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The map label for this gene is ywcA [H]

Identifier: 145295002

GI number: 145295002

Start: 1046545

End: 1048200

Strand: Direct

Name: ywcA [H]

Synonym: cgR_0947

Alternate gene names: 145295002

Gene position: 1046545-1048200 (Clockwise)

Preceding gene: 145295001

Following gene: 145295003

Centisome position: 31.58

GC content: 55.31

Gene sequence:

>1656_bases
ATGAATTCCACTATTCTCCTTGCACAAGACGCTGTTTCTGAGGGCGTCGGTAATCCGATTCTTAACATCAGTGTCTTTGT
CGTCTTCATTATTGTGACGATGACCGTGGTGCTTCGCGTGGGCAAGAGCACCAGCGAATCCACTGACTTCTACACCGGTG
GTGCTTCCTTCTCTGGAACCCAGAACGGTTTGGCTATCGCAGGCGACTACCTGTCTGCAGCGTCCTTCCTCGGTATCGTT
GGTGCAATTTCACTCAACGGTTACGACGGATTCCTTTACTCCATCGGCTTCTTCGTCGCATGGCTTGTTGCACTGCTGCT
CGTGGCAGAGCCACTTCGTAACGTGGGTCGCTTCACCATGGCTGACGTGCTGTCCTTCCGCCTGCGTCAGAAGCCAGTCC
GCGTCGCTGCGGCCTGCGGTACCCTCGCGGTTACCCTCTTCTACTTGATCGCTCAGATGGCTGGTGCAGGTTCCCTCGTG
TCTGTTCTGCTTGATATCCACGAGTTCAAGTGGCAGGCAGTAGTTGTCGGTATCGTCGGCATCGTCATGATCGCCTACGT
TCTTCTTGGTGGCATGAAGGGTACCACCTACGTTCAGATGATTAAGGCAGTTCTGCTGGTCGGTGGCGTTGCCATTATGA
CCGTGCTGACCTTCGTCAAGGTGTCCGGCGGCTTAACCACCCTGCTGAACAAGGCTGTTGACACTCACGCAGCATCTGAA
TACGCGACTACCAAGGGTTACGATCCAACCCAGATCCTGGAGCCTGGCCTTCAGTACGGTGCAACTCTGACCACTCAGCT
GGACTTCATCTCCTTGGCTCTCGCTCTATGTCTTGGAACCGCTGGTCTGCCACACGTTCTGATGCGTTTCTACACCGTTC
CTACCGCTAAGGAAGCGCGTAAGTCTGTGACCTGGGCTATTGTCCTCATTGGTGCGTTCTACCTGATGACCCTGATCCTT
GGTTACGGTGCTGCGGCACTGGTTGGTCCAGACCGCGTCATTGCCGCACCAGGTGCTGCTAATGCTGCTGCTCCTCTGCT
GGCCTTCGAGCTTGGTGGTTCCATCTTCATGGCGCTAATCTCCGCAGTTGCGTTCGCTACCGTTCTCGCAGTGGTCGCAG
GTCTTGCAATTACCGCCTCTGCTGCCGTTGGCCACGACATCTACAACGCTGTTATCCGCAATGGTGAGTCCACCGAAGCA
GAGCAGGTCCGAGTATCCCGCATCACCGTTGTTGTTATCGGCCTGGTATCCATCGTCCTGGGTATTCTGGCAATGACTCA
GAACGTTGCGTTCCTCGTGGCGCTGGCCTTCGCAGTTGCAGCATCCGCAAACCTGCCAACCATCCTGTACTCCCTGTACT
GGAAGAAGTTCAACACCACCGGCGCTGTCGCCGCTATCTACACCGGCCTCATTTCCGCGCTTGTGCTGATCTTCTTGTCC
CCAGCAGTCTCCGGTAGTGACAGCGCGATGGTTCCAGGCGCAGATTGGGCAATCTTCCCACTGAAGAACCCAGGCATCGT
CTCCATCCCACTGGCATTCATCGCTGGTTGGATCGGCACCTTGGTTGGTAAGCCAGACAACATGGATGATCTTGCTGCCG
AAATGGAAGTTCGTTCTCTCACCGGTGTCGGTGTTGAAAAGGCTGTTGATCACTAA

Upstream 100 bases:

>100_bases
AACCACATTCATCATTACTTACATCTACGTCATGTTTGCGAACAAGAACTTGGAGCCTCGTCAGGCTGCTATTCGCCAGA
AGATGGAAGGTTAATCAGAT

Downstream 100 bases:

