Click here to switch to the map view.

The map label for this gene is tcrA [H]

Identifier: 145294404

GI number: 145294404

Start: 394298

End: 394966

Strand: Reverse

Name: tcrA [H]

Synonym: cgR_0359

Alternate gene names: 145294404

Gene position: 394966-394298 (Counterclockwise)

Preceding gene: 145294405

Following gene: 145294402

Centisome position: 11.92

GC content: 53.66

Gene sequence:

>669_bases
ATGAGCAAGATCCTGCTCGCTGAAGATGACGCCGGCATCGCAGATTTCATCGTTCGTGGCCTCATCCGCGAAGGCTTCGA
ATGCGAGATCACCGAATCCGGAGCCGAAGCTTTCGCCCGCGCCCATTCCGGCGATTTCGATCTCATGGTTTTAGACCTCG
GCCTTCCACACATGGACGGCACGGATATCCTAGAGCAATTAAGAAATCTGCAGGTCACGCTACCTATCATTGTGCTCACG
GCACGCACCAACATTGAGGATCGTCTCCGCACCCTTGAGGGAGGCGCTGATGATTATATGCCCAAGCCGTTTCAATTCGC
TGAGCTTTTAGCGCGCATCAAACTTCGTCTTGCCAAACATACTGCTCAAGAATCGCCGACCGATGCACGTGTGCTGCGCA
ACGGCGATGTCGAGCTTGATCTTCGTACCCAGCGCGTGCTTATCGACGGCTCCTGGCACGATCTTTCCCGGCGCGAAGTA
GATCTCTTAGAAACTCTCATGCGTCACCCAGGACAGATTCTCTCCCGCGCGCAGCTTCTCCGGTTGGTGTGGGATATGGA
TTGGGATCCTGGATCGAATGTCGTCGATGTATATGTGCGTGCATTACGGAAGAAAATTGGGGCGCACCGAATTGAAACTG
TTCGCGGTTCTGGTTACAGATTGAGATAA

Upstream 100 bases:

>100_bases
GAGGCCCATGGTGGCCGAGCTTTCGTTAATTCAACACCAGGTTTAGGTTCCATTTTCGGACTAGAAATTCCCGCACCACA
ACAATCAAAGGAATACACCC

Downstream 100 bases:

>100_bases
CATTTTGGATCAATGCGTTTTCGCATGAATGATTACTAATTGGACGTAGTCGATAGATCACTATTCTCATAATCTGTGAG
CATGACCACTTCAACTATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSKILLAEDDAGIADFIVRGLIREGFECEITESGAEAFARAHSGDFDLMVLDLGLPHMDGTDILEQLRNLQVTLPIIVLT
ARTNIEDRLRTLEGGADDYMPKPFQFAELLARIKLRLAKHTAQESPTDARVLRNGDVELDLRTQRVLIDGSWHDLSRREV
DLLETLMRHPGQILSRAQLLRLVWDMDWDPGSNVVDVYVRALRKKIGAHRIETVRGSGYRLR

Sequences:

>Translated_222_residues
MSKILLAEDDAGIADFIVRGLIREGFECEITESGAEAFARAHSGDFDLMVLDLGLPHMDGTDILEQLRNLQVTLPIIVLT
ARTNIEDRLRTLEGGADDYMPKPFQFAELLARIKLRLAKHTAQESPTDARVLRNGDVELDLRTQRVLIDGSWHDLSRREV
DLLETLMRHPGQILSRAQLLRLVWDMDWDPGSNVVDVYVRALRKKIGAHRIETVRGSGYRLR
>Mature_221_residues
SKILLAEDDAGIADFIVRGLIREGFECEITESGAEAFARAHSGDFDLMVLDLGLPHMDGTDILEQLRNLQVTLPIIVLTA
RTNIEDRLRTLEGGADDYMPKPFQFAELLARIKLRLAKHTAQESPTDARVLRNGDVELDLRTQRVLIDGSWHDLSRREVD
LLETLMRHPGQILSRAQLLRLVWDMDWDPGSNVVDVYVRALRKKIGAHRIETVRGSGYRLR

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=39.0134529147982, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=40, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=36.322869955157, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=36.0730593607306, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=38.3561643835616, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=35.5263157894737, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=33.7719298245614, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=36.1233480176211, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=31.2217194570136, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=34.8936170212766, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=30.7017543859649, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=32.8888888888889, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.8245614035088, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790299, Length=128, Percent_Identity=28.90625, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=127, Percent_Identity=29.9212598425197, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=30.3571428571429, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25177; Mature: 25046

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILLAEDDAGIADFIVRGLIREGFECEITESGAEAFARAHSGDFDLMVLDLGLPHMDG
CCCEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCEEEEEECCCCCCCC
TDILEQLRNLQVTLPIIVLTARTNIEDRLRTLEGGADDYMPKPFQFAELLARIKLRLAKH
HHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TAQESPTDARVLRNGDVELDLRTQRVLIDGSWHDLSRREVDLLETLMRHPGQILSRAQLL
HHCCCCCHHHHHCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
RLVWDMDWDPGSNVVDVYVRALRKKIGAHRIETVRGSGYRLR
HHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKILLAEDDAGIADFIVRGLIREGFECEITESGAEAFARAHSGDFDLMVLDLGLPHMDG
CCEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCEEEEEECCCCCCCC
TDILEQLRNLQVTLPIIVLTARTNIEDRLRTLEGGADDYMPKPFQFAELLARIKLRLAKH
HHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TAQESPTDARVLRNGDVELDLRTQRVLIDGSWHDLSRREVDLLETLMRHPGQILSRAQLL
HHCCCCCHHHHHCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
RLVWDMDWDPGSNVVDVYVRALRKKIGAHRIETVRGSGYRLR
HHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]