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The map label for this gene is panE [C]

Identifier: 145295231

GI number: 145295231

Start: 1280418

End: 1281320

Strand: Direct

Name: panE [C]

Synonym: cgR_1172

Alternate gene names: 145295231

Gene position: 1280418-1281320 (Clockwise)

Preceding gene: 145295228

Following gene: 145295232

Centisome position: 38.63

GC content: 50.39

Gene sequence:

>903_bases
ATGAAAATTGCGATCGTTGGCGCTGGTGCAGTTGGTGGATATTTCGGAGCGTTGTTACAAGAATCTGGTGCAGATATCAC
GATGGTTGCACGTGGACGAACATTAGAAGCCTTGAAGTCTAAAGGACTCCACATCAACGATGCAAGAGGCGAACGCTACG
TACCAATTCCTGCAGTTGCGAGCGTGCAAGAACTAAAAGATACAGATGTAGTGATGATTGCTACTAAAGCATTATCGCTG
TCCTCAGATCTCGCTGAACTTTTGGGTGGGATACCTGCGAATTCGGTGGTCGCGATTACTCAGAATTCGATTGAAACTGC
TGATCTAGCAGCGAAGAGTATCGGTGCTGATCGTGTGTGGCCTGGTGTGGTTCGTGGGTTCTTTGTTCATGAGGGGCCAG
CCTCAGTGTCATACAAGGGAGGCCCACTGTCCTACACGTTTGGTGATTCTGGTGAACTTTCTAGGCAATTCGCAAGCACT
CTTGAACAGGCCGGTATTGACGGAGTTCTGCATCCCGATATTTTGGTGGATGTGTGGGAGAAAGCCATGTTCGTAGAGGT
TTTCGGCGGGTTGGGGGCTTTCGTCGAAAAGCAATTAGGTACCTTGCGTACGCATTTTAGGGCTTCCCTGGAAGCCTTGA
TGGAAGAGGTGGCTGAGGTGGCTCGCGCAGCAGGTGTTGCGTTGCCGAGCGATGCGGTGGAGCGCACCATGAATTTTGCG
GATCGGATGCCTGAGAATTCGACGAGTTCGATGCAGCGTGATTTGGCCGCGGGAGTGGCTAGTGAGCTTGAGGCTCAGAC
AGGTGCAATTGTGCGGGCAGCACACAAAGTGGGTGTGAAAACTCCGCTTCATGACCTTATTTATGCTGGTCTTAAGTTGA
AAGAAGAGGAAAATTCACTTTAG

Upstream 100 bases:

>100_bases
TCGTCTAATAGTGCTGCTAATCCACCGGCCATTGATGACTCCTTTATAGAGAAGGGGTAGTGCTTACAAATCTTATCTGT
GCTCAGGCAAGATAGCAGGT

Downstream 100 bases:

>100_bases
GGATAGAATCAAGATCCATGATCGTTACATCCACCGCGCGCGTTTCTATAGATCGTCCCTCGCGCTATGCCAAACAGTTA
ACTAGCCATTTGGGTGAAAA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKIAIVGAGAVGGYFGALLQESGADITMVARGRTLEALKSKGLHINDARGERYVPIPAVASVQELKDTDVVMIATKALSL
SSDLAELLGGIPANSVVAITQNSIETADLAAKSIGADRVWPGVVRGFFVHEGPASVSYKGGPLSYTFGDSGELSRQFAST
LEQAGIDGVLHPDILVDVWEKAMFVEVFGGLGAFVEKQLGTLRTHFRASLEALMEEVAEVARAAGVALPSDAVERTMNFA
DRMPENSTSSMQRDLAAGVASELEAQTGAIVRAAHKVGVKTPLHDLIYAGLKLKEEENSL

Sequences:

>Translated_300_residues
MKIAIVGAGAVGGYFGALLQESGADITMVARGRTLEALKSKGLHINDARGERYVPIPAVASVQELKDTDVVMIATKALSL
SSDLAELLGGIPANSVVAITQNSIETADLAAKSIGADRVWPGVVRGFFVHEGPASVSYKGGPLSYTFGDSGELSRQFAST
LEQAGIDGVLHPDILVDVWEKAMFVEVFGGLGAFVEKQLGTLRTHFRASLEALMEEVAEVARAAGVALPSDAVERTMNFA
DRMPENSTSSMQRDLAAGVASELEAQTGAIVRAAHKVGVKTPLHDLIYAGLKLKEEENSL
>Mature_300_residues
MKIAIVGAGAVGGYFGALLQESGADITMVARGRTLEALKSKGLHINDARGERYVPIPAVASVQELKDTDVVMIATKALSL
SSDLAELLGGIPANSVVAITQNSIETADLAAKSIGADRVWPGVVRGFFVHEGPASVSYKGGPLSYTFGDSGELSRQFAST
LEQAGIDGVLHPDILVDVWEKAMFVEVFGGLGAFVEKQLGTLRTHFRASLEALMEEVAEVARAAGVALPSDAVERTMNFA
DRMPENSTSSMQRDLAAGVASELEAQTGAIVRAAHKVGVKTPLHDLIYAGLKLKEEENSL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 31591; Mature: 31591

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVGAGAVGGYFGALLQESGADITMVARGRTLEALKSKGLHINDARGERYVPIPAVA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEECCCCCEECCCCHHH
SVQELKDTDVVMIATKALSLSSDLAELLGGIPANSVVAITQNSIETADLAAKSIGADRVW
HHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCC
PGVVRGFFVHEGPASVSYKGGPLSYTFGDSGELSRQFASTLEQAGIDGVLHPDILVDVWE
HHHHHHHHEECCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KAMFVEVFGGLGAFVEKQLGTLRTHFRASLEALMEEVAEVARAAGVALPSDAVERTMNFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
DRMPENSTSSMQRDLAAGVASELEAQTGAIVRAAHKVGVKTPLHDLIYAGLKLKEEENSL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MKIAIVGAGAVGGYFGALLQESGADITMVARGRTLEALKSKGLHINDARGERYVPIPAVA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEECCCCCEECCCCHHH
SVQELKDTDVVMIATKALSLSSDLAELLGGIPANSVVAITQNSIETADLAAKSIGADRVW
HHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCC
PGVVRGFFVHEGPASVSYKGGPLSYTFGDSGELSRQFASTLEQAGIDGVLHPDILVDVWE
HHHHHHHHEECCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KAMFVEVFGGLGAFVEKQLGTLRTHFRASLEALMEEVAEVARAAGVALPSDAVERTMNFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
DRMPENSTSSMQRDLAAGVASELEAQTGAIVRAAHKVGVKTPLHDLIYAGLKLKEEENSL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]