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The map label for this gene is alsR [H]

Identifier: 145294576

GI number: 145294576

Start: 587040

End: 587921

Strand: Reverse

Name: alsR [H]

Synonym: cgR_0527

Alternate gene names: 145294576

Gene position: 587921-587040 (Counterclockwise)

Preceding gene: 145294577

Following gene: 145294575

Centisome position: 17.74

GC content: 51.13

Gene sequence:

>882_bases
TTGTTCACTCTTGAACAGTTGCGGTGTTTCGTCGCCGTCGCCAATCATCTTCATTTCGGTAAAGCTGCTGCAGAGCTATC
CATGACACAGCCACCGTTGAGTCGTCAGATTCAAAAGCTGGAGAAGATCGTCGGTGCAACCCTGCTTGATCGTGACAACC
GCAAGGTGGAATTGACCACTGCGGGTCTCGCATTTTTGAAAGATGCACGCCTCATTCTCAATTCCACCGAGAAGGCGGCT
GAGCGTGCGCGATTGGCCAGTTCTGGCATGTGGGGACAGCTCAATATTGGATATACCGCGGCTGCGGGTTTTTCCATTTT
GGGTCCGACCTTGAATCAGCTGCATGAGAAGATGCCGGGTGTGAGCGTCGATCTTTTTGAGATGGTCTCCACCGAACAGG
TCGATGCCTTGGAGTCTGGGCTGTTAGATCTTGGCATTGGCCGATTGAGCTCGCCAGTTGAGGGGCTTCAAACTCGACGT
CTCCAGGCGGATTCTCTGGTTCTTGCAGCGCCGAAAGGACATCCACTTCTTGATCAGAATCGACCACTGTTGCGAAAGCA
TCTGACTGGGGTTCCTTTTCTGCAGCACTCTCCCACCAAGGCGAAGTACCTCTATGACATCGTTGTTAGAAACTTCACGA
TCAATGATGCGCAGGTGCAACATACGCTGAGCCAGATCACCACGATGGTTAGTCTGGTGGCCTCTGGACTGGGTGTTGCG
CTGGTTCCGGAGTCTGCGAAAAAACTCAATTACAGCGGTGTTGAGTATCGCCATTTTTATGATCTACCTGTTGGCTTAGC
GGAGCTTCAGGCTATTTATTCCACCTCGAATGATAATCCTGCGTTGCGGAGATTCATCAAGAACATTGACGATACCTTTT
AG

Upstream 100 bases:

>100_bases
CGTTCACAGCCAGCCACCTGAGGACGAGGACATCGATCGCATTCAGAAAAAGCTGCAGGCCGAGGGCTTCCCCACCCGCA
ATTAAATAATTGGAGTTTTG

Downstream 100 bases:

>100_bases
GCATTTCAGCATGCCAAACTAATCTTGGACAGGTATCACTGGCTCCTCTTAGACTCCAAAGTGTCTTTGAAAACACTCAC
CCAAGGAGCCCTCATGGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MFTLEQLRCFVAVANHLHFGKAAAELSMTQPPLSRQIQKLEKIVGATLLDRDNRKVELTTAGLAFLKDARLILNSTEKAA
ERARLASSGMWGQLNIGYTAAAGFSILGPTLNQLHEKMPGVSVDLFEMVSTEQVDALESGLLDLGIGRLSSPVEGLQTRR
LQADSLVLAAPKGHPLLDQNRPLLRKHLTGVPFLQHSPTKAKYLYDIVVRNFTINDAQVQHTLSQITTMVSLVASGLGVA
LVPESAKKLNYSGVEYRHFYDLPVGLAELQAIYSTSNDNPALRRFIKNIDDTF

Sequences:

>Translated_293_residues
MFTLEQLRCFVAVANHLHFGKAAAELSMTQPPLSRQIQKLEKIVGATLLDRDNRKVELTTAGLAFLKDARLILNSTEKAA
ERARLASSGMWGQLNIGYTAAAGFSILGPTLNQLHEKMPGVSVDLFEMVSTEQVDALESGLLDLGIGRLSSPVEGLQTRR
LQADSLVLAAPKGHPLLDQNRPLLRKHLTGVPFLQHSPTKAKYLYDIVVRNFTINDAQVQHTLSQITTMVSLVASGLGVA
LVPESAKKLNYSGVEYRHFYDLPVGLAELQAIYSTSNDNPALRRFIKNIDDTF
>Mature_293_residues
MFTLEQLRCFVAVANHLHFGKAAAELSMTQPPLSRQIQKLEKIVGATLLDRDNRKVELTTAGLAFLKDARLILNSTEKAA
ERARLASSGMWGQLNIGYTAAAGFSILGPTLNQLHEKMPGVSVDLFEMVSTEQVDALESGLLDLGIGRLSSPVEGLQTRR
LQADSLVLAAPKGHPLLDQNRPLLRKHLTGVPFLQHSPTKAKYLYDIVVRNFTINDAQVQHTLSQITTMVSLVASGLGVA
LVPESAKKLNYSGVEYRHFYDLPVGLAELQAIYSTSNDNPALRRFIKNIDDTF

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=35.3951890034364, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=34.5890410958904, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI2367136, Length=296, Percent_Identity=30.4054054054054, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790399, Length=250, Percent_Identity=28.8, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081904, Length=184, Percent_Identity=31.5217391304348, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790208, Length=243, Percent_Identity=29.2181069958848, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=34.965034965035, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=255, Percent_Identity=25.0980392156863, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI157672245, Length=169, Percent_Identity=31.9526627218935, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789173, Length=246, Percent_Identity=28.8617886178862, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787949, Length=247, Percent_Identity=25.5060728744939, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=23.5772357723577, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788626, Length=143, Percent_Identity=34.965034965035, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32175; Mature: 32175

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLEQLRCFVAVANHLHFGKAAAELSMTQPPLSRQIQKLEKIVGATLLDRDNRKVELTT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEH
AGLAFLKDARLILNSTEKAAERARLASSGMWGQLNIGYTAAAGFSILGPTLNQLHEKMPG
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCEEHHCCCHHHCHHHHHHHHHCCC
VSVDLFEMVSTEQVDALESGLLDLGIGRLSSPVEGLQTRRLQADSLVLAAPKGHPLLDQN
CCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCC
RPLLRKHLTGVPFLQHSPTKAKYLYDIVVRNFTINDAQVQHTLSQITTMVSLVASGLGVA
CHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
LVPESAKKLNYSGVEYRHFYDLPVGLAELQAIYSTSNDNPALRRFIKNIDDTF
EECCHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTLEQLRCFVAVANHLHFGKAAAELSMTQPPLSRQIQKLEKIVGATLLDRDNRKVELTT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEH
AGLAFLKDARLILNSTEKAAERARLASSGMWGQLNIGYTAAAGFSILGPTLNQLHEKMPG
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCEEHHCCCHHHCHHHHHHHHHCCC
VSVDLFEMVSTEQVDALESGLLDLGIGRLSSPVEGLQTRRLQADSLVLAAPKGHPLLDQN
CCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCC
RPLLRKHLTGVPFLQHSPTKAKYLYDIVVRNFTINDAQVQHTLSQITTMVSLVASGLGVA
CHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
LVPESAKKLNYSGVEYRHFYDLPVGLAELQAIYSTSNDNPALRRFIKNIDDTF
EECCHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]