>100_bases
ATCTAGCTTCTGAAGTTACTTAAACCACCCACTCTCCAGCTGGAGGATGGGTGGTTTTCGCATGCAGTACTATTAGTGGA
CGTGTCAAGAACTTCTAAAG

Product: Na+/proline, Na+/panthothenate symporter or related permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MNSTILLAQDAVSEGVGNPILNISVFVVFIIVTMTVVLRVGKSTSESTDFYTGGASFSGTQNGLAIAGDYLSAASFLGIV
GAISLNGYDGFLYSIGFFVAWLVALLLVAEPLRNVGRFTMADVLSFRLRQKPVRVAAACGTLAVTLFYLIAQMAGAGSLV
SVLLDIHEFKWQAVVVGIVGIVMIAYVLLGGMKGTTYVQMIKAVLLVGGVAIMTVLTFVKVSGGLTTLLNKAVDTHAASE
YATTKGYDPTQILEPGLQYGATLTTQLDFISLALALCLGTAGLPHVLMRFYTVPTAKEARKSVTWAIVLIGAFYLMTLIL
GYGAAALVGPDRVIAAPGAANAAAPLLAFELGGSIFMALISAVAFATVLAVVAGLAITASAAVGHDIYNAVIRNGESTEA
EQVRVSRITVVVIGLVSIVLGILAMTQNVAFLVALAFAVAASANLPTILYSLYWKKFNTTGAVAAIYTGLISALVLIFLS
PAVSGSDSAMVPGADWAIFPLKNPGIVSIPLAFIAGWIGTLVGKPDNMDDLAAEMEVRSLTGVGVEKAVDH

Sequences:

>Translated_551_residues
MNSTILLAQDAVSEGVGNPILNISVFVVFIIVTMTVVLRVGKSTSESTDFYTGGASFSGTQNGLAIAGDYLSAASFLGIV
GAISLNGYDGFLYSIGFFVAWLVALLLVAEPLRNVGRFTMADVLSFRLRQKPVRVAAACGTLAVTLFYLIAQMAGAGSLV
SVLLDIHEFKWQAVVVGIVGIVMIAYVLLGGMKGTTYVQMIKAVLLVGGVAIMTVLTFVKVSGGLTTLLNKAVDTHAASE
YATTKGYDPTQILEPGLQYGATLTTQLDFISLALALCLGTAGLPHVLMRFYTVPTAKEARKSVTWAIVLIGAFYLMTLIL
GYGAAALVGPDRVIAAPGAANAAAPLLAFELGGSIFMALISAVAFATVLAVVAGLAITASAAVGHDIYNAVIRNGESTEA
EQVRVSRITVVVIGLVSIVLGILAMTQNVAFLVALAFAVAASANLPTILYSLYWKKFNTTGAVAAIYTGLISALVLIFLS
PAVSGSDSAMVPGADWAIFPLKNPGIVSIPLAFIAGWIGTLVGKPDNMDDLAAEMEVRSLTGVGVEKAVDH
>Mature_551_residues
MNSTILLAQDAVSEGVGNPILNISVFVVFIIVTMTVVLRVGKSTSESTDFYTGGASFSGTQNGLAIAGDYLSAASFLGIV
GAISLNGYDGFLYSIGFFVAWLVALLLVAEPLRNVGRFTMADVLSFRLRQKPVRVAAACGTLAVTLFYLIAQMAGAGSLV
SVLLDIHEFKWQAVVVGIVGIVMIAYVLLGGMKGTTYVQMIKAVLLVGGVAIMTVLTFVKVSGGLTTLLNKAVDTHAASE
YATTKGYDPTQILEPGLQYGATLTTQLDFISLALALCLGTAGLPHVLMRFYTVPTAKEARKSVTWAIVLIGAFYLMTLIL
GYGAAALVGPDRVIAAPGAANAAAPLLAFELGGSIFMALISAVAFATVLAVVAGLAITASAAVGHDIYNAVIRNGESTEA
EQVRVSRITVVVIGLVSIVLGILAMTQNVAFLVALAFAVAASANLPTILYSLYWKKFNTTGAVAAIYTGLISALVLIFLS
PAVSGSDSAMVPGADWAIFPLKNPGIVSIPLAFIAGWIGTLVGKPDNMDDLAAEMEVRSLTGVGVEKAVDH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=558, Percent_Identity=44.8028673835125, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1787251, Length=467, Percent_Identity=23.5546038543897, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57245; Mature: 57245

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCHHHHCCC
>Mature Secondary Structure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HCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]