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The map label for this gene is ykoH [H]

Identifier: 145294405

GI number: 145294405

Start: 394944

End: 396413

Strand: Reverse

Name: ykoH [H]

Synonym: cgR_0360

Alternate gene names: 145294405

Gene position: 396413-394944 (Counterclockwise)

Preceding gene: 145294406

Following gene: 145294404

Centisome position: 11.96

GC content: 53.88

Gene sequence:

>1470_bases
ATGGCTAAATCAACTCCTTTGAGTGCATCGCTGCGCTGGCGAATTGTCCTGTGGATGACAGCGGTTGTTTTCTTGACCCT
GGCCAGCGTTGTGATCATTACCCGTTCGGTGCTGCTTTCAGAGGTAACCAACACCGCGAACTCGGCAGTTGAGCAGGAAA
TTGAGGAGTTTCGTCGCTTTGCAGCCGAAGGAATTGATCCAACAACTGCGCAGCCTTTTGAGTCAGGTCATCGCCTGATG
GAGGTTTACCTGTCGAGGCAGATTCCGGATGAAAATGAAGCCATTGTCGGCATTTTCCCCGGAGAGCTCATCCAGGTTGA
TTACTCCCAGCTCAGTGGCGCCCATCCGCTTCCTTTGGAACACTCCGATCCGTTGATTTCGGAAATCCGACAGACCACGC
TGAATTCTGGAGTTTTCAGCGATCTTGAACGCGGAACCACTCACTGGGGCAAGGTGAATTTCCAAACTGCTTCCGGTGAG
GCCGATGGTGAATTCGTTGTCGCATTCTTCGCTGATAATCTTAAAGACCAGGTCAACGGCCAGATCCAGATTCTAATTTT
GATCGGCACAGGGGGTTTGATTGCCTCAATTCTGATTGCTTGGTTGATTGCAGGCCAGATCATTGCCCCGATCCGCAAAT
TGAGTTCCGTGTCCGCAAAGATCAGTAATTCGGATCTCACCTGGCGCGTCCCTGTGGAGGGTCGTGATGAGATTGCGCAG
CTGGCCAGGACTTTCAATGCCATGTTGGATCGCATCGAAATCGCGTATAACGATCAGCGCCAGTTCGTTGATGATGCCGG
CCATGAGCTGCGCACCCCGATCACAGTGGTGCGTGGCCAGTTAGAGCTTCTCGCCACCACCCCGCCGGAGGAACAAGCGC
GGTCGATTGAGCTGGCCACCACTGAGTTGGATCGAATGTCGCGAATGGTCAATGATCTGCTCACCCTCGCAGTCGCCGAT
TCCGGCACCTTCATCCACGCCCACCCCACGGATGTCACAGACTTAACCATCGATATCGAAGACAAAGCCCGCACCATCAG
CGACCGAATTTTGCTTGTCGACGCCGCCGAGGGCCTCGTCAGCCTCGACGAGCAGCGGGTCACCGAGGCAGTGCTGGAGT
TGTTCGGCAATGCGTTGCGCTACAGCGATGATGTGGTGGAGTTGGGTTCAGATTTCAGGGGGTCTGGCCCCGACCGCGTT
TTTCGCATTTGGGTTCGTGACAAAGGAAACGGTGTTGATATGGATGAACAAGAAGCCCTGTTCGATCGCTTCTCCAGAGG
CTCCCAAAAAAATTCACGGCGTCCCGGTGGCGCCGGCCTAGGCTTATCTATTGTCAAAGCAATCGGCGAGGCCCATGGTG
GCCGAGCTTTCGTTAATTCAACACCAGGTTTAGGTTCCATTTTCGGACTAGAAATTCCCGCACCACAACAATCAAAGGAA
TACACCCATGAGCAAGATCCTGCTCGCTGA

Upstream 100 bases:

>100_bases
AAATTCCTCAAGCCCCACAAGTTCCACTCAATTATCAGTACTATGACGATGACTGGGACGACGATGACGACTAACTAACC
CCTGAGGCACTTTCTATTTC

Downstream 100 bases:

>100_bases
AGATGACGCCGGCATCGCAGATTTCATCGTTCGTGGCCTCATCCGCGAAGGCTTCGAATGCGAGATCACCGAATCCGGAG
CCGAAGCTTTCGCCCGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MAKSTPLSASLRWRIVLWMTAVVFLTLASVVIITRSVLLSEVTNTANSAVEQEIEEFRRFAAEGIDPTTAQPFESGHRLM
EVYLSRQIPDENEAIVGIFPGELIQVDYSQLSGAHPLPLEHSDPLISEIRQTTLNSGVFSDLERGTTHWGKVNFQTASGE
ADGEFVVAFFADNLKDQVNGQIQILILIGTGGLIASILIAWLIAGQIIAPIRKLSSVSAKISNSDLTWRVPVEGRDEIAQ
LARTFNAMLDRIEIAYNDQRQFVDDAGHELRTPITVVRGQLELLATTPPEEQARSIELATTELDRMSRMVNDLLTLAVAD
SGTFIHAHPTDVTDLTIDIEDKARTISDRILLVDAAEGLVSLDEQRVTEAVLELFGNALRYSDDVVELGSDFRGSGPDRV
FRIWVRDKGNGVDMDEQEALFDRFSRGSQKNSRRPGGAGLGLSIVKAIGEAHGGRAFVNSTPGLGSIFGLEIPAPQQSKE
YTHEQDPAR

Sequences:

>Translated_489_residues
MAKSTPLSASLRWRIVLWMTAVVFLTLASVVIITRSVLLSEVTNTANSAVEQEIEEFRRFAAEGIDPTTAQPFESGHRLM
EVYLSRQIPDENEAIVGIFPGELIQVDYSQLSGAHPLPLEHSDPLISEIRQTTLNSGVFSDLERGTTHWGKVNFQTASGE
ADGEFVVAFFADNLKDQVNGQIQILILIGTGGLIASILIAWLIAGQIIAPIRKLSSVSAKISNSDLTWRVPVEGRDEIAQ
LARTFNAMLDRIEIAYNDQRQFVDDAGHELRTPITVVRGQLELLATTPPEEQARSIELATTELDRMSRMVNDLLTLAVAD
SGTFIHAHPTDVTDLTIDIEDKARTISDRILLVDAAEGLVSLDEQRVTEAVLELFGNALRYSDDVVELGSDFRGSGPDRV
FRIWVRDKGNGVDMDEQEALFDRFSRGSQKNSRRPGGAGLGLSIVKAIGEAHGGRAFVNSTPGLGSIFGLEIPAPQQSKE
YTHEQDPAR
>Mature_488_residues
AKSTPLSASLRWRIVLWMTAVVFLTLASVVIITRSVLLSEVTNTANSAVEQEIEEFRRFAAEGIDPTTAQPFESGHRLME
VYLSRQIPDENEAIVGIFPGELIQVDYSQLSGAHPLPLEHSDPLISEIRQTTLNSGVFSDLERGTTHWGKVNFQTASGEA
DGEFVVAFFADNLKDQVNGQIQILILIGTGGLIASILIAWLIAGQIIAPIRKLSSVSAKISNSDLTWRVPVEGRDEIAQL
ARTFNAMLDRIEIAYNDQRQFVDDAGHELRTPITVVRGQLELLATTPPEEQARSIELATTELDRMSRMVNDLLTLAVADS
GTFIHAHPTDVTDLTIDIEDKARTISDRILLVDAAEGLVSLDEQRVTEAVLELFGNALRYSDDVVELGSDFRGSGPDRVF
RIWVRDKGNGVDMDEQEALFDRFSRGSQKNSRRPGGAGLGLSIVKAIGEAHGGRAFVNSTPGLGSIFGLEIPAPQQSKEY
THEQDPAR

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=29.7491039426523, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786783, Length=347, Percent_Identity=27.9538904899135, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=31.6742081447964, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=280, Percent_Identity=26.7857142857143, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788279, Length=299, Percent_Identity=29.7658862876254, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790346, Length=259, Percent_Identity=27.7992277992278, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=316, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=24.1071428571429, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789403, Length=290, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787374, Length=497, Percent_Identity=22.9376257545272, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=26.4957264957265, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53625; Mature: 53494

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSTPLSASLRWRIVLWMTAVVFLTLASVVIITRSVLLSEVTNTANSAVEQEIEEFRRF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEGIDPTTAQPFESGHRLMEVYLSRQIPDENEAIVGIFPGELIQVDYSQLSGAHPLPLE
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHCCCCCCCCCC
HSDPLISEIRQTTLNSGVFSDLERGTTHWGKVNFQTASGEADGEFVVAFFADNLKDQVNG
CCCHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCHHHHCCC
QIQILILIGTGGLIASILIAWLIAGQIIAPIRKLSSVSAKISNSDLTWRVPVEGRDEIAQ
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCHHHHHH
LARTFNAMLDRIEIAYNDQRQFVDDAGHELRTPITVVRGQLELLATTPPEEQARSIELAT
HHHHHHHHHHHHHHEECCHHHHHHHCCHHHCCCHHHHHCCEEEEECCCCHHHHCEEEHHH
TELDRMSRMVNDLLTLAVADSGTFIHAHPTDVTDLTIDIEDKARTISDRILLVDAAEGLV
HHHHHHHHHHHHHHHHEEECCCCEEEECCCCCEEEEEEECHHHHHHCCEEEEEECCCHHH
SLDEQRVTEAVLELFGNALRYSDDVVELGSDFRGSGPDRVFRIWVRDKGNGVDMDEQEAL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHH
FDRFSRGSQKNSRRPGGAGLGLSIVKAIGEAHGGRAFVNSTPGLGSIFGLEIPAPQQSKE
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCHH
YTHEQDPAR
CCCCCCCCC
>Mature Secondary Structure 
AKSTPLSASLRWRIVLWMTAVVFLTLASVVIITRSVLLSEVTNTANSAVEQEIEEFRRF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEGIDPTTAQPFESGHRLMEVYLSRQIPDENEAIVGIFPGELIQVDYSQLSGAHPLPLE
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHCCCCCCCCCC
HSDPLISEIRQTTLNSGVFSDLERGTTHWGKVNFQTASGEADGEFVVAFFADNLKDQVNG
CCCHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCHHHHCCC
QIQILILIGTGGLIASILIAWLIAGQIIAPIRKLSSVSAKISNSDLTWRVPVEGRDEIAQ
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCHHHHHH
LARTFNAMLDRIEIAYNDQRQFVDDAGHELRTPITVVRGQLELLATTPPEEQARSIELAT
HHHHHHHHHHHHHHEECCHHHHHHHCCHHHCCCHHHHHCCEEEEECCCCHHHHCEEEHHH
TELDRMSRMVNDLLTLAVADSGTFIHAHPTDVTDLTIDIEDKARTISDRILLVDAAEGLV
HHHHHHHHHHHHHHHHEEECCCCEEEECCCCCEEEEEEECHHHHHHCCEEEEEECCCHHH
SLDEQRVTEAVLELFGNALRYSDDVVELGSDFRGSGPDRVFRIWVRDKGNGVDMDEQEAL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHH
FDRFSRGSQKNSRRPGGAGLGLSIVKAIGEAHGGRAFVNSTPGLGSIFGLEIPAPQQSKE
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCHH
YTHEQDPAR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]