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The map label for this gene is ureG

Identifier: 145294150

GI number: 145294150

Start: 123062

End: 123679

Strand: Direct

Name: ureG

Synonym: cgR_0108

Alternate gene names: 145294150

Gene position: 123062-123679 (Clockwise)

Preceding gene: 145294149

Following gene: 145294151

Centisome position: 3.71

GC content: 51.13

Gene sequence:

>618_bases
ATGGGTCCAATCAGAATCGGCGTAGGCGGACCGGTCGGCGCCGGCAAAACGCAGCTGGTAGAGCGGATTACGCGAGCGCT
TATCGACGAAGTCAGCATGGCTGCAATCACTAACGATATCTATACCATTGAAGACGCCAAGATTCTTGCCGCTAATGGTG
TGCTGCCAGAGGAACGCATTGTTGGCATTGAAACTGGTGGATGCCCACACACTGCGATTCGTGAAGACACCTCCATGAAT
GATGCCGCGATCAAAGACCTCGTGGAGCGCTTCCCAGACTTGGAGCTCATCTTCGTGGAATCCGGCGGAGATAACCTTTC
TGCGACTTTCTCCCCAGAGTTAGTGGATTTCTCCATCTACATCATTGATGTTGCCCAAGGCGAGAAGATCCCGAGGAAAG
CTGGCCAAGGCATGATTAAGTCGGATTTGTTCATCATCAACAAGACAGATCTTGCTCCATACGTTGGTGCCAACCTTGAT
GTCATGGTGGAAGATGCCAAGACATTCCGTAAAAACAAACCATTCTGCCTGACCAATCTGCGTACCGATGACGGTTTGGA
CAAGGTCTTGGAATGGATCCGCCATGAGGTGATGATGCAGGACTTGCAGGAAGCCTAA

Upstream 100 bases:

>100_bases
ATTGATTTCTGTTCTGGCGATCCAGGCTTGGATATTTCACAAATGGTTCATGAAACCCAACGTGCACGACTATTTATGAG
TTAAGAAGGAGAAAAGAAAA

Downstream 100 bases:

>100_bases
ATGACACAAACCCAACCAGTGGGAACCCTGCGACTCACCATTGATGATCAAGGACCCCAAGGTCAAAGCCGTGCGGTGGA
ACAATTCCACCAGGGTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MGPIRIGVGGPVGAGKTQLVERITRALIDEVSMAAITNDIYTIEDAKILAANGVLPEERIVGIETGGCPHTAIREDTSMN
DAAIKDLVERFPDLELIFVESGGDNLSATFSPELVDFSIYIIDVAQGEKIPRKAGQGMIKSDLFIINKTDLAPYVGANLD
VMVEDAKTFRKNKPFCLTNLRTDDGLDKVLEWIRHEVMMQDLQEA

Sequences:

>Translated_205_residues
MGPIRIGVGGPVGAGKTQLVERITRALIDEVSMAAITNDIYTIEDAKILAANGVLPEERIVGIETGGCPHTAIREDTSMN
DAAIKDLVERFPDLELIFVESGGDNLSATFSPELVDFSIYIIDVAQGEKIPRKAGQGMIKSDLFIINKTDLAPYVGANLD
VMVEDAKTFRKNKPFCLTNLRTDDGLDKVLEWIRHEVMMQDLQEA
>Mature_204_residues
GPIRIGVGGPVGAGKTQLVERITRALIDEVSMAAITNDIYTIEDAKILAANGVLPEERIVGIETGGCPHTAIREDTSMND
AAIKDLVERFPDLELIFVESGGDNLSATFSPELVDFSIYIIDVAQGEKIPRKAGQGMIKSDLFIINKTDLAPYVGANLDV
MVEDAKTFRKNKPFCLTNLRTDDGLDKVLEWIRHEVMMQDLQEA

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

Organism=Escherichia coli, GI1789082, Length=185, Percent_Identity=27.027027027027, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_CORGB (A4QA26)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001136971.1
- ProteinModelPortal:   A4QA26
- SMR:   A4QA26
- STRING:   A4QA26
- GeneID:   4992462
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0108
- eggNOG:   COG0378
- HOGENOM:   HBG364734
- OMA:   LCKAMRE
- ProtClustDB:   CLSK899973
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 22448; Mature: 22317

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPIRIGVGGPVGAGKTQLVERITRALIDEVSMAAITNDIYTIEDAKILAANGVLPEERI
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCHHHE
VGIETGGCPHTAIREDTSMNDAAIKDLVERFPDLELIFVESGGDNLSATFSPELVDFSIY
EEEECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCEEEEEEE
IIDVAQGEKIPRKAGQGMIKSDLFIINKTDLAPYVGANLDVMVEDAKTFRKNKPFCLTNL
EEEECCCCCCCHHHCCCCCCCCEEEEECCCCCHHCCCCEEEEEECHHHHHCCCCEEEEEC
RTDDGLDKVLEWIRHEVMMQDLQEA
CCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GPIRIGVGGPVGAGKTQLVERITRALIDEVSMAAITNDIYTIEDAKILAANGVLPEERI
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCHHHE
VGIETGGCPHTAIREDTSMNDAAIKDLVERFPDLELIFVESGGDNLSATFSPELVDFSIY
EEEECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCEEEEEEE
IIDVAQGEKIPRKAGQGMIKSDLFIINKTDLAPYVGANLDVMVEDAKTFRKNKPFCLTNL
EEEECCCCCCCHHHCCCCCCCCEEEEECCCCCHHCCCCEEEEEECHHHHHCCCCEEEEEC
RTDDGLDKVLEWIRHEVMMQDLQEA
CCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA