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The map label for this gene is rho [H]

Identifier: 145295338

GI number: 145295338

Start: 1407917

End: 1410199

Strand: Direct

Name: rho [H]

Synonym: cgR_1278

Alternate gene names: 145295338

Gene position: 1407917-1410199 (Clockwise)

Preceding gene: 145295330

Following gene: 145295339

Centisome position: 42.48

GC content: 55.63

Gene sequence:

>2283_bases
GTGACAACCACAGACAACACCGCAGCGAATCAGGGTGAACTGACCGCCCTCCGACTGCCGGATCTGCGCAAAATTGCCGC
CGACCTTGGGCTCAAGGGAACCTCGGCATTGCGTAAGGGCGATCTGATCAACGCCATCTCTGCAGCCCGCGAGGGTAAGC
CAACCGCAGCTGCGAAGAAGACTTCCCCACGCAAGGCCCCATCACGCACCCGTGTGACACAGCCTTCCGCACCGGTTGAG
CAAGCACAAGAAGCTCCCGCGCAAACTTCAACTGCACCTGCTTCAGCACCATCTGAAGAGACTCCCGCAGCTCCCGCTCG
TCGTGGACGTCGCCGTGTAACCACCACCGCGACCACCCCAGAGCCAGCAGCGCCTGCACAATCCCAGCCTGCAGAAGCTC
AACCAGCACAGACTCAGGCTGCACAGCAAGAAGAACTTCCTGTTGCAGCGAAGGAGTCCGCACCAGCTACAGAAAATACT
CAGGGCCAATCCCAGGGCCAAGCTCAGGGCGATGAGCACGATGATCGCTTTGAGTCCCGTTCTGCTGCACGCCGAGCACG
CCGCAACCGTCAGCGCCAGATCCACCGCGATGGCGATGACAATGCGAATGCAAACACAGAGTCTGAGCAGAACACCCCTG
CCCAGAACGCAACCGCACAGGCTGAGTCTGAGCAGACTGCAGCTCCTGCACAGGCTGAAGCAGCTGAGCAGAACCAGAAC
GATAACAGTGAGTCCTCCGAGAACCGCAGCGATAACTACCGCAACAACAATCGTCGTTCCCGCAACAACCGGAACAATCG
CAATTACCGCGATAACAACGAGTCCTCTGATAATGCAGGACAGTCCAGCAATGATGATGCCGACAACAATCAGGCACGGT
CTGAGGACAATAACGACGATCGCCGTTCTCGTAATAACCGTAACAACGACCGCAATGATCGTAACGATCGCAATGACCGC
GACAACCACAACGACGACAACGATGATCGCCGCAACCGTCGCGGACGCCGTAATCGCCGTGGACGCAACGACCGTAACGA
TCGCGACAACCGAGATAACCGGGATAACCGCGACAACAGCAACGATGGCGACAACAACCAGCAAGATGAGCTGCAGCAGG
TAGCAGGCATCCTGGACATCGTGGACCATAACGTCGCATTCGTGCGCACCACCGGTTACCACGCTGCACCTTCTGACGTG
TTTGTCAGCAACCAGCTGATCCGCCGTATGGGTCTTCGTTCCGGTGACGCCATTGAAGGTCAGGTTCGTATGAACCAGGG
TGGTGGCAACCACAACAACCATGGTCGCAACCGTCAGAAGTACAACAACTTGGTGCGCGTGGAGATGGTTAACGGTCTTC
CTGCGGAAGAGACTCGCAACCGTCCTGAGTTCGGCAAGCTGACTCCTCTGTACCCGAACCAGCGTCTGCGTTTGGAAACT
GAGCAGAAGATTCTTACCACTCGTGTGATCGACTTGATCATGCCTATTGGTAAGGGACAGCGTGCTTTGATTGTGTCGCC
ACCTAAGGCTGGTAAGACCACGATCCTGCAGAACATTGCGAACGCTATTTCCACCAACAACCCAGAGTGCTACCTCATGG
TTGTTTTGGTTGATGAGCGTCCGGAAGAAGTTACTGATATGCAGCGCTCCGTCAACGGCGAAGTGATTGCTTCTACTTTC
GATCGTCCACCATCAGAGCACACTGCGGTTGCTGAGCTGGCGATTGAGCGTGCGAAGCGCCTGGTGGAGCAGGGCCAGGA
CGTCGTTGTTCTGCTTGACTCCATTACTCGTTTGGGCCGTGCGTACAACAACAGCTCACCTGCATCGGGACGTATTTTGT
CCGGTGGTGTGGATTCCAATGCACTGTACCCGCCGAAGCGTTTCTTGGGTGCTGCTCGAAACATCGAAAATGGTGGATCT
TTGACCATCATCGCAACTGCCATGGTGGAGACCGGCTCTGCTGGTGACACCGTGATCTTCGAGGAGTTCAAGGGCACTGG
TAACGCTGAGCTGAAGCTGGATCGTAAGATCTCTGAGCGCCGCGTTTTCCCAGCTGTGGATGTTAATCCTTCTGGTACTC
GTAAGGATGAGCTGTTGCTCAACCCGGACGAGGCTCGCATTATGCACAAGCTGCGTCGTATTCTGTCTGCACTTGATAAT
CAGCAAGCCATTGATCTGTTGATCAAGCAGCTGAAGAAGACCAAGTCCAACGCGGAATTCCTCATGCAGGTTGCTTCCAG
CGCTCCAATGGCAGGCACAGAAAAAGAGGAGGATTACTCCTAA

Upstream 100 bases:

>100_bases
TCAATTACACAGAAGCCGAGTTCAGCCATATTTTTCGCCCGTCATATGAAAAACGGGTACATCACCGCAGCTTGGTCTGA
ACTGCAATGAAAGGAAATCT

Downstream 100 bases:

>100_bases
TGGCATCGCAGGTTTCTGCAGTTGACGATATTTTGTCGGAGTACCACGGTCTGGAACAGCAGATGGCTGATCCGGAGTTG
CACAATGATGCGGCAGCAGC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MTTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKKTSPRKAPSRTRVTQPSAPVE
QAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTPEPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENT
QGQSQGQAQGDEHDDRFESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAEQNQN
DNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDDRRSRNNRNNDRNDRNDRNDR
DNHNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDV
FVSNQLIRRMGLRSGDAIEGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRLET
EQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDERPEEVTDMQRSVNGEVIASTF
DRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGS
LTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSALDN
QQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS

Sequences:

>Translated_760_residues
MTTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKKTSPRKAPSRTRVTQPSAPVE
QAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTPEPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENT
QGQSQGQAQGDEHDDRFESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAEQNQN
DNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDDRRSRNNRNNDRNDRNDRNDR
DNHNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDV
FVSNQLIRRMGLRSGDAIEGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRLET
EQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDERPEEVTDMQRSVNGEVIASTF
DRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGS
LTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSALDN
QQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS
>Mature_759_residues
TTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKKTSPRKAPSRTRVTQPSAPVEQ
AQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTPEPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENTQ
GQSQGQAQGDEHDDRFESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAEQNQND
NSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDDRRSRNNRNNDRNDRNDRNDRD
NHNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDVF
VSNQLIRRMGLRSGDAIEGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRLETE
QKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDERPEEVTDMQRSVNGEVIASTFD
RPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGSL
TIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSALDNQ
QAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=373, Percent_Identity=55.2278820375335, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 83863; Mature: 83732

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKK
CCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCHHHCC
TSPRKAPSRTRVTQPSAPVEQAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTP
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCC
EPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENTQGQSQGQAQGDEHDDRFESR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAEQNQN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCC
DNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDD
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RRSRNNRNNDRNDRNDRNDRDNHNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNS
HHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
NDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDVFVSNQLIRRMGLRSGDAIEG
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
QVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRLET
EEEECCCCCCCCCCCCCHHHHHCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCEEEHH
EQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDER
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
PEEVTDMQRSVNGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGR
CHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
AYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTVIF
HHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCEEEE
EEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSALDN
HHHCCCCCCEEEECCHHHHCCCCCEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
QQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKK
CCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCHHHCC
TSPRKAPSRTRVTQPSAPVEQAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTP
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCC
EPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENTQGQSQGQAQGDEHDDRFESR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAEQNQN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCC
DNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDD
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RRSRNNRNNDRNDRNDRNDRDNHNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNS
HHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
NDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDVFVSNQLIRRMGLRSGDAIEG
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
QVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRLET
EEEECCCCCCCCCCCCCHHHHHCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCEEEHH
EQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDER
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
PEEVTDMQRSVNGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGR
CHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
AYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTVIF
HHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCEEEE
EEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSALDN
HHHCCCCCCEEEECCHHHHCCCCCEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
QQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]