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The map label for this gene is suhB [H]

Identifier: 145294960

GI number: 145294960

Start: 999168

End: 1000034

Strand: Reverse

Name: suhB [H]

Synonym: cgR_0905

Alternate gene names: 145294960

Gene position: 1000034-999168 (Counterclockwise)

Preceding gene: 145294966

Following gene: 145294959

Centisome position: 30.17

GC content: 59.75

Gene sequence:

>867_bases
ATGACTAATCCAGAGCAGACACATCCCGCTGCAAGCCTCGAAGACATGATCAAAACCATCACAAAGACCTTCGTGATTGC
TCACGATCAGGATTCTGATGAGCATCTTGCGCAGGCACTGGTGTACAACGCTGGACGTTTGGCGTGGCGCATGCGCGAAA
ACGGTGTGGATACGGATTACAAGACTTCTGTGTCTGATGTGGTCACGGATGCCGATCGTGCGGCCGAGGCCTTCGTCGCA
GGAGTTCTTGAAGCGTTGCGGCCGGAGGACGGCGTGCTTGGCGAGGAAGGCGCGGACCGGGCGTCGAAAAGCGGAAAAAC
CTGGGTCATCGACCCGGTTGATGGCACCTACAACTTCACCCAGGGCTCAGATTATTGGTGCTCGGCGCTCGCGCTGGTCG
AGGGCGATCCATCCGCGCCATCGCGCGTGCTTTTCGGCGCCGTACACCGCCCAGCCATGGGTTATACGTGGTTCGGTGGC
CCGGGAATCCGCACCACGCTCGACGGCAAGGAGCTAGATTTGCTTGTCGACGCCCCCCTCAATCAAATCTCCCTGGCCAC
CTACATCCACCCGTCACGCATCGCGGAACCTGATATTCAAAAGGCGTGGATGAGCGTTGCCACCCACCCTGCAACGCTGC
GCATGTTCGGCGCCGGCTCCATCGATTTGGCCAACATCGCCGACGGCAGCATCGGCGCATGGGTGCAGCACAGCGTCGCA
GATTGGGACTGGCTACCCGGCCGCGCACTCATCGAAGGCGTCGGCGGAGCATGCATCAAAGTGACCGCCGGCGGCGTCGA
ATGGTCCGTTGCAGGAAACGCGGAAGCAGTTAGTGAGATCTCCGAAACTTTAAGCGCACTAGACTAA

Upstream 100 bases:

>100_bases
ATTCGGGACGCATGATTGCACATATTACCCGCACCGATTGTGATTCTTAGAACGCCACCTTATTCAGCACACTTGGCCGA
CGGCATGCACAATGGAAGAC

Downstream 100 bases:

>100_bases
CAACACATGAGCAAATATGCAGACGATTTAGCCTTAGCCCTCGAACTCGCCGAACTTGCCGATTCCATCACCCTCGACCG
CTTCGAAGCCTCTGACCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWRMRENGVDTDYKTSVSDVVTDADRAAEAFVA
GVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGG
PGIRTTLDGKELDLLVDAPLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQHSVA
DWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD

Sequences:

>Translated_288_residues
MTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWRMRENGVDTDYKTSVSDVVTDADRAAEAFVA
GVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGG
PGIRTTLDGKELDLLVDAPLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQHSVA
DWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD
>Mature_287_residues
TNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWRMRENGVDTDYKTSVSDVVTDADRAAEAFVAG
VLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGGP
GIRTTLDGKELDLLVDAPLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQHSVAD
WDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=238, Percent_Identity=22.6890756302521, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=23.6286919831224, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI221625487, Length=238, Percent_Identity=22.6890756302521, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788882, Length=211, Percent_Identity=25.1184834123223, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357329, Length=279, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24664926, Length=227, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664922, Length=233, Percent_Identity=24.0343347639485, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357303, Length=266, Percent_Identity=27.0676691729323, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 30695; Mature: 30564

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWRMRENGVDTDY
CCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCHHEEEECCCCCCCCH
KTSVSDVVTDADRAAEAFVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFT
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCEECC
QGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGGPGIRTTLDGKELDLLVDAPL
CCCCHHEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEECCCEEEEEECCCC
NQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQHSVA
CCEEEEEEECHHHCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCCHHHHHCCC
DWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD
CCCCCCCHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWRMRENGVDTDY
CCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCHHEEEECCCCCCCCH
KTSVSDVVTDADRAAEAFVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFT
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCEECC
QGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGGPGIRTTLDGKELDLLVDAPL
CCCCHHEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEECCCEEEEEECCCC
NQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQHSVA
CCEEEEEEECHHHCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCCHHHHHCCC
DWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD
CCCCCCCHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]