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The map label for this gene is baeS [H]

Identifier: 145294165

GI number: 145294165

Start: 142991

End: 144190

Strand: Direct

Name: baeS [H]

Synonym: cgR_0123

Alternate gene names: 145294165

Gene position: 142991-144190 (Clockwise)

Preceding gene: 145294164

Following gene: 145294166

Centisome position: 4.31

GC content: 65.08

Gene sequence:

>1200_bases
ATGAATCACGGACCCGGCCTGACCTTCCGCTTCCTGACCGCCCAGGTGTTGGTCGTGGTGATTAGCCTGCTGGTGGCCGC
GGCCGTGGCCACGATGGTGGGCCCGACCCTGTTCCATGATCATATGTTGATGACCGGCCGGGAGGACCCCTCGCTGGAGC
TGTTCCATGCCGAGCAGGCCTACCGGGACGCCAACCTGATCACCCTGGCCGTCGCCCTGCCCACCGCCTTGATCAGCGCC
CTGCTGGCCAGCCTGTGGTTATCGCGTCGCCTGCGCACCCCCCTGCAGGATCTCACCCGCGCCGCTACCAGCCTGACGGC
CGGCAACTACCGTATCCGCGTGCCCGCCGGAGAAGCAGGCCCCGAGGTCACCACCCTGGCGCATGCCTTCAACACCATGG
CCGACCGGCTGGAACACACCGAACAGGTCCGCCGCCAGATGCTCTCTGATCTGGCCCACGAAATGGGCACCCCCTTATCG
GTGCTCACGGTCTACTTCGATGGTCTCCAGGACGGGGTCGTGGACTGGAATAATGCCACCCACACGATCATGGCTGACCA
ACTCACCCGCCTGACCCGGTTGATGGAAGACATCGACGATGTCTCCCGGGCCCAGGAACACCGGATCGATTTGGACCTGG
CGGAGGAAGGGCTCGGGGATCTGCTCCATACCGCCGCTGCTGCCGCGGGGGAAGCTTATGCTGACAAAGGCGTCGATTTA
CAGGTCGAGACCATTACGGACACCGTCCGGGTGCTCGTGGACCGGCAACGCTTCGGCCAGGTGATGAGCAATCTCCTGTC
GAACGCGCTACGGCACACCCCGGCCGGCGGGCAGGTCCGGATCAGCGTCCGCCGACAGGGGGCGTCCACCGCGCTCATCC
ACGTCGCCGATGACGGCGAGGGCATCCCACCTGGCCAGCTCGGACACATCTTCGAACGCTTCTACCGGGGGGATGCCGCC
CGCAGCCGGGACAACGGCGGGGCCGGTATCGGTCTGACCATCTCCAAGGCATTGATCGAGGCCCACGGCGGCACTCTCAC
CGCCACCTCTCCTGGCCCCGGTGCCGGATCGGTCTTCACCATCCGTCTTCCCCTGCACCAGGAAAACGTGTCCCTGATGC
TCGGTGACCCCACTCCCGGGGACAATAATTCTGATGACCTCGGCAGCGATCCGTATCAACCCCTTGACAATACCCCATAG

Upstream 100 bases:

>100_bases
ATGTCCACATCGGCAACTTGCGTCGCAAGCTCGGCACCGACACCCGGGGCCGGGGGTTTATCGACACCGTGCGTGGCGTG
GGCTACCGGGTGGGGCAGCC

Downstream 100 bases:

>100_bases
GGGTATACGATGGGAGGGGAAACCCCGCCTGATCCCCCGATCCCACAGGAGCGATCCGATGACCACCCCGACTTCCCCCT
TGCTGCCGCTGGCCTCCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNHGPGLTFRFLTAQVLVVVISLLVAAAVATMVGPTLFHDHMLMTGREDPSLELFHAEQAYRDANLITLAVALPTALISA
LLASLWLSRRLRTPLQDLTRAATSLTAGNYRIRVPAGEAGPEVTTLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLS
VLTVYFDGLQDGVVDWNNATHTIMADQLTRLTRLMEDIDDVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
QVETITDTVRVLVDRQRFGQVMSNLLSNALRHTPAGGQVRISVRRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAA
RSRDNGGAGIGLTISKALIEAHGGTLTATSPGPGAGSVFTIRLPLHQENVSLMLGDPTPGDNNSDDLGSDPYQPLDNTP

Sequences:

>Translated_399_residues
MNHGPGLTFRFLTAQVLVVVISLLVAAAVATMVGPTLFHDHMLMTGREDPSLELFHAEQAYRDANLITLAVALPTALISA
LLASLWLSRRLRTPLQDLTRAATSLTAGNYRIRVPAGEAGPEVTTLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLS
VLTVYFDGLQDGVVDWNNATHTIMADQLTRLTRLMEDIDDVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
QVETITDTVRVLVDRQRFGQVMSNLLSNALRHTPAGGQVRISVRRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAA
RSRDNGGAGIGLTISKALIEAHGGTLTATSPGPGAGSVFTIRLPLHQENVSLMLGDPTPGDNNSDDLGSDPYQPLDNTP
>Mature_399_residues
MNHGPGLTFRFLTAQVLVVVISLLVAAAVATMVGPTLFHDHMLMTGREDPSLELFHAEQAYRDANLITLAVALPTALISA
LLASLWLSRRLRTPLQDLTRAATSLTAGNYRIRVPAGEAGPEVTTLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLS
VLTVYFDGLQDGVVDWNNATHTIMADQLTRLTRLMEDIDDVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
QVETITDTVRVLVDRQRFGQVMSNLLSNALRHTPAGGQVRISVRRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAA
RSRDNGGAGIGLTISKALIEAHGGTLTATSPGPGAGSVFTIRLPLHQENVSLMLGDPTPGDNNSDDLGSDPYQPLDNTP

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=281, Percent_Identity=35.9430604982206, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786783, Length=286, Percent_Identity=29.7202797202797, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787894, Length=303, Percent_Identity=30.03300330033, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=29.3906810035842, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=29.5546558704453, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=30.4347826086957, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=113, Percent_Identity=46.0176991150442, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788279, Length=299, Percent_Identity=26.7558528428094, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=269, Percent_Identity=26.3940520446097, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=30, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=247, Percent_Identity=25.5060728744939, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=27.9850746268657, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=27.4336283185841, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=298, Percent_Identity=25.8389261744966, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=316, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=302, Percent_Identity=28.8079470198675, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=24.5733788395904, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=291, Percent_Identity=28.5223367697594, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42873; Mature: 42873

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHGPGLTFRFLTAQVLVVVISLLVAAAVATMVGPTLFHDHMLMTGREDPSLELFHAEQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCEEEEEHHHH
YRDANLITLAVALPTALISALLASLWLSRRLRTPLQDLTRAATSLTAGNYRIRVPAGEAG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCC
PEVTTLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLSVLTVYFDGLQDGVVDWNNAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
HTIMADQLTRLTRLMEDIDDVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
QVETITDTVRVLVDRQRFGQVMSNLLSNALRHTPAGGQVRISVRRQGASTALIHVADDGE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCC
GIPPGQLGHIFERFYRGDAARSRDNGGAGIGLTISKALIEAHGGTLTATSPGPGAGSVFT
CCCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCCEEE
IRLPLHQENVSLMLGDPTPGDNNSDDLGSDPYQPLDNTP
EEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNHGPGLTFRFLTAQVLVVVISLLVAAAVATMVGPTLFHDHMLMTGREDPSLELFHAEQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCEEEEEHHHH
YRDANLITLAVALPTALISALLASLWLSRRLRTPLQDLTRAATSLTAGNYRIRVPAGEAG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCC
PEVTTLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLSVLTVYFDGLQDGVVDWNNAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
HTIMADQLTRLTRLMEDIDDVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
QVETITDTVRVLVDRQRFGQVMSNLLSNALRHTPAGGQVRISVRRQGASTALIHVADDGE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCC
GIPPGQLGHIFERFYRGDAARSRDNGGAGIGLTISKALIEAHGGTLTATSPGPGAGSVFT
CCCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCCEEE
IRLPLHQENVSLMLGDPTPGDNNSDDLGSDPYQPLDNTP
EEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]