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The map label for this gene is atpA

Identifier: 145295349

GI number: 145295349

Start: 1417776

End: 1419419

Strand: Direct

Name: atpA

Synonym: cgR_1288

Alternate gene names: 145295349

Gene position: 1417776-1419419 (Clockwise)

Preceding gene: 145295348

Following gene: 145295350

Centisome position: 42.78

GC content: 58.52

Gene sequence:

>1644_bases
ATGGCGGAGCTGACGATCTCCTCCGATGAGATCCGTAGCGCGATTGCGAACTACACCTCGAGCTACTCCGCGGAGGCCTC
CCGTGAGGAGGTCGGCGTGGTTATTTCGGCCGCTGACGGTATCGCCCAGGTTTCGGGCCTCCCGTCAGTAATGGCGAATG
AGCTCCTCGAATTCCCGGGCGGCGTCATCGGCGTCGCACAGAACCTTGAAGCTGACCGAGTCGGCGTCGTGGTCCTGGGT
AACTACGAGCTACTTAAAGAAGGCGACCAAGTTCGTCGTACTGGAGACGTTCTGTCTATCCCAGTCGGCGAGGCATTCCT
TGGCCGCGTTATCAACCCCCTTGGCCAGCCAATTGACGGCCTGGGCGAAATTGCATCCGAAGAGGACCGCGTCCTCGAGC
TTCAGGCACCAACCGTGCTTGAGCGCCAGCCTGTCGAGGAGCCTTTGGCAACCGGCATCAAGGCTATCGATGCAATGACC
CCAATCGGCCGCGGTCAGCGTCAGCTGATCATTGGTGACCGTAAGACTGGCAAGACCGCAGTCTGCGTCGATACCATCCT
TAACCAGAAGGCCAACTGGGAGACCGGCGACAAGACCAAGCAGGTTCGCTGCATCTACGTCGCAATCGGTCAGAAGGGCT
CCACCATTGCAGCCCTGCGTAAGACCCTCGAGGAGCAGGGCGCTCTCGAGTACACCACCATCGTGGCTGCACCCGCTTCC
GATGCTGCAGGCTTCAAGTGGCTTGCACCATTCGCTGGCGCTGCTCTCGCCCAGCACTGGATGTACCAGGGCAACCACGT
CCTGGTCATCTACGATGATCTGACCAAGCAGGCTGAGGCCTACCGTGCCATCTCCCTGCTGCTGCGCCGCCCACCAGGCC
GCGAAGCATACCCAGGTGACGTCTTCTACCTGCACTCCCGTCTGCTGGAGCGCGCTGCGAAGCTGTCTGATGATCTCGGT
GCAGGTTCCATTACCGCACTGCCAATCATTGAGACCAAGGCTAACGACGTTTCCGCCTTCATTCCCACCAACGTGATTTC
CATCACCGACGGTCAGGTATTCCTTGAGTCCGACCTGTTCAACCGTGGCATTCGCCCGGCGATCAACGTCGGTGTATCCG
TCTCCCGTGTCGGTGGCGCAGCTCAGACCAAGGGTATGAAGAAGGTTGCCGGTTCTCTCCGTCTGGATCTGGCTGCATTC
CGCGACCTGGAAGCATTCGCTACCTTCGCATCTGACTTGGATGCTGCATCCAAGTCTCAGCTTGAGCGTGGCCAGCGCCT
CGTTCAGCTGTTGATTCAGTCTGAGAACGCACCTCAGGCTGTTGAGTACCAGATCATTTCTCTCTGGCTTGCAGGCGAAG
GCGCATTCGACAACGTTCCTGTTGAAGATGTTCGTCGCTTCGAGTCCGAACTGCACGAGTACTTGGGCTCCAACGCTGCA
CAGGTCTACGAGCAGATCGCTGGTGGAGCTCAGCTTTCCGACGAGTCCAAGGAAACCTTGCTCAAGGCAACCGAAGATTT
CAAGAGCGCTTTCCAGACCACCGATGGCACCCCTGTCATCAACGAGCCTGAGGTTGAAGCACTCGATGCAGGCCAGGTCA
AGAAAGACCAGCTCACCGTTTCCCGCAAGGTCAGCAAGAAGTAA

Upstream 100 bases:

>100_bases
TCGGGCAAACTCGAGCGTCTGCGGGCAAGCTTCGCATAAAGACACGACGAATTAGACAACATTAGTAATGCTGGAAGAAA
CAACCGAGAGCAGGAAGAAC

Downstream 100 bases:

>100_bases
GGCAGCGAGCCTACACTAAATGACTGTCCAAGCAACTGAAGGGAGGCGTGTGAACCATGGCAACAATTCGTGAATTGCGT
GACCGAATTCGTTCGGTTAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MAELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPGGVIGVAQNLEADRVGVVVLG
NYELLKEGDQVRRTGDVLSIPVGEAFLGRVINPLGQPIDGLGEIASEEDRVLELQAPTVLERQPVEEPLATGIKAIDAMT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQKANWETGDKTKQVRCIYVAIGQKGSTIAALRKTLEEQGALEYTTIVAAPAS
DAAGFKWLAPFAGAALAQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLG
AGSITALPIIETKANDVSAFIPTNVISITDGQVFLESDLFNRGIRPAINVGVSVSRVGGAAQTKGMKKVAGSLRLDLAAF
RDLEAFATFASDLDAASKSQLERGQRLVQLLIQSENAPQAVEYQIISLWLAGEGAFDNVPVEDVRRFESELHEYLGSNAA
QVYEQIAGGAQLSDESKETLLKATEDFKSAFQTTDGTPVINEPEVEALDAGQVKKDQLTVSRKVSKK

Sequences:

>Translated_547_residues
MAELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPGGVIGVAQNLEADRVGVVVLG
NYELLKEGDQVRRTGDVLSIPVGEAFLGRVINPLGQPIDGLGEIASEEDRVLELQAPTVLERQPVEEPLATGIKAIDAMT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQKANWETGDKTKQVRCIYVAIGQKGSTIAALRKTLEEQGALEYTTIVAAPAS
DAAGFKWLAPFAGAALAQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLG
AGSITALPIIETKANDVSAFIPTNVISITDGQVFLESDLFNRGIRPAINVGVSVSRVGGAAQTKGMKKVAGSLRLDLAAF
RDLEAFATFASDLDAASKSQLERGQRLVQLLIQSENAPQAVEYQIISLWLAGEGAFDNVPVEDVRRFESELHEYLGSNAA
QVYEQIAGGAQLSDESKETLLKATEDFKSAFQTTDGTPVINEPEVEALDAGQVKKDQLTVSRKVSKK
>Mature_546_residues
AELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPGGVIGVAQNLEADRVGVVVLGN
YELLKEGDQVRRTGDVLSIPVGEAFLGRVINPLGQPIDGLGEIASEEDRVLELQAPTVLERQPVEEPLATGIKAIDAMTP
IGRGQRQLIIGDRKTGKTAVCVDTILNQKANWETGDKTKQVRCIYVAIGQKGSTIAALRKTLEEQGALEYTTIVAAPASD
AAGFKWLAPFAGAALAQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGA
GSITALPIIETKANDVSAFIPTNVISITDGQVFLESDLFNRGIRPAINVGVSVSRVGGAAQTKGMKKVAGSLRLDLAAFR
DLEAFATFASDLDAASKSQLERGQRLVQLLIQSENAPQAVEYQIISLWLAGEGAFDNVPVEDVRRFESELHEYLGSNAAQ
VYEQIAGGAQLSDESKETLLKATEDFKSAFQTTDGTPVINEPEVEALDAGQVKKDQLTVSRKVSKK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=484, Percent_Identity=53.9256198347107, Blast_Score=539, Evalue=1e-153,
Organism=Homo sapiens, GI4757810, Length=484, Percent_Identity=53.9256198347107, Blast_Score=539, Evalue=1e-153,
Organism=Homo sapiens, GI19913428, Length=324, Percent_Identity=31.1728395061728, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI19913426, Length=323, Percent_Identity=30.030959752322, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI32189394, Length=378, Percent_Identity=25.6613756613757, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19913424, Length=259, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790172, Length=517, Percent_Identity=48.936170212766, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1788251, Length=319, Percent_Identity=29.4670846394984, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790170, Length=315, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=484, Percent_Identity=53.7190082644628, Blast_Score=546, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI71988080, Length=484, Percent_Identity=53.7190082644628, Blast_Score=545, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI71988074, Length=484, Percent_Identity=50.6198347107438, Blast_Score=493, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17570191, Length=322, Percent_Identity=30.4347826086957, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17510931, Length=346, Percent_Identity=29.1907514450867, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25144756, Length=326, Percent_Identity=26.0736196319018, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=54.0755467196819, Blast_Score=541, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6319603, Length=341, Percent_Identity=30.791788856305, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322581, Length=437, Percent_Identity=25.1716247139588, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24658560, Length=508, Percent_Identity=52.9527559055118, Blast_Score=546, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=309, Percent_Identity=31.3915857605178, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24646341, Length=309, Percent_Identity=31.3915857605178, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI17136796, Length=309, Percent_Identity=31.3915857605178, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24638766, Length=326, Percent_Identity=26.0736196319018, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28574560, Length=411, Percent_Identity=24.0875912408759, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_CORGB (A4QDH1)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138170.1
- ProteinModelPortal:   A4QDH1
- SMR:   A4QDH1
- STRING:   A4QDH1
- GeneID:   4993321
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1288
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 58751; Mature: 58620

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPG
CCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHCCC
GVIGVAQNLEADRVGVVVLGNYELLKEGDQVRRTGDVLSIPVGEAFLGRVINPLGQPIDG
CEEEHHCCCCCCCCCEEEECCHHHHHCCHHHHHCCCEEEECCCHHHHHHHHHHHCCCHHH
LGEIASEEDRVLELQAPTVLERQPVEEPLATGIKAIDAMTPIGRGQRQLIIGDRKTGKTA
HHHHCCCCCCEEEECCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCH
VCVDTILNQKANWETGDKTKQVRCIYVAIGQKGSTIAALRKTLEEQGALEYTTIVAAPAS
HHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCC
DAAGFKWLAPFAGAALAQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGD
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERAAKLSDDLGAGSITALPIIETKANDVSAFIPTNVISITDGQVFLESDLF
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEECCCCEEEECCCCEEEECHHH
NRGIRPAINVGVSVSRVGGAAQTKGMKKVAGSLRLDLAAFRDLEAFATFASDLDAASKSQ
HCCCCCHHHCCEEHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGQRLVQLLIQSENAPQAVEYQIISLWLAGEGAFDNVPVEDVRRFESELHEYLGSNAA
HHHHHHHHHHHHHCCCCCCHHEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHH
QVYEQIAGGAQLSDESKETLLKATEDFKSAFQTTDGTPVINEPEVEALDAGQVKKDQLTV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SRKVSKK
HHHHCCC
>Mature Secondary Structure 
AELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPG
CEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHCCC
GVIGVAQNLEADRVGVVVLGNYELLKEGDQVRRTGDVLSIPVGEAFLGRVINPLGQPIDG
CEEEHHCCCCCCCCCEEEECCHHHHHCCHHHHHCCCEEEECCCHHHHHHHHHHHCCCHHH
LGEIASEEDRVLELQAPTVLERQPVEEPLATGIKAIDAMTPIGRGQRQLIIGDRKTGKTA
HHHHCCCCCCEEEECCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCH
VCVDTILNQKANWETGDKTKQVRCIYVAIGQKGSTIAALRKTLEEQGALEYTTIVAAPAS
HHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCC
DAAGFKWLAPFAGAALAQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGD
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERAAKLSDDLGAGSITALPIIETKANDVSAFIPTNVISITDGQVFLESDLF
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEECCCCEEEECCCCEEEECHHH
NRGIRPAINVGVSVSRVGGAAQTKGMKKVAGSLRLDLAAFRDLEAFATFASDLDAASKSQ
HCCCCCHHHCCEEHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGQRLVQLLIQSENAPQAVEYQIISLWLAGEGAFDNVPVEDVRRFESELHEYLGSNAA
HHHHHHHHHHHHHCCCCCCHHEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHH
QVYEQIAGGAQLSDESKETLLKATEDFKSAFQTTDGTPVINEPEVEALDAGQVKKDQLTV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SRKVSKK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA