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The map label for this gene is wecA [H]

Identifier: 145295342

GI number: 145295342

Start: 1412816

End: 1413964

Strand: Direct

Name: wecA [H]

Synonym: cgR_1282

Alternate gene names: 145295342

Gene position: 1412816-1413964 (Clockwise)

Preceding gene: 145295341

Following gene: 145295343

Centisome position: 42.63

GC content: 56.31

Gene sequence:

>1149_bases
ATGGGAGTCGGTTTCGCGGGAATCCCGCTGCGCGAATTGGGATTGGTGATCCTCGTTGCAGCGGCCATCACGTATCTCAG
CACAGGCATCATCCGCACCGTCATGGTGAAAAGTGGTCGCCTCAATGAGATTCGTGAACGAGACGTCCATGTCATCCCCA
AACCACGGCTTGGTGGTGTGGCGATGTTCAGTGGATTTCTCGGCGCAGTATTCCTTGCGGACCAGCTTCCCGCCTTGACT
CGCGGGTTCATGCCCATCACCCCGGAGATGAATGCCGTCATTTGGGCAGGCTTTGTCATCGTGGTGGTGGGCGCACTGGA
TGACCTTTTCGATCTTGATGCCATCACTAAATTGGTGGGACAAGTAATTGGTGCGGTGACCATGAGTTTGCTTGGTCTCA
CGTGGTCCATTCTCTACGTTCCCTTTGGCGGGGGAACCACATTACTTCTAGATCAAGTCCAGTCAACAATCTTGACATCC
CTGTTCACCGTGGCGTTGATTAATGCTCTGAACTTCGTGGACGGCCTAGACGGCTTGAGTGCCGGCGTAGGAATGATCGC
GGGTGCAGCCATCCTGCTGTTCTCCCTGACGATTCTCTTCGACCAAAACGGCGCCGTATCGGCCTATCCGCCGGCCATCA
TCGCAGCGGCTCTCGTAGGAATTTGCGCGGGAGTTTTGCCCCATAATTTTGAGCCCTCGCGAATATTTATGGGCGATTCC
GGTTCCATGCTCATCGGCCTGCTGTTGGCTGCAGCATCGACCTCAGCGTCAGGAAAAATCAACATGAGCCTGTATGGCGC
AGCTGATTTTATCGCATTGATCTCACCCATCATCGTTGTTTTAGCCGCCGTGGCCATCCCACTGCTCGACCTCGTGATGG
CAGTGGTTAGGCGCGTGGGCAGGGGAGCATCACCCTTTTCCCCGGACAAAATGCATCTGCACCACCGACTGCTGTCCATC
GGACACACCCATAGGCGCGTGGTCCTAGTGCTCTACACCTGGGCGAGCGCCGTGGCATTCGGCGCAGTGAGCTTCTCCGT
CGTTCCGCCACTGTTTGCCACCGGATCGAGCATCTGTGGCATCCTCATCGCCGTCGCTGTCACAGCCGTGCCAGTGATGA
AAAGCCGGCGAGCCGCCAAACTTGATTAA

Upstream 100 bases:

>100_bases
TGATATCTCCGGCCCCGCACCGAAGATTTTGCGTGAGGGCGCCATCAGCGCAGAACGCGTTGGCGAAGTACTTGGAGTGT
CGGCAGAAAGCCTGCGCTAA

Downstream 100 bases:

>100_bases
GTGATTGTCACTTTGGATTGTCATATTGGGCGAATGAACCGGTAGGATTCCCCTTCGTGAGCGCCGAAAATACCGAGAAC
ACAGATTCCCCATTTGAAAT

Product: hypothetical protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MGVGFAGIPLRELGLVILVAAAITYLSTGIIRTVMVKSGRLNEIRERDVHVIPKPRLGGVAMFSGFLGAVFLADQLPALT
RGFMPITPEMNAVIWAGFVIVVVGALDDLFDLDAITKLVGQVIGAVTMSLLGLTWSILYVPFGGGTTLLLDQVQSTILTS
LFTVALINALNFVDGLDGLSAGVGMIAGAAILLFSLTILFDQNGAVSAYPPAIIAAALVGICAGVLPHNFEPSRIFMGDS
GSMLIGLLLAAASTSASGKINMSLYGAADFIALISPIIVVLAAVAIPLLDLVMAVVRRVGRGASPFSPDKMHLHHRLLSI
GHTHRRVVLVLYTWASAVAFGAVSFSVVPPLFATGSSICGILIAVAVTAVPVMKSRRAAKLD

Sequences:

>Translated_382_residues
MGVGFAGIPLRELGLVILVAAAITYLSTGIIRTVMVKSGRLNEIRERDVHVIPKPRLGGVAMFSGFLGAVFLADQLPALT
RGFMPITPEMNAVIWAGFVIVVVGALDDLFDLDAITKLVGQVIGAVTMSLLGLTWSILYVPFGGGTTLLLDQVQSTILTS
LFTVALINALNFVDGLDGLSAGVGMIAGAAILLFSLTILFDQNGAVSAYPPAIIAAALVGICAGVLPHNFEPSRIFMGDS
GSMLIGLLLAAASTSASGKINMSLYGAADFIALISPIIVVLAAVAIPLLDLVMAVVRRVGRGASPFSPDKMHLHHRLLSI
GHTHRRVVLVLYTWASAVAFGAVSFSVVPPLFATGSSICGILIAVAVTAVPVMKSRRAAKLD
>Mature_381_residues
GVGFAGIPLRELGLVILVAAAITYLSTGIIRTVMVKSGRLNEIRERDVHVIPKPRLGGVAMFSGFLGAVFLADQLPALTR
GFMPITPEMNAVIWAGFVIVVVGALDDLFDLDAITKLVGQVIGAVTMSLLGLTWSILYVPFGGGTTLLLDQVQSTILTSL
FTVALINALNFVDGLDGLSAGVGMIAGAAILLFSLTILFDQNGAVSAYPPAIIAAALVGICAGVLPHNFEPSRIFMGDSG
SMLIGLLLAAASTSASGKINMSLYGAADFIALISPIIVVLAAVAIPLLDLVMAVVRRVGRGASPFSPDKMHLHHRLLSIG
HTHRRVVLVLYTWASAVAFGAVSFSVVPPLFATGSSICGILIAVAVTAVPVMKSRRAAKLD

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55), the lipid intermediate involved in the synthesis of various bacter

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=309, Percent_Identity=30.42071197411, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39750; Mature: 39619

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVGFAGIPLRELGLVILVAAAITYLSTGIIRTVMVKSGRLNEIRERDVHVIPKPRLGGV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEECCCCCCCHH
AMFSGFLGAVFLADQLPALTRGFMPITPEMNAVIWAGFVIVVVGALDDLFDLDAITKLVG
HHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVIGAVTMSLLGLTWSILYVPFGGGTTLLLDQVQSTILTSLFTVALINALNFVDGLDGLS
HHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AGVGMIAGAAILLFSLTILFDQNGAVSAYPPAIIAAALVGICAGVLPHNFEPSRIFMGDS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GSMLIGLLLAAASTSASGKINMSLYGAADFIALISPIIVVLAAVAIPLLDLVMAVVRRVG
CHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGASPFSPDKMHLHHRLLSIGHTHRRVVLVLYTWASAVAFGAVSFSVVPPLFATGSSICG
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHCCHHHHH
ILIAVAVTAVPVMKSRRAAKLD
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GVGFAGIPLRELGLVILVAAAITYLSTGIIRTVMVKSGRLNEIRERDVHVIPKPRLGGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEECCCCCCCHH
AMFSGFLGAVFLADQLPALTRGFMPITPEMNAVIWAGFVIVVVGALDDLFDLDAITKLVG
HHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVIGAVTMSLLGLTWSILYVPFGGGTTLLLDQVQSTILTSLFTVALINALNFVDGLDGLS
HHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AGVGMIAGAAILLFSLTILFDQNGAVSAYPPAIIAAALVGICAGVLPHNFEPSRIFMGDS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GSMLIGLLLAAASTSASGKINMSLYGAADFIALISPIIVVLAAVAIPLLDLVMAVVRRVG
CHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGASPFSPDKMHLHHRLLSIGHTHRRVVLVLYTWASAVAFGAVSFSVVPPLFATGSSICG
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHCCHHHHH
ILIAVAVTAVPVMKSRRAAKLD
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]