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The map label for this gene is pbuG [H]

Identifier: 145294993

GI number: 145294993

Start: 1036304

End: 1037764

Strand: Direct

Name: pbuG [H]

Synonym: cgR_0938

Alternate gene names: 145294993

Gene position: 1036304-1037764 (Clockwise)

Preceding gene: 145294989

Following gene: 145294994

Centisome position: 31.27

GC content: 54.76

Gene sequence:

>1461_bases
ATGACGTCAGGGAAATCAACGAGTACTAGGGGAGCCCTAGACCGGTATTTCAAAATCTCGGAGCGAGGATCAAGCATTGG
CACGGAAATCCGTGCAGGTGTGGTCACATTCTTCGCGATGGCCTACATCATCATCCTCAACCCCTTGATCCTTGGCACCA
CCCCTGACGTAGAGGGTAACACCCTAGGCATCGCACAGGTTGCAGCGGCAACAGCGCTTGCCGCTGGTGTCATGACCATC
GCGTTTGGTTTGATTGCGCGTTATCCATTCGGCATTGCTGCTGGCCTGGGAATTAACACCATGGTCGCCGTGACACTGGT
TTCAGGTGAGGGCCTGACCTGGCCGGAAGCAATGGGACTTGTGGTCCTTGACGGTGTGGTCATTGTTATTTTGGCTGTGT
CCGGCTTCCGTGTTGCTGTGTTCCGTGCGATCCCAGCATCCATGAAGGCGGCCATCAGCGTGGGTATCGGCCTGTTCATC
GCCATGATCGGCCTCGTGGATGCAGGCTTTGTTCGCCGTATTCCAGATGCTGCCGGTACTACTGTGCCAGTGACCTTGGG
CATTGATGGTTCCATTGCGTCTTGGCCAACGTTCGTGTTCGTTGTCGGTGTTCTTCTCTGTGGCATCCTTGTTGTCCGTC
GAGTTCGCGGTGGACTGTTTATCGGCATTTTGGGAACCACCATTTTGGCGATCATCGCAGAAGCAATCTTTGATTCCGGT
GCGTCCTTTGAAAATGGTGAAGCAAACGCAGAAGGCTGGTCACTCGCCGTTCCTGGTCTCCCAGACTCCTTCGGTGGCAT
CCCGGATCTTTCCATCGTCGGCGCAGTAGATTTGATCGGTGCGTTCAGCCGCATCGGTGTGGTCGCCGCGACCTTGCTGA
TCTTTACCCTGGTCCTTGCAAACTTCTTCGACGCCATGGGCACCATGACCGCTCTTGGTAAGCAGGGCAACTTGGTTGAT
GATGAAGGCAACCTTCCAGACATTAAGAAGGCACTGGTTGTGGAAGGCGCAGGTGCCATTGTCGGTGGTGCTTTCTCTGC
ATCCTCCAACACCGTGTTCGCTGACTCTTCTGCAGGTGTTGCAGACGGCGCACGAACCGGCCTTGCCAACGTGGTCACCG
GCTCCTTGTTCTTGGCTGCCATGTTCTTGACCCCACTGTATGAAATCGTCCCCATCGAAGCAGCAGCACCAGTGCTCGTA
GTTGTTGGCGCGATGATGATGGGGCAGGTTACCGAGATTGATTTCTCCAAGTTCTACATCGCATTCCCAGCGTTCTTGAC
CATTGTGATCATGCCTTTCACCTACTCCATTGCAAACGGCATTGGCGTTGGATTCATCATGTACGCCATCATGGCTGCAG
CGGCAGGCAAAGCTAAGCAAGTGCACTGGCTGATGTGGCTGGTCGCTGGACTCTTCGTCGTGTTCTTCGCGATTGATCCC
ATCATGGAAGCTGTCGGCTAA

Upstream 100 bases:

>100_bases
GTTTCAGCTAAAAGAAGAATCCTTGCTAGTGGAATCAGCTGAGTTTTCCACGAGTTTTCCAGCTTTCTCACAACTTGAAT
AGAAATTGAGGTATCCGGCA

Downstream 100 bases:

>100_bases
TGACAACGCGCACGGTAATTTCTGATCCCGCAGATCCTCGTCTGGATGATGTCCGCGATCTTAACCATTCCGATTCCCGG
CCAGACCTACCCGGTGGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTSGKSTSTRGALDRYFKISERGSSIGTEIRAGVVTFFAMAYIIILNPLILGTTPDVEGNTLGIAQVAAATALAAGVMTI
AFGLIARYPFGIAAGLGINTMVAVTLVSGEGLTWPEAMGLVVLDGVVIVILAVSGFRVAVFRAIPASMKAAISVGIGLFI
AMIGLVDAGFVRRIPDAAGTTVPVTLGIDGSIASWPTFVFVVGVLLCGILVVRRVRGGLFIGILGTTILAIIAEAIFDSG
ASFENGEANAEGWSLAVPGLPDSFGGIPDLSIVGAVDLIGAFSRIGVVAATLLIFTLVLANFFDAMGTMTALGKQGNLVD
DEGNLPDIKKALVVEGAGAIVGGAFSASSNTVFADSSAGVADGARTGLANVVTGSLFLAAMFLTPLYEIVPIEAAAPVLV
VVGAMMMGQVTEIDFSKFYIAFPAFLTIVIMPFTYSIANGIGVGFIMYAIMAAAAGKAKQVHWLMWLVAGLFVVFFAIDP
IMEAVG

Sequences:

>Translated_486_residues
MTSGKSTSTRGALDRYFKISERGSSIGTEIRAGVVTFFAMAYIIILNPLILGTTPDVEGNTLGIAQVAAATALAAGVMTI
AFGLIARYPFGIAAGLGINTMVAVTLVSGEGLTWPEAMGLVVLDGVVIVILAVSGFRVAVFRAIPASMKAAISVGIGLFI
AMIGLVDAGFVRRIPDAAGTTVPVTLGIDGSIASWPTFVFVVGVLLCGILVVRRVRGGLFIGILGTTILAIIAEAIFDSG
ASFENGEANAEGWSLAVPGLPDSFGGIPDLSIVGAVDLIGAFSRIGVVAATLLIFTLVLANFFDAMGTMTALGKQGNLVD
DEGNLPDIKKALVVEGAGAIVGGAFSASSNTVFADSSAGVADGARTGLANVVTGSLFLAAMFLTPLYEIVPIEAAAPVLV
VVGAMMMGQVTEIDFSKFYIAFPAFLTIVIMPFTYSIANGIGVGFIMYAIMAAAAGKAKQVHWLMWLVAGLFVVFFAIDP
IMEAVG
>Mature_485_residues
TSGKSTSTRGALDRYFKISERGSSIGTEIRAGVVTFFAMAYIIILNPLILGTTPDVEGNTLGIAQVAAATALAAGVMTIA
FGLIARYPFGIAAGLGINTMVAVTLVSGEGLTWPEAMGLVVLDGVVIVILAVSGFRVAVFRAIPASMKAAISVGIGLFIA
MIGLVDAGFVRRIPDAAGTTVPVTLGIDGSIASWPTFVFVVGVLLCGILVVRRVRGGLFIGILGTTILAIIAEAIFDSGA
SFENGEANAEGWSLAVPGLPDSFGGIPDLSIVGAVDLIGAFSRIGVVAATLLIFTLVLANFFDAMGTMTALGKQGNLVDD
EGNLPDIKKALVVEGAGAIVGGAFSASSNTVFADSSAGVADGARTGLANVVTGSLFLAAMFLTPLYEIVPIEAAAPVLVV
VGAMMMGQVTEIDFSKFYIAFPAFLTIVIMPFTYSIANGIGVGFIMYAIMAAAAGKAKQVHWLMWLVAGLFVVFFAIDPI
MEAVG

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=470, Percent_Identity=32.1276595744681, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1790150, Length=469, Percent_Identity=33.2622601279318, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1790499, Length=477, Percent_Identity=32.9140461215933, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI48994909, Length=481, Percent_Identity=31.1850311850312, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49826; Mature: 49695

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGKSTSTRGALDRYFKISERGSSIGTEIRAGVVTFFAMAYIIILNPLILGTTPDVEGN
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TLGIAQVAAATALAAGVMTIAFGLIARYPFGIAAGLGINTMVAVTLVSGEGLTWPEAMGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHEEEEEEECCCCCCCHHHHHH
VVLDGVVIVILAVSGFRVAVFRAIPASMKAAISVGIGLFIAMIGLVDAGFVRRIPDAAGT
HHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TVPVTLGIDGSIASWPTFVFVVGVLLCGILVVRRVRGGLFIGILGTTILAIIAEAIFDSG
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCC
ASFENGEANAEGWSLAVPGLPDSFGGIPDLSIVGAVDLIGAFSRIGVVAATLLIFTLVLA
CCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFFDAMGTMTALGKQGNLVDDEGNLPDIKKALVVEGAGAIVGGAFSASSNTVFADSSAGV
HHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCCC
ADGARTGLANVVTGSLFLAAMFLTPLYEIVPIEAAAPVLVVVGAMMMGQVTEIDFSKFYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCHHHHHH
AFPAFLTIVIMPFTYSIANGIGVGFIMYAIMAAAAGKAKQVHWLMWLVAGLFVVFFAIDP
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IMEAVG
HHHHCC
>Mature Secondary Structure 
TSGKSTSTRGALDRYFKISERGSSIGTEIRAGVVTFFAMAYIIILNPLILGTTPDVEGN
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TLGIAQVAAATALAAGVMTIAFGLIARYPFGIAAGLGINTMVAVTLVSGEGLTWPEAMGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHEEEEEEECCCCCCCHHHHHH
VVLDGVVIVILAVSGFRVAVFRAIPASMKAAISVGIGLFIAMIGLVDAGFVRRIPDAAGT
HHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TVPVTLGIDGSIASWPTFVFVVGVLLCGILVVRRVRGGLFIGILGTTILAIIAEAIFDSG
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCC
ASFENGEANAEGWSLAVPGLPDSFGGIPDLSIVGAVDLIGAFSRIGVVAATLLIFTLVLA
CCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFFDAMGTMTALGKQGNLVDDEGNLPDIKKALVVEGAGAIVGGAFSASSNTVFADSSAGV
HHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCCC
ADGARTGLANVVTGSLFLAAMFLTPLYEIVPIEAAAPVLVVVGAMMMGQVTEIDFSKFYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCHHHHHH
AFPAFLTIVIMPFTYSIANGIGVGFIMYAIMAAAAGKAKQVHWLMWLVAGLFVVFFAIDP
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IMEAVG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]