
HCCCCEEEECCHHHHHHHHHHHHHCCCEECCCEEEEEECCCCEEEECCCCHHHHHHHHHH
IGKRAFEILQKLINGDTAQKSVVIPTQLSINGSTAVSQKAAAKAAKAAQKAAAKATQNTQ
HHHHHHHHHHHHHCCCCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
HEVSLDGEL
CEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